The Volume Of The Heart PDF Download
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Author | : R. John Solaro |
Publisher | : Biota Publishing |
Total Pages | : 46 |
Release | : 2011-04-01 |
Genre | : Medical |
ISBN | : 1615041753 |
Download Regulation of Cardiac Contractility Book in PDF, ePub and Kindle
Contractility describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload (arterial pressure) and preload (end-diastolic volume; EDV). Various measures of contractility are related to the fraction as the SV/EDV or the ejection fraction, and the dynamics of ejection as determined from maximum pressure rise in the ventricles or arteries or from aortic flow velocities determined by echocardiography. At the cellular level, the ultimate determinant of contractility is the relative tension generation and shortening capability of the molecular motors (myosin cross-bridges) of the sarcomeres as determined by the rates and extent of Ca activation, the turnover kinetics of the cross-bridges, and the relative Ca responsiveness of the sarcomeres. Engagement of the regulatory signaling cascades controlling contractility occurs with occupancy and signal transduction by receptors for neurohumors of the autonomic nervous system as well as growth and stress signaling pathways. Contractility is also determined by the prevailing conditions of pH, temperature, and redox state. Short-term control of contractility is fully expressed during exercise. In long-term responses to stresses on the heart, contractility is modified by cellular remodeling and altered signaling that may compensate for a time but which ultimately may fail, leading to disorders.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 208 |
Release | : 1999-11-05 |
Genre | : Medical |
ISBN | : 0309064813 |
Download Fluid Resuscitation Book in PDF, ePub and Kindle
Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood lossâ€"hemorrhageâ€"is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties. In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research. The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.
Author | : Michitoshi Inoue |
Publisher | : Springer Science & Business Media |
Total Pages | : 330 |
Release | : 2013-11-09 |
Genre | : Medical |
ISBN | : 4431683674 |
Download Regulation of Coronary Blood Flow Book in PDF, ePub and Kindle
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Author | : J. Gordon Betts |
Publisher | : |
Total Pages | : 0 |
Release | : 2013-04-25 |
Genre | : |
ISBN | : 9781947172807 |
Download Anatomy and Physiology Book in PDF, ePub and Kindle
Author | : Richard E. Klabunde |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 689 |
Release | : 2020-12-01 |
Genre | : Medical |
ISBN | : 1975150090 |
Download Cardiovascular Physiology Concepts Book in PDF, ePub and Kindle
Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice.
Author | : David C. Warltier |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 404 |
Release | : 1995 |
Genre | : Medical |
ISBN | : |
Download Ventricular Function Book in PDF, ePub and Kindle
Author | : Rollin McCraty |
Publisher | : |
Total Pages | : 114 |
Release | : 2015 |
Genre | : |
ISBN | : 9781513606361 |
Download Science of the Heart - Exploring the Role of the Heart in Human Performance Book in PDF, ePub and Kindle
Author | : David Young |
Publisher | : Biota Publishing |
Total Pages | : 110 |
Release | : 2010-01-01 |
Genre | : Medical |
ISBN | : 1615040226 |
Download Control of Cardiac Output Book in PDF, ePub and Kindle
Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography
Author | : Peter Libby |
Publisher | : Elsevier Health Sciences |
Total Pages | : 8184 |
Release | : 2007-11-21 |
Genre | : Medical |
ISBN | : 1437721834 |
Download Braunwald's Heart Disease Book in PDF, ePub and Kindle
Dr. Braunwald's masterwork returns ... bringing you the definitive guidance you need to overcome any challenge in clinical cardiology today, using the best approaches available! Hundreds of world authorities, many of them new to this edition, synthesize all of the recent developments that are revolutionizing practice - from the newest findings in molecular biology and genetics to the latest imaging modalities, interventional procedures, and medications. This multimedia e-dition includes not only the printed reference, but also access to the complete contents online, fully searchable, with regular updates and much more. The expertise of the contributors, the scope of the coverage, and the versatile, multimedia format all make this the ultimate reference for the practicing cardiologist. Locate the answers you need fast, thanks to a user-friendly, full-color design, complete with more than 1,500 color illustrations. Glean clinically actionable information quickly with Clinical Practice Points in every chapter. Access the complete contents of the 2-volume set online, fully searchable, plus regular updates to reflect the latest clinical developments · Focused Reviews · Commentaries · Late-Breaking Trials · and more. Apply the latest knowledge in your field with 7 new chapters on Acute Heart Failure · Device Therapy of Heart Failure · Emerging Therapies for Heart Failure · Complementary and Alternative Approaches to Management · Prevention and Management of Stroke · Hypertrophic Cardiomyopathy · and Coronary Arteriography Guidelines. Get fresh perspectives on your practice with contributions from more than 20 brand-new authors.
Author | : Alexis Salerno |
Publisher | : Springer Nature |
Total Pages | : 192 |
Release | : 2022-01-28 |
Genre | : Medical |
ISBN | : 3030746879 |
Download Atlas of Critical Care Echocardiography Book in PDF, ePub and Kindle
This atlas covers the basics of ultrasound physics, provides the necessary background to successfully perform TEE and TTE procedures, and provides tips and tricks that will prove invaluable in the critical care environment. It also features an abundance of high quality photographs, illustrations and videos as well as numerous case studies to test the reader's ability to apply knowledge to real-life clinical situations. Written by experts in the field, The Atlas of Critical Care Echocardiography is a concise, visual guide designed for use by all physicians who see cardiac patients in the ICU.