Role of Glia in Interleukin-1-induced Neurotoxicity
Author | : Peter Philip Thornton |
Publisher | : |
Total Pages | : 233 |
Release | : 2006 |
Genre | : |
ISBN | : |
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Author | : Peter Philip Thornton |
Publisher | : |
Total Pages | : 233 |
Release | : 2006 |
Genre | : |
ISBN | : |
Author | : Michael Aschner |
Publisher | : CRC Press |
Total Pages | : 477 |
Release | : 2004-12-28 |
Genre | : Medical |
ISBN | : 1420039741 |
Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.
Author | : Michael Aschner |
Publisher | : CRC Press |
Total Pages | : 480 |
Release | : 2004-12-28 |
Genre | : Medical |
ISBN | : 9780849317941 |
Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases. The book is structured to examine the interactions between glial cells and neurons during development, adulthood, and senescence, followed by specific examples of directly mediated glial neurotoxicity. The book also covers miscellaneous topics in glial physiology/biochemistry such as signaling and edema. The book includes coverage of advances in our knowledge and understanding of glial physiology and biochemistry. Discover what's new in the Second Edition: Neuronal-glia metabolic interactions Neuronal-glia interactions (glutamate homeostasis) Zinc transporters in glia Energy deprivation/mitochondrial dysfunction - unique astrocyte susceptibilities Astrocytes and MPTP neurotoxicity Astroglia and food toxins Current understanding of the importance of glia has caused a boom in published information. Yet while many of the published textbooks are multifaceted and multidisciplinary, none includes the role of glia in neurotoxicity. Written by leaders in the field of glial research, this text fills this missing gap in the literature. Broader in scope than the first edition, including contributions from internationally known researchers, this is still the only book dedicated to exploring the role of glial cells in mediating neurotoxicology. Features Summarizes the latest research in glial cell function gleaned from new techniques in imaging and molecular biology Contains tables and figures that give you quick and easy access to precise data Includes a contemporary summary of literature that puts information useful for grant submissions at your fingertips Features new chapters covering metabolic interactions, glutamate homeostasis, transporters, energy deprivation/mitochondrial dysfunction, astrocytes, and food toxins Explores the role of glial cells in mediating neurotoxicity and incorporates information on specific effects of many compounds
Author | : Abel Lajtha |
Publisher | : |
Total Pages | : |
Release | : 1982 |
Genre | : Neurochemistry |
ISBN | : |
Author | : Andrzej Mackiewicz |
Publisher | : |
Total Pages | : 554 |
Release | : 1995 |
Genre | : Medical |
ISBN | : |
This volume discusses the role of interleukin-6-type cytokines in haematopoietic cell proliferation, neuronal differentiation and acute phase response to inflammation. New data is presented concerning the structure and function of interleukin-6, the leukemia inhibitory factor, interleukin-11, oncostatin M and the ciliary neurotrophic factor. Also discussed is cytokine receptor function, common signal transduction mechanisms, the molecular basis of cytokine-mediated alterations in gene expression, and regulation of cell proliferation. Pre-clinical and clinical studies with these cytokines are evaluated.
Author | : Hardy J. Rideout |
Publisher | : Springer |
Total Pages | : 280 |
Release | : 2017-03-28 |
Genre | : Medical |
ISBN | : 3319499696 |
This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
Author | : Lawrence Kruger |
Publisher | : CRC Press |
Total Pages | : 458 |
Release | : 2009-11-24 |
Genre | : Health & Fitness |
ISBN | : 1439812101 |
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Author | : Joyce A. De Leo |
Publisher | : |
Total Pages | : 464 |
Release | : 2007 |
Genre | : Medical |
ISBN | : |
"Review of immune and glial factors within the peripheral and central nervous systems that relate to chronic pain states. Discussion of novel immune and glial targets for clinical pain control that may yield new analgesic drugs"--Provided by publisher.
Author | : Daniel Laskowitz |
Publisher | : CRC Press |
Total Pages | : 388 |
Release | : 2016-04-21 |
Genre | : Medical |
ISBN | : 1498766579 |
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author | : Jeffrey Noebels |
Publisher | : OUP USA |
Total Pages | : 1258 |
Release | : 2012-06-29 |
Genre | : Medical |
ISBN | : 0199746540 |
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.