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Statistics for Epidemiology

Statistics for Epidemiology
Author: Nicholas P. Jewell
Publisher: CRC Press
Total Pages: 376
Release: 2003-08-26
Genre: Medical
ISBN: 0203496868

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Statistical ideas have been integral to the development of epidemiology and continue to provide the tools needed to interpret epidemiological studies. Although epidemiologists do not need a highly mathematical background in statistical theory to conduct and interpret such studies, they do need more than an encyclopedia of "recipes." Statistics for Epidemiology achieves just the right balance between the two approaches, building an intuitive understanding of the methods most important to practitioners and the skills to use them effectively. It develops the techniques for analyzing simple risk factors and disease data, with step-by-step extensions that include the use of binary regression. It covers the logistic regression model in detail and contrasts it with the Cox model for time-to-incidence data. The author uses a few simple case studies to guide readers from elementary analyses to more complex regression modeling. Following these examples through several chapters makes it easy to compare the interpretations that emerge from varying approaches. Written by one of the top biostatisticians in the field, Statistics for Epidemiology stands apart in its focus on interpretation and in the depth of understanding it provides. It lays the groundwork that all public health professionals, epidemiologists, and biostatisticians need to successfully design, conduct, and analyze epidemiological studies.


Statistical Methods for Global Health and Epidemiology

Statistical Methods for Global Health and Epidemiology
Author: Xinguang Chen
Publisher: Springer Nature
Total Pages: 420
Release: 2020-04-13
Genre: Medical
ISBN: 3030352609

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This book examines statistical methods and models used in the fields of global health and epidemiology. It includes methods such as innovative probability sampling, data harmonization and encryption, and advanced descriptive, analytical and monitory methods. Program codes using R are included as well as real data examples. Contemporary global health and epidemiology involves a myriad of medical and health challenges, including inequality of treatment, the HIV/AIDS epidemic and its subsequent control, the flu, cancer, tobacco control, drug use, and environmental pollution. In addition to its vast scales and telescopic perspective; addressing global health concerns often involves examining resource-limited populations with large geographic, socioeconomic diversities. Therefore, advancing global health requires new epidemiological design, new data, and new methods for sampling, data processing, and statistical analysis. This book provides global health researchers with methods that will enable access to and utilization of existing data. Featuring contributions from both epidemiological and biostatistical scholars, this book is a practical resource for researchers, practitioners, and students in solving global health problems in research, education, training, and consultation.


Statistical Methods in Epidemiology

Statistical Methods in Epidemiology
Author: Harold A. Kahn
Publisher: Monographs in Epidemiology and
Total Pages: 310
Release: 1989
Genre: Medical
ISBN: 0195050495

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This book is an expanded version of the Kahn's widely used text, An Introduction to Epidemiologic Methods (Oxford, 1983). It provides clear insight into the basic statistical tools used in epidemiology and is written so that those without advanced statistical training can comprehend the ideas underlying the analytical techniques. The authors emphasize the extent to which similar results are obtained from different methods, both simple and complex. To this edition they have added a new chapter on "Comparison of Numerical Results for Various Methods of Adjustment" and also one on "The Primacy of Data Collection." New topics include the Kaplan-Meier product-limit method and the Cox proportional hazards model for analysis of time-related outcomes. An appendix of data from the Framingham Heart Study is used to illustrate the application of various analytical methods to an identical set of real data and provides source material for student exercises. The text has been updated throughout.


Statistical Methods for Environmental Epidemiology with R

Statistical Methods for Environmental Epidemiology with R
Author: Roger D. Peng
Publisher: Springer Science & Business Media
Total Pages: 151
Release: 2008-12-15
Genre: Medical
ISBN: 0387781676

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As an area of statistical application, environmental epidemiology and more speci cally, the estimation of health risk associated with the exposure to - vironmental agents, has led to the development of several statistical methods and software that can then be applied to other scienti c areas. The stat- tical analyses aimed at addressing questions in environmental epidemiology have the following characteristics. Often the signal-to-noise ratio in the data is low and the targets of inference are inherently small risks. These constraints typically lead to the development and use of more sophisticated (and pot- tially less transparent) statistical models and the integration of large hi- dimensional databases. New technologies and the widespread availability of powerful computing are also adding to the complexities of scienti c inves- gation by allowing researchers to t large numbers of models and search over many sets of variables. As the number of variables measured increases, so do the degrees of freedom for in uencing the association between a risk factor and an outcome of interest. We have written this book, in part, to describe our experiences developing and applying statistical methods for the estimation for air pollution health e ects. Our experience has convinced us that the application of modern s- tistical methodology in a reproducible manner can bring to bear subst- tial bene ts to policy-makers and scientists in this area. We believe that the methods described in this book are applicable to other areas of environmental epidemiology, particularly those areas involving spatial{temporal exposures.


