The Development of the Vascular System
Author | : Richard N. Feinberg |
Publisher | : S. Karger AG (Switzerland) |
Total Pages | : 208 |
Release | : 1991 |
Genre | : Medical |
ISBN | : |
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Author | : Richard N. Feinberg |
Publisher | : S. Karger AG (Switzerland) |
Total Pages | : 208 |
Release | : 1991 |
Genre | : Medical |
ISBN | : |
Author | : Roland N. Pittman |
Publisher | : Biota Publishing |
Total Pages | : 117 |
Release | : 2016-08-18 |
Genre | : Medical |
ISBN | : 1615047212 |
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author | : Derek J. Chadwick |
Publisher | : John Wiley & Sons |
Total Pages | : 260 |
Release | : 2007-08-20 |
Genre | : Science |
ISBN | : 0470319429 |
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.
Author | : Domenico Ribatti |
Publisher | : Academic Press |
Total Pages | : 126 |
Release | : 2022-06-02 |
Genre | : Science |
ISBN | : 0323915795 |
New Insights on the Development of the Vascular System examines the most recent literature and data on the development of the vascular system, along with advice on new laboratory techniques and approaches to data analysis. This volume is a comprehensive handbook to the state-of-the-art in vascular system development. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system, and there is extensive literature on the genetic background and molecular mechanisms responsible for blood vessel formation. Yet new data and techniques have been developed in recent years. Although scientific literature covers the descriptive aspects of embryonic vascular system development, modern techniques such as the technology of cell fusion, cell sorting and image analysis give new insight into the mechanisms by which vessels form and regress and how blood flow changes directions in the same vessels. Gives a comprehensive overview of the most recent literature in the field of vascular system development Presents new data, including sections on endothelial cell signaling and technologies of cell fusion, cell sorting and image analysis Provides useful insights on the analysis of new experimental work Suggests modern techniques for scientists to use in the lab Gives an overview of vascular biology that will be useful for those needing rapid familiarity Provides an expert guide to the state-of-the-art in vascular system development as written by a leader in the field
Author | : Friedemann Kiefer |
Publisher | : Springer Science & Business Media |
Total Pages | : 212 |
Release | : 2013-11-26 |
Genre | : Medical |
ISBN | : 3709116465 |
The book focuses on the lymphatic vascular system from a developmental biologist’s point of view. It provides an overview on the many recent advances in understanding the development of lymphatic vessels, using advanced genetic models in conjunction with state of the art imaging. For each chapter a synopsis is provided, highlighting the main points in a concise manner. The book is intended for professors and researchers in vascular biology, angiogenesis research and developmental biology. It furthermore offers an excellent basis for entry level researchers and newcomers to this field, as well as for teachers, graduate students, advanced science and medical students.
Author | : Michitoshi Inoue |
Publisher | : Springer Science & Business Media |
Total Pages | : 330 |
Release | : 2013-11-09 |
Genre | : Medical |
ISBN | : 4431683674 |
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Author | : B. H.. Jägerross |
Publisher | : |
Total Pages | : 86 |
Release | : 1934 |
Genre | : |
ISBN | : |
Author | : Jonathan Nugent |
Publisher | : John Wiley & Sons |
Total Pages | : 192 |
Release | : 2009-09-14 |
Genre | : Science |
ISBN | : 047071851X |
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Author | : Andreas Bikfalvi |
Publisher | : Springer |
Total Pages | : 188 |
Release | : 2018-04-13 |
Genre | : Medical |
ISBN | : 3319743767 |
This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it ́s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology.