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Stem Cell Century

Stem Cell Century
Author: Russell Korobkin
Publisher: Yale University Press
Total Pages: 336
Release: 2007-01-01
Genre: Law
ISBN: 0300122926

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"Stem Cell Century provides a very clear analysis of the policy issues around cloning and stem cells in biomedicine, on the basis of a sound scientific understanding of the underlying biology." Ian Wilmut, director, Edinburgh University Centre for Regenerative Medicine, and creator of "Dolly" the lamb, the world's first cloned mammal. From the bookjacket.


Stem Cells and Public Policy

Stem Cells and Public Policy
Author: Richard Hayes
Publisher:
Total Pages: 0
Release: 2006
Genre: Biotechnology
ISBN: 9780870785030

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Stem Cells: Promise And Reality

Stem Cells: Promise And Reality
Author: Lygia V Pereira
Publisher: World Scientific
Total Pages: 106
Release: 2016-08-22
Genre: Science
ISBN: 9813100214

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Stem Cells: Promises and Reality will tell you everything you have always wanted to know about stem cells, but could not understand the field from elsewhere.Stem cells are the great therapeutic promise of the century, and this evolving field of research and medicine brings with it many legal, ethical and psychological issues that must be discussed by society as a whole.Written so as to be accessible to general readers as well as specialists, this book explains what stem cells are, and the different aspects of stem cell research and applications. The book will enable the reader to understand the field sufficiently to critically participate in the public debates regarding stem cell research and society and ethics. By the end of the book, the reader will also be able to judge news on the stem cells field, and to discern what are real advances and what are phony treatments.The main advantage of this book in comparison with other 'stem cells for the general public' books is that it assumes the reader knows NOTHING about biology, except what is already common knowledge (for example, that we are made of cells). The book constructs step by step the required basic biology knowledge in order for the reader to understand all the different aspects of stem cells. At the same time that it is thorough in its stem cells-based content, and will keep the reader engaged with its narrative.


Stem Cells - From Drug to Drug Discovery

Stem Cells - From Drug to Drug Discovery
Author: Khawaja Husnain Haider
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 269
Release: 2017-03-20
Genre: Science
ISBN: 3110493551

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Stem cell based therapy is a 21st century approach of therapeutic intervention which epitomizes a shift from conventional symptomatic treatment strategy to addressing the root cause of the disease process. This is especially a hope for the patients suffering from diseases such as Alzheimer, diabetes, myocardial infarction and other diseases which have always been considered as incurable. Moreover, stem cells provide excellent in vitro disease models for drug development. This book is a compilation of the bench experience of experts from various research labs involved in the cutting edge area of research, describing the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development.


Stem Cells

Stem Cells
Author: Christine L. Mummery
Publisher: Academic Press
Total Pages: 446
Release: 2014-05-23
Genre: Science
ISBN: 0124115675

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The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice


Stem Cells & Regenerative Medicine

Stem Cells & Regenerative Medicine
Author: Krishnarao Appasani
Publisher: Springer Science & Business Media
Total Pages: 632
Release: 2010-11-01
Genre: Science
ISBN: 1607618605

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Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.


Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 112
Release: 2002-01-25
Genre: Science
ISBN: 0309170427

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Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.


Stem Cells and Human Diseases

Stem Cells and Human Diseases
Author: Rakesh K. Srivastava
Publisher: Springer Science & Business Media
Total Pages: 633
Release: 2012-02-01
Genre: Medical
ISBN: 940072800X

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The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.


Stem Cell Transplantation

Stem Cell Transplantation
Author: Carlos López-Larrea
Publisher: Springer Science & Business Media
Total Pages: 365
Release: 2012-03-28
Genre: Science
ISBN: 1461420989

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Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.


Stem Cells and Aging

Stem Cells and Aging
Author: Surajit Pathak
Publisher: Academic Press
Total Pages: 322
Release: 2021-03-17
Genre: Science
ISBN: 0128204133

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Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population Addresses the effect of time and age on human stem cells Includes chapters from contributors exploring the biology of stem cell aging around the globe