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Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in Central Nervous System Regenerative Medicine
Author: António Salgado
Publisher: Elsevier
Total Pages: 712
Release: 2020-06-10
Genre: Medical
ISBN: 0128180854

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Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path


The Biology of Oligodendrocytes

The Biology of Oligodendrocytes
Author: Patricia Armati
Publisher: Cambridge University Press
Total Pages:
Release: 2010-10-21
Genre: Medical
ISBN: 1139491717

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Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.


Membrane Biogenesis

Membrane Biogenesis
Author: Jos A.F. Op den Kamp
Publisher: Springer Science & Business Media
Total Pages: 474
Release: 2013-06-29
Genre: Science
ISBN: 3642731848

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Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.


Glycobiology of the Nervous System

Glycobiology of the Nervous System
Author: Robert K. Yu
Publisher: Springer
Total Pages: 590
Release: 2014-08-23
Genre: Medical
ISBN: 1493911546

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A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.


Veterinary Neuroanatomy and Clinical Neurology

Veterinary Neuroanatomy and Clinical Neurology
Author: Alexander DeLahunta
Publisher: Elsevier Health Sciences
Total Pages: 551
Release: 2009
Genre: Neuroanatomy
ISBN: 0721667066

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Organized by functional neurologic system, the 3rd edition of this authoritative reference provides the most up-to-date information on neuroanatomy, neurophysiology, neuropathology, and clinical neurology as it applies to small animals, horses, and food animals. Accurate diagnosis is emphasized throughout with practical guidelines for performing neurologic examinations, interpreting examination results, and formulating effective treatment plans. In-depth disease descriptions, color images, and video clips reinforce important concepts and assist with diagnosis and treatment. Expert authors bring more than 50 years of experience in veterinary neuroanatomy and clinical neurology to this book - Dr. Alexander DeLahunta and Dr. Eric Glass offer their unique insights from both academic and practitioner perspectives. Disease content is presented in a logical case study format with three distinct parts: Description of the disorder Neuroanatomic diagnosis (including how it was determined, the differential diagnosis, and any available ancillary data) Course of the disease (providing final clinical or necropsy diagnosis and a brief discussion of the syndrome) More than 600 full-color photographs and line drawings, plus approximately 150 high-quality radiographs, visually reinforce key concepts and assist in reaching accurate diagnoses. The book comes with free access to 370 video clips on Cornell University's website that directly correlate to the case studies throughout the book and clearly demonstrate nearly every recognized neurologic disorder. High-quality MR images of the brain are presented alongside correlating stained transverse sections for in-depth study and comparison. Vivid photos of gross and microscopic lesions clearly illustrate the pathology of many of the disorders presented in the book.


Development of the Nervous System

Development of the Nervous System
Author: Dan H. Sanes
Publisher: Elsevier
Total Pages: 388
Release: 2005-11-02
Genre: Science
ISBN: 0080472494

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Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. Updates information including all the new developments made in the field since the first edition Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated


Basic Neurochemistry

Basic Neurochemistry
Author: R. Wayne Albers
Publisher: Academic Press
Total Pages: 1121
Release: 2011-11-02
Genre: Science
ISBN: 0080959016

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Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475


Anatomy & Physiology

Anatomy & Physiology
Author: Lindsay Biga
Publisher:
Total Pages:
Release: 2019-09-26
Genre:
ISBN: 9781955101158

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