Regeneration Stem Cells And Beyond PDF Download
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| Author | : Ellen Heber-Katz |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 202 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 364218846X |
Download Regeneration: Stem Cells and Beyond Book in PDF, ePub and Kindle
In this issue of Current Topics in Microbiology and Immunology the authors present a unique range of examples of the regenerative response and the role of stem cells from the amphibian to human. It seems that all roads lead to cells that have the plasticity to become something else, not only in the amphibian but also in the mammal.
| Author | : Felix B Engel |
| Publisher | : World Scientific |
| Total Pages | : 393 |
| Release | : 2012-03-22 |
| Genre | : Medical |
| ISBN | : 9814465259 |
Download Heart Regeneration: Stem Cells And Beyond Book in PDF, ePub and Kindle
Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury.This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials.
| Author | : Kristina Hug |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 463 |
| Release | : 2010-12-25 |
| Genre | : Science |
| ISBN | : 1607619598 |
Download Translational Stem Cell Research Book in PDF, ePub and Kindle
For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.
| Author | : D. O. N. C. REED |
| Publisher | : World Scientific |
| Total Pages | : 440 |
| Release | : 2015-10-06 |
| Genre | : Medical |
| ISBN | : 9814618284 |
Download Stem Cell Battles Book in PDF, ePub and Kindle
This is a one-of-a-kind book: combining easy-to-understand science, in-the-trenches political warfare, and inspirational stories. It aims to give hope to individuals and families who suffer from chronic disease or disability; to point out how ordinary people can make an extraordinary difference in the battle to ease suffering and save lives through supporting medical research; to share in "people talk" some of the amazing progress already achieved in the new field of stem cell research; to show how even such a magnificent success as the California stem cell program is under constant attack from ideological groups; to offer medical research as a force for international cooperation; to suggest how cure research lessens the need for the mountainous costs of endless care.Unparalleled background: the author has been involved in virtually every important stem cell battle (state, national, and international) since embryonic stem cell research began. The author works closely with Robert N. Klein, sponsor of the California stem cell program, the largest source of such stem cell research funding in the world. In addition, the author is an award-winning teacher as well as writer, and seeks to entertain as well as educate. His book is not only substantive, but also fun.The book would be a treasured gift: for anyone suffering an "incurable" illness or who is a caregiver for a loved one; for a college student considering a rewarding career in biomedicine; for scientists who want to protect and enhance their research funding; and for anyone who wants to see government respond to the needs of its citizenry. Chronic disease and disability are a prison: cure is the triumphant escape -- wheelchairs should be for temporary occupancy only.
| Author | : Peter Hollands |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 126 |
| Release | : 2020-12-03 |
| Genre | : Health & Fitness |
| ISBN | : 981148211X |
Download The Regeneration Promise: The Facts behind Stem Cell Therapies Book in PDF, ePub and Kindle
The Regeneration Promise is a reader-friendly guide to the world of regenerative medicine and stem cell technology. It covers the history of stem cell technology as a general introduction to the subject and then continues with a description of the many known types of stem cells and how these can potentially be used to treat disease. The author explains the pros and cons of using stem cell technology to treat patients in simple and factual terms throughout the book while clarifying many stem cell myths. There is valuable advice for people considering undergoing stem cell therapy and also for those who are considering stem cell storage such as umbilical cord blood storage at the birth of a baby. The book also covers information on current research in stem cell technology and how this may be useful in the clinic, as promising regenerative medicine treatments emerge in the near future. The simple use of language with a clear explanation of scientific terms, where applicable, makes this book an accessible source of information for anyone interested in enhancing their general knowledge about regenerative medicine when considering such treatment options and understanding the debate surrounding stem cell technology and its use in disease therapy.
