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Behavioral Neurobiology of Psychedelic Drugs

Behavioral Neurobiology of Psychedelic Drugs
Author: Adam L. Halberstadt
Publisher: Springer
Total Pages: 434
Release: 2018-03-27
Genre: Medical
ISBN: 3662558807

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This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs. Examples of drugs within this group include LSD, psilocybin, and mescaline. Despite their structural differences, these compounds produce remarkably similar experiences in humans and share a common mechanism of action. Commonalities among the substances in this family are addressed both at the clinical and phenomenological level and at the basic neurobiological mechanism level. To the extent possible, contributions relate the clinical and preclinical findings to one another across species. The volume addresses both the risks associated with the use of these drugs and the potential medical benefits that might be associated with these and related compounds.


Psychedelic Neuroscience

Psychedelic Neuroscience
Author: Tanya Calvey
Publisher: Academic Press
Total Pages: 261
Release: 2018-11-21
Genre: Medical
ISBN: 0128142561

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We are in the midst of what is being called the ‘psychedelic renaissance’ with growing interest into how psychedelics alter consciousness, brain function and brain connectivity. The acute, often profound, effects of the psychedelic experience can induce lasting improvements in mental health demonstrating that chemistry forms the basis of mystical experience, consciousness and mental wellbeing. This volume is a collection of chapters by world leaders in fields of neurobiology, neuropsychiatry, psychology, ethnography and pharmacology, addressing the neurobiological mechanisms of action of various classic and atypical psychedelics, their therapeutic potential as well as the possible risks associated with their use


Neuropsychedelia

Neuropsychedelia
Author: Nicolas Langlitz
Publisher: Univ of California Press
Total Pages: 334
Release: 2013
Genre: Medical
ISBN: 0520274822

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Neuropsychedelia examines the revival of psychedelic science since the "Decade of the Brain." After the breakdown of this previously prospering area of psychopharmacology, and in the wake of clashes between counterculture and establishment in the late 1960s, a new generation of hallucinogen researchers used the hype around the neurosciences in the 1990s to bring psychedelics back into the mainstream of science and society. This book is based on anthropological fieldwork and philosophical reflections on life and work in two laboratories that have played key roles in this development: a human lab in Switzerland and an animal lab in California. It sheds light on the central transnational axis of the resurgence connecting American psychedelic culture with the home country of LSD. In the borderland of science and religion, Neuropsychedelia explores the tensions between the use of hallucinogens to model psychoses and to evoke spiritual experiences in laboratory settings. Its protagonists, including the anthropologist himself, struggle to find a place for the mystical under conditions of late-modern materialism.


How to Change Your Mind

How to Change Your Mind
Author: Michael Pollan
Publisher: Penguin
Total Pages: 481
Release: 2018-05-15
Genre: Body, Mind & Spirit
ISBN: 0525558942

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“Pollan keeps you turning the pages . . . cleareyed and assured.” —New York Times A #1 New York Times Bestseller, New York Times Book Review 10 Best Books of 2018, and New York Times Notable Book A brilliant and brave investigation into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists inadvertently catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both suffering and joy, we can do our best to be fully present and find meaning in our lives.


The Neuroscience of Psychedelics

The Neuroscience of Psychedelics
Author: Genís Ona
Publisher: Simon and Schuster
Total Pages: 340
Release: 2024-10-08
Genre: Medical
ISBN:

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• Examines the main pharmacological properties of psychedelic substances, including LSD, DMT, psilocybin, ayahuasca, mescaline, ketamine, ibogaine, salvia, and MDMA • Explains the physiological mechanisms behind visionary effects, including what is happening in the brain and how each psychedelic is processed by the body • Shares safe strategies for using psychedelics, including harm-reduction techniques, and looks at where the future of psychedelic therapies is likely to go With the widespread legalization of marijuana and the increasing use of psychoactives in controlled therapy settings, further research and understanding of psychedelics is now possible. Yet while individual accounts of their use abound, exactly what’s happening to the brain and body when using these substances is still not widely understood. Longtime pharmacological researcher Genís Ona presents a comprehensive look at the main pharmacological properties of psychedelic substances, including LSD, DMT, psilocybin, ayahuasca, mescaline, ketamine, ibogaine, salvia, tropane alkaloids, and MDMA. Exploring how psychedelics work within the brain, Ona shares results from his extensive research to reveal the physiological mechanisms that allow these molecules to have their visionary effects, explaining what is happening at the receptor level as well as the “cascade” effects that differ from substance to substance. He examines how the body processes each substance, describing how each psychedelic is released, absorbed, distributed, metabolized, and eliminated. He also details possible dangerous interactions between these substances and other drugs as well as their potential toxicity. Although his main focus is the biological and neurological effects of psychedelics, Ona also explores the mystical and spiritual dimension of psychedelic use, particularly as practiced in Indigenous traditions, showing how they enable access to a profound spiritual territory. He shares safe strategies for using psychedelics and looks at where the future of psychedelic therapies is likely to go, with an emphasis on ensuring that traditional knowledge is respected, honored, and protected.


