The Causes Of Molecular Evolution PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The Causes Of Molecular Evolution PDF full book. Access full book title The Causes Of Molecular Evolution.
| Author | : John H. Gillespie |
| Publisher | : Oxford University Press |
| Total Pages | : 351 |
| Release | : 1994-05-26 |
| Genre | : Science |
| ISBN | : 0195357744 |
Download The Causes of Molecular Evolution Book in PDF, ePub and Kindle
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.
| Author | : John H. Gillespie |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 351 |
| Release | : 1991 |
| Genre | : DNA |
| ISBN | : 0195092716 |
Download The Causes of Molecular Evolution Book in PDF, ePub and Kindle
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book will be of interest to human geneticists, biologists, evolutionary theorists, and bio-mathematicians.
| Author | : John H. Gillespie |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2023 |
| Genre | : Population genetics |
| ISBN | : 9780197700501 |
Download The Causes of Molecular Evolution Book in PDF, ePub and Kindle
This work provides a unified theory that addresses the problem of the origin and maintenance of genetic variation in natural populations. It examines protein evolution, DNA evolution and molecular mechanisms, reviewing all experimental observations on genetic variation.
| Author | : Motoo Kimura |
| Publisher | : Cambridge University Press |
| Total Pages | : 388 |
| Release | : 1985-01-10 |
| Genre | : Science |
| ISBN | : 1139935674 |
Download The Neutral Theory of Molecular Evolution Book in PDF, ePub and Kindle
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
| Author | : |
| Publisher | : |
| Total Pages | : 336 |
| Release | : 1991 |
| Genre | : |
| ISBN | : |
Download The Causes of Molecular Evolution Book in PDF, ePub and Kindle
| Author | : Motoo Kimura |
| Publisher | : University of Chicago Press |
| Total Pages | : 736 |
| Release | : 1994 |
| Genre | : Science |
| ISBN | : 9780226435633 |
Download Population Genetics, Molecular Evolution, and the Neutral Theory Book in PDF, ePub and Kindle
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
| Author | : Roderick D.M. Page |
| Publisher | : John Wiley & Sons |
| Total Pages | : 352 |
| Release | : 2009-07-14 |
| Genre | : Science |
| ISBN | : 1444313363 |
Download Molecular Evolution Book in PDF, ePub and Kindle
The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.
| Author | : Simon Y. W. Ho |
| Publisher | : Springer Nature |
| Total Pages | : 245 |
| Release | : 2021-01-18 |
| Genre | : Science |
| ISBN | : 3030601811 |
Download The Molecular Evolutionary Clock Book in PDF, ePub and Kindle
This book presents coverage of the principles and practice of molecular clocks, which have provided fascinating and unprecedented insights into the evolutionary timescale of life on earth. It begins by following the early development of the molecular evolutionary clock in the 1960s, and leads to the complex statistical approaches that are now used to analyse genome sequences. The chapters of this book have been contributed by leading experts in the field and address the important issues of evolutionary rates, molecular dating, and phylogenomic analysis. This is the first time that these different aspects of the molecular clock have been brought together in a single, comprehensive volume. It is an invaluable reference for students and researchers interested in evolutionary biology, genetic analysis, and genomic evolution.
| Author | : Masatoshi Nei |
| Publisher | : Oxford University Press |
| Total Pages | : 444 |
| Release | : 2000-07-27 |
| Genre | : Science |
| ISBN | : 0199881227 |
Download Molecular Evolution and Phylogenetics Book in PDF, ePub and Kindle
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.
| Author | : Masatoshi Nei |
| Publisher | : OUP Oxford |
| Total Pages | : 261 |
| Release | : 2013-05-02 |
| Genre | : Science |
| ISBN | : 0199661731 |
Download Mutation-Driven Evolution Book in PDF, ePub and Kindle
The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.