| Author | : Suchandra Chowdhury |
| Publisher | : Springer Nature |
| Total Pages | : 271 |
| Release | : 2021-07-24 |
| Genre | : Science |
| ISBN | : 9811616388 |
Download Stem Cells Book in PDF, ePub and Kindle
Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem cells in regenerative medicine and therapy, and highlight their application in cancer therapy and spinal cord injury. The book talks about the important patents on stem cells. The book also highlights the plant stem cells, discussing their pluoripotent nature, role in organ regeneration after injury, specific stem cell niches, that signals to block differentiation studied in plants shoot, root, and vascular meristems, differentiation of plant stem cell, transcriptional regulation and epigenetic modification of plant stem cells. This book is exciting and cutting edge. It will be of great interest to doctors, students and researchers in the field of regenerative medicine, cancer , biotechnology and plant sciences.
| Author | : Michelle Ariana Wedemeyer |
| Publisher | : |
| Total Pages | : 198 |
| Release | : 2012 |
| Genre | : |
| ISBN | : 9781267346216 |
Download Regenerative Strategies in the Spinal Cord Book in PDF, ePub and Kindle
Populations of cells were obtained from a clinic offering "treatments" for chronic spinal cord injury. Immunostaining and flow cytometry confirmed the populations to be neural and mesenchymal stem cells, respectively (NSCs and MSCs). ELISAs performed on conditioned media detected several growth factors although neurotrophic factors known to promote regeneration in the spinal cord were not detected. Treatment of primary cortical neurons with media conditioned by MSCs and NSCs did not lead to a statistically significant increase in axon length or complexity. A statistically significant increase in cell number was detected in cultures treated with NSC-conditioned media. In vitro analysis does not support the clinic's claim that the cells exhibit properties which would promote axon growth. Two human embryonic stem cell lines (ES) and three induced pluripotent stem cell lines (iPS) were differentiated into high purity populations of neuronal progenitor cells (NPCs) and oligodendrocyte progenitor cells (OPCs). Both ES and two of three iPS lines produced high purity populations of the desired lineage. Transplantation of OPCs generated from ES and iPS lines into spinal cord injured rats resulted in engraftment of human oligodendrocytes without formation of tumors. We conclude that iPS cells may be adapted to protocols developed for generation of high purity NPCs and OPCs from ES cells. Immature astrocytes are known to promote recovery from spinal cord injury. In order to determine properties of immature astrocytes which promote recovery after spinal cord injury an in vitro model of aged astrocytes was developed. As compared to aged astrocytes, a greater proportion of immature astrocytes are proliferating, express more laminin, are motile, and promote greater regeneration of dorsal root ganglion (DRG) axons. Reprogramming mature astrocytes into immature astrocytes is a potential therapy for chronic spinal cord injury. Nine factors which are expressed at higher levels in immature versus mature astrocytes were overexpressed in aged astrocytes. At two weeks, treated cultures exhibited greater laminin immunofluorescence, increased capacity to promote growth of adult DRG axons, and foci of increased motility mixed with foci of cell death. Treatment of aged astrocytes with 9 factors leads to partial recovery of immature properties.
| Author | : Phuc Van Pham |
| Publisher | : Springer |
| Total Pages | : 316 |
| Release | : 2017-01-24 |
| Genre | : Science |
| ISBN | : 3319401440 |
Download Bone and Cartilage Regeneration Book in PDF, ePub and Kindle
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
| Author | : Ngan Huang |
| Publisher | : World Scientific |
| Total Pages | : 567 |
| Release | : 2017-11-24 |
| Genre | : Science |
| ISBN | : 9813147768 |
Download Engineering Stem Cells For Tissue Regeneration Book in PDF, ePub and Kindle
Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary.This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students.
| Author | : Alain A. Vertes |
| Publisher | : John Wiley & Sons |
| Total Pages | : 788 |
| Release | : 2015-12-02 |
| Genre | : Science |
| ISBN | : 111997139X |
Download Stem Cells in Regenerative Medicine Book in PDF, ePub and Kindle
This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.