Philosophy of Psychedelics

Philosophy of Psychedelics
Author: Chris Letheby
Publisher: Oxford University Press
Total Pages: 175
Release: 2021-08-05
Genre: Medical
ISBN: 0192581090

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Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely in controlled conditions, and can cause lasting psychological benefits with one or two administrations. Supervised psychedelic sessions can reduce symptoms of anxiety, depression, and addiction, and improve well-being in healthy volunteers, for months or even years. But these benefits seem to be mediated by "mystical" experiences of cosmic consciousness, which prompts a philosophical concern: do psychedelics cause psychological benefits by inducing false or implausible beliefs about the metaphysical nature of reality? This book is the first scholarly monograph in English devoted to the philosophical analysis of psychedelic drugs. Its central focus is the apparent conflict between the growing use of psychedelics in psychiatry and the philosophical worldview of naturalism. Within the book, Letheby integrates empirical evidence and philosophical considerations in the service of a simple conclusion: this "Comforting Delusion Objection" to psychedelic therapy fails. While exotic metaphysical ideas do sometimes come up, they are not, on closer inspection, the central driver of change in psychedelic therapy. Psychedelics lead to lasting benefits by altering the sense of self, and changing how people relate to their own minds and lives-not by changing their beliefs about the ultimate nature of reality. The upshot is that a traditional conception of psychedelics as agents of insight and spirituality can be reconciled with naturalism (the philosophical position that the natural world is all there is). Controlled psychedelic use can lead to genuine forms of knowledge gain and spiritual growth-even if no Cosmic Consciousness or transcendent divine Reality exists. Philosophy of Psychedelics is an indispensable guide to the literature for researchers already engaged in the field of psychedelic psychiatry, and for researchers-especially philosophers-who want to become acquainted with this increasingly topical field.


The Psychedelic Handbook

The Psychedelic Handbook
Author: Rick Strassman
Publisher: Simon and Schuster
Total Pages: 216
Release: 2022-08-09
Genre: Health & Fitness
ISBN: 1646043812

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Learn everything you need to know about psychedelics with this ultimate guide packed with information on popular psychoactive drugs like psilocybin, ketamine, MDMA, DMT and LSD--plus practical tips for microdosing and how to safely "trip"--from bestselling author Dr. Rick Strassman. Entering the world of psychedelics can be daunting, and many aren't sure where to start. Research continues to expand and legalization looms on the horizon for psychedelics like psilocybin. The Psychedelic Handbook is a complete manual that explains the basics of psychedelics in a way that is accessible for the novice user--or even just the psychedelic-curious. Inside you'll find: Information on the science and history of psychedelics Basic information on popular psychedelics like psilocybin, LSD, and peyote The difference between psychedelics and other "psychedelic-like" such as MDMA and ketamine The healing potential of psychedelic medicine for depression, PTSD, and anxiety And much more! Clinical research psychiatrist and bestselling author of DMT: The Spirit Molecule, Dr. Rick Strassman offers his expert advice for safely and effectively reaping the benefits of psychedelic medicine.


Psychedelic Drugs Reconsidered

Psychedelic Drugs Reconsidered
Author: Lester Grinspoon
Publisher: Bookworld Services
Total Pages: 385
Release: 1997
Genre: Hallucinogenic drugs
ISBN: 9780964156852

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First published in 1979, Psychedelic Drugs Reconsidered is regarded by many as the most comprehensive, accurate, and accessible analysis of psychedelic drugs for the general reader. It records the extensive history of scientific research on, and societal experience with, psychedelic drugs. The Lindesmith Center reprint edition features a new introduction by the authors on recent developments in psychedelic research, as well as a preface by Dr. Ethan Nadelmann, director of the Lindesmith center.


Psychedelics and mental health

Psychedelics and mental health
Author: Irene de Caso
Publisher: ArgoNowta
Total Pages: 317
Release: 2022-05-01
Genre: Medical
ISBN: 8418943327

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Irene de Caso explains in an understandable and entertaining way the current neuroscientific advances related to psychedelic drugs, as well as their clinical and experiential applications. José Carlos Bouso, PhD, Scientific Director, ICEERS. Learn about the therapeutic uses of classical psychedelics and empathogens as revolutionary tools for neuroplasticity and mental health. Discover how they promote profoundly revealing mental states capable of restructuring our internal models of the world, reconsolidate traumatic memories and improve our social relationships. How do they affect the brain? What characteristics make these substances powerful catalysts for the psychotherapeutic process? Learn how they can help to improve severe symptoms: addictions, treatment-resistant depression, anxiety or post-traumatic stress. This illustrated guide describes the most important clinical studies and will be of great interest to all medical and mental health professionals seeking to understand the cutting edge clinical applications of these molecules, as well as to individuals interested in learning about the potential of psychedelic-assisted therapies.


Your brain on psychedelics

Your brain on psychedelics
Author: Genis Ona
Publisher: ArgoNowta
Total Pages: 255
Release: 2022-05-01
Genre: Medical
ISBN: 8418943351

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To understand the pharmacology of psychedelics is to understand the essence of what makes us human. Genís Oña makes an informative, entertaining and understandable approach to the science of psychedelics. José Carlos Bouso, PhD, Scientific Director, ICEERS. Discover the pharmacology of psychedelics. Delve into the cutting edge of scientific research on the impact of psilocybin, MDMA, DMT, mescaline and LSD on the brain. With this guide you will learn the keys to the effects of psychedelics, capable of producing significant changes in the processes of perception, thought and consciousness. An illustrated guide to understanding the science behind new psychedelic-assisted therapies for treating mental health issues. This essential guide will be of interest to all psychonauts eager to immerse themselves in the pharmacology of the most popular psychedelic molecules, to all medical and mental health professionals, and to all people interested in learning the essentials of the neuroscience of psychedelic molecules and how they affect our brains.