Statistical Models in Epidemiology

Statistical Models in Epidemiology
Author: David Clayton
Publisher: Oxford University Press, USA
Total Pages: 376
Release: 2013-01-17
Genre: Mathematics
ISBN: 0199671184

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This self-contained account of the statistical basis of epidemiology has been written for those with a basic training in biology. It is specifically intended for students enrolled for a masters degree in epidemiology, clinical epidemiology, or biostatistics.


A Statistical Approach to Genetic Epidemiology

A Statistical Approach to Genetic Epidemiology
Author: Andreas Ziegler
Publisher: John Wiley & Sons
Total Pages: 522
Release: 2011-08-24
Genre: Science
ISBN: 3527633669

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A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on “Model Free Linkage Analysis of Quantitative Traits” in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery.


Mathematical and Statistical Estimation Approaches in Epidemiology

Mathematical and Statistical Estimation Approaches in Epidemiology
Author: Gerardo Chowell
Publisher: Springer Science & Business Media
Total Pages: 367
Release: 2009-06-06
Genre: Mathematics
ISBN: 9048123135

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Mathematical and Statistical Estimation Approaches in Epidemiology compiles t- oretical and practical contributions of experts in the analysis of infectious disease epidemics in a single volume. Recent collections have focused in the analyses and simulation of deterministic and stochastic models whose aim is to identify and rank epidemiological and social mechanisms responsible for disease transmission. The contributions in this volume focus on the connections between models and disease data with emphasis on the application of mathematical and statistical approaches that quantify model and data uncertainty. The book is aimed at public health experts, applied mathematicians and sci- tists in the life and social sciences, particularly graduate or advanced undergraduate students, who are interested not only in building and connecting models to data but also in applying and developing methods that quantify uncertainty in the context of infectious diseases. Chowell and Brauer open this volume with an overview of the classical disease transmission models of Kermack-McKendrick including extensions that account for increased levels of epidemiological heterogeneity. Their theoretical tour is followed by the introduction of a simple methodology for the estimation of, the basic reproduction number,R . The use of this methodology 0 is illustrated, using regional data for 1918–1919 and 1968 in uenza pandemics.


Statistical Methods in Genetic Epidemiology

Statistical Methods in Genetic Epidemiology
Author: Duncan C. Thomas
Publisher: Oxford University Press
Total Pages: 458
Release: 2004-01-29
Genre: Medical
ISBN: 0199748055

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This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.


Statistical Methods in Spatial Epidemiology

Statistical Methods in Spatial Epidemiology
Author: Andrew B. Lawson
Publisher: John Wiley & Sons
Total Pages: 302
Release: 2013-07-08
Genre: Medical
ISBN: 1118723171

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Spatial epidemiology is the description and analysis of the geographical distribution of disease. It is more important now than ever, with modern threats such as bio-terrorism making such analysis even more complex. This second edition of Statistical Methods in Spatial Epidemiology is updated and expanded to offer a complete coverage of the analysis and application of spatial statistical methods. The book is divided into two main sections: Part 1 introduces basic definitions and terminology, along with map construction and some basic models. This is expanded upon in Part II by applying this knowledge to the fundamental problems within spatial epidemiology, such as disease mapping, ecological analysis, disease clustering, bio-terrorism, space-time analysis, surveillance and infectious disease modelling. Provides a comprehensive overview of the main statistical methods used in spatial epidemiology. Updated to include a new emphasis on bio-terrorism and disease surveillance. Emphasizes the importance of space-time modelling and outlines the practical application of the method. Discusses the wide range of software available for analyzing spatial data, including WinBUGS, SaTScan and R, and features an accompanying website hosting related software. Contains numerous data sets, each representing a different approach to the analysis, and provides an insight into various modelling techniques. This text is primarily aimed at medical statisticians, researchers and practitioners from public health and epidemiology. It is also suitable for postgraduate students of statistics and epidemiology, as well professionals working in government agencies.


Epidemiology

Epidemiology
Author: Mark Woodward
Publisher: CRC Press
Total Pages: 844
Release: 2013-12-19
Genre: Mathematics
ISBN: 1482243202

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Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet