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Sequence — Evolution — Function

Sequence — Evolution — Function
Author: Eugene V. Koonin
Publisher: Springer Science & Business Media
Total Pages: 482
Release: 2013-06-29
Genre: Science
ISBN: 1475737831

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Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.


Evolution of Metabolic Pathways

Evolution of Metabolic Pathways
Author: R. Ibrahim
Publisher: Elsevier
Total Pages: 481
Release: 2000-09-15
Genre: Science
ISBN: 0080531326

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The past decade has seen major advances in the cloning of genes encoding enzymes of plant secondary metabolism. This has been further enhanced by the recent project on the sequencing of the Arabidopsis genome. These developments provide the molecular genetic basis to address the question of the Evolution of Metabolic Pathways. This volume provides in-depth reviews of our current knowledge on the evolutionary origin of plant secondary metabolites and the enzymes involved in their biosynthesis. The chapters cover five major topics: 1. Role of secondary metabolites in evolution; 2. Evolutionary origins of polyketides and terpenes; 3. Roles of oxidative reactions in the evolution of secondary metabolism; 4. Evolutionary origin of substitution reactions: acylation, glycosylation and methylation; and 5. Biochemistry and molecular biology of brassinosteroids.


Evolution of Metabolic Pathways

Evolution of Metabolic Pathways
Author: John T. Romeo
Publisher: Pergamon Press
Total Pages: 467
Release: 2000
Genre: Science
ISBN: 9780080438603

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The past decade has seen major advances in the cloning of genes encoding enzymes of plant secondary metabolism. This has been further enhanced by the recent project on the sequencing of the Arabidopsis genome. These developments provide the molecular genetic basis to address the question of the Evolution of Metabolic Pathways. This volume provides in-depth reviews of our current knowledge on the evolutionary origin of plant secondary metabolites and the enzymes involved in their biosynthesis. The chapters cover five major topics: 1. Role of secondary metabolites in evolution; 2. Evolutionary origins of polyketides and terpenes; 3. Roles of oxidative reactions in the evolution of secondary metabolism; 4. Evolutionary origin of substitution reactions: acylation, glycosylation and methylation; and 5. Biochemistry and molecular biology of brassinosteroids.


The Evolution of the Transcriptional Regulation of Amino Acid Biosynthetic Pathways in Yeasts

The Evolution of the Transcriptional Regulation of Amino Acid Biosynthetic Pathways in Yeasts
Author: Liron Noiman
Publisher:
Total Pages:
Release: 2021
Genre:
ISBN:

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When evolutionary biology comes to mind, it is often accompanied by contemplating the vast amount of morphological or behavioral differences that exist between species. Whether Darwin's finches or the pattern on an insect wing, we often reference these types of striking apparent visual differences in discussing the power of evolution. However, there are a growing number of examples that suggest that even core, fundamental processes like metabolism and mating are subject to evolutionary changes. In the face of these underlying evolutionary changes, the fundamental logic of these core processes must be conserved. A biosynthetic pathway must be upregulated in the face of nutrient starvation (Ch. 1), and a cellular identity must be conserved in order for mating to occur in yeast (Ch. 2), but how these logical outputs are maintained in spite of evolution acting on the molecules involved in these processes is the outstanding question explored in this work.


Photosynthesis

Photosynthesis
Author: Julian J. Eaton-Rye
Publisher: Springer Science & Business Media
Total Pages: 874
Release: 2011-11-04
Genre: Science
ISBN: 940071579X

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“Photosynthesis: Plastid Biology, Energy Conversion and Carbon Assimilation” was conceived as a comprehensive treatment touching on most of the processes important for photosynthesis. Most of the chapters provide a broad coverage that, it is hoped, will be accessible to advanced undergraduates, graduate students, and researchers looking to broaden their knowledge of photosynthesis. For biologists, biochemists, and biophysicists, this volume will provide quick background understanding for the breadth of issues in photosynthesis that are important in research and instructional settings. This volume will be of interest to advanced undergraduates in plant biology, and plant biochemistry and to graduate students and instructors wanting a single reference volume on the latest understanding of the critical components of photosynthesis.


The Evolution of Metabolic Function

The Evolution of Metabolic Function
Author: Robert P. Mortlock
Publisher: CRC Press
Total Pages: 354
Release: 1992-05-20
Genre: Medical
ISBN: 9780849388637

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The Evolution of Metabolic Function presents comprehensive discussions on a variety of topics that will interest scientists and students studying the evolution of enzyme activities, the evolution of enzymatic pathways, and the evolution and development of metabolic functions. Laboratory experiments designed to develop new enzyme activities and new metabolic pathways are discussed. The most recent techniques comparing protein and gene structures are used to analyze and discuss the evolution and development of such metabolic functions as the bacterial phosphoenolpyruvate:sugar phosphotransferase system, the mandelate pathway of microorganisms, bacterial alcohol metabolism, and certain microbial amino acid biosynthetic pathways. The book also includes some unique speculations regarding the origin of early Archaean cells and the prebiotic evolution of complex molecules.


Chemical and Biological Synthesis

Chemical and Biological Synthesis
Author: Nick J Westwood
Publisher: Royal Society of Chemistry
Total Pages: 317
Release: 2018-08-16
Genre: Science
ISBN: 178801507X

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Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.