Recombinant and Synthetic Vaccines
Author | : |
Publisher | : |
Total Pages | : 512 |
Release | : 1994 |
Genre | : |
ISBN | : 9780387572574 |
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Author | : |
Publisher | : |
Total Pages | : 512 |
Release | : 1994 |
Genre | : |
ISBN | : 9780387572574 |
Author | : Dr. Ramesh C.K. |
Publisher | : Lulu.com |
Total Pages | : 178 |
Release | : 2017-02-14 |
Genre | : Education |
ISBN | : 1365707342 |
The immune system is a network of cells, tissues, and organs that work together to defend the body against attacks by "foreign" invaders. Invaders are primarily microbes such as bacteria, viruses, parasites and fungi. Because the human body provides an ideal environment for many microbes, they try to break in. It is the immune system's job to keep them out or, failing that, to seek out and destroy them. When the immune system hits the wrong target or is crippled, however, it can unleash seversl diseases, including allergy, arthritis or immune disorders.
Author | : Clarisa Beatriz Palatnik-de-Sousa |
Publisher | : Frontiers Media SA |
Total Pages | : 284 |
Release | : 2018-07-12 |
Genre | : Antigens |
ISBN | : 288945522X |
Author | : Maureen C. Ferran |
Publisher | : Humana |
Total Pages | : 0 |
Release | : 2017-04-04 |
Genre | : Medical |
ISBN | : 9781493968671 |
This volume provides readers with methods and protocols for understanding the development of recombinant viruses and their use as vaccines platforms. Recombinant Virus Vaccines: Methods and Protocols details the use of recombinant vaccines that are employed to either produce immunogens in vitro or elicit antibody production in vivo. The chapters in this book are divided into four parts: Part I explores double-stranded DNA viruses; Part II discusses negative sense single-stranded RNA viruses; Part III talks about positive sense single-stranded RNA viruses; and Part IV describes bacteriophages. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Recombinant Virus Vaccines: Methods and Protocols is a valuable resource for scientists and clinicians who are interested in learning about and adopting methods for use in basic and biomedical research directed toward generating and developing recombinant viral vaccines.
Author | : Richard Isaacson |
Publisher | : CRC Press |
Total Pages | : 432 |
Release | : 1992-07-21 |
Genre | : Medical |
ISBN | : 9780824786991 |
Author | : Matthew M. Binns |
Publisher | : CRC Press |
Total Pages | : 360 |
Release | : 1992-05-27 |
Genre | : Science |
ISBN | : 9780849361791 |
Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines. The book considers a wide range of issues involved in producing new genetically engineered live vaccines, such as efficacy, safety, stability, cost, host range, immune response, immunization route, use of multivalent vaccines, and need for revaccination. The opening chapter describes the origin of vaccinia virus, its use to eradicate smallpox, and the pathogenesis of poxvirus infections. Subsequent chapters examine the molecular biology of poxviruses, methods of constructing vaccinia virus recombinants, and applications; the use and immune responses induced by poxvirus recombinants as live vaccines; and the important issues of the safety and immunogenicity of vaccinia virus. The book's final two chapters report the progress that has been made developing avipoxviruses and parapoxviruses as candidate recombinant vaccines. Recombinant Poxviruses will be a welcome addition to the bookshelves of virologists, microbiologists, infectious disease specialists, and veterinarians.
Author | : Sara Cohen |
Publisher | : Springer Science & Business Media |
Total Pages | : 197 |
Release | : 2013-06-29 |
Genre | : Medical |
ISBN | : 1489913823 |
Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic instabilities, increase the needs for the development of new, advanced vaccines. In this volume, devoted to the proceedings of the 39th OHOLO Conference, we present some of the recent strategies for the design and production of novel vaccines. The advent of recombinant DNA technology has stimulated the production of several subunit vaccines. In spite of the obvious advantages to this approach, the limited immuno genicity of many subunit candidates has hindered their development. Strategies to enhance the immunogenicity of subunit vaccines is therefore critical. Several approaches toward this goal, including design of novel adjuvants and delivery systems as well as design of advantageous carriers, are presented here. Among the carriers evaluated here are polypep tides (flagellin, HBV core antigen, J3-galactosidase), attenuated virions (Vaccinia, Sindbis), and nonpathogenic licensed bacteria (Salmonella).
Author | : Willem Willie Overwijk |
Publisher | : |
Total Pages | : 288 |
Release | : 2001 |
Genre | : |
ISBN | : |
Author | : Daan J. A. Crommelin |
Publisher | : CRC Press |
Total Pages | : 456 |
Release | : 2002-11-14 |
Genre | : Medical |
ISBN | : 9780415285018 |
The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.
Author | : Matthias Giese |
Publisher | : Springer |
Total Pages | : 383 |
Release | : 2016-03-11 |
Genre | : Medical |
ISBN | : 331925832X |
This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.