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Radiofrequency Ablation for Small Hepatocellular Carcinoma

Radiofrequency Ablation for Small Hepatocellular Carcinoma
Author: Minshan Chen
Publisher: Springer
Total Pages: 110
Release: 2015-11-26
Genre: Medical
ISBN: 9401772584

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This book provides a comprehensive guide to the treatment of small hepatocellular carcinoma (sHCC) using a minimally invasive technique: radiofrequency ablation (RFA). RFA has emerged as a new treatment modality and become the main modality of locoregional therapy. Extensive clinical research indicates that RFA is as effective as surgical resection for sHCC, and it has the advantage of being less invasive. However, the outcomes after RFA are largely dependent on the operators’ experience- known as the “learning curve”. This book presents the characteristics of sHCC and discusses why sHCC is the best candidate for RFA. Then it introduces all the commercially available RFA systems, and their working principles, advantages, disadvantages and so on. It goes on to demonstrate how to perform RFA under the guidance of ultrasound, CT, laparoscopy, or during open operation. Finally, it discusses the radiologic assessment and follow‐up after RFA, as well as adjuvant therapies and clinical trials on RFA. The authors are experts from the fields of pathology, radiology, surgery, and gastroenterology, as well as manufacturers. With this book, readers gain have a clear idea of when and how to do RFA. It aims to standardize and generalize the procedure of RFA, which will be very helpful in improving the outcome of RFA for sHCC.


Hepatocellular Carcinoma

Hepatocellular Carcinoma
Author: Yujin Hoshida
Publisher: Springer
Total Pages: 366
Release: 2019-08-05
Genre: Medical
ISBN: 3030215407

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This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.


Liver Malignancies

Liver Malignancies
Author: C. Bartolozzi
Publisher: Springer Science & Business Media
Total Pages: 534
Release: 2012-12-06
Genre: Medical
ISBN: 3642586414

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A comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver malignancies. Following background chapters on anatomy, epidemiology, and clinicopathologic features, each of the diagnostic imaging techniques is carefully appraised, focusing on new developments in equipment and contrast agents. The interventional therapeutic approaches to primary and secondary hepatic malignancies are then discussed in depth, as well as such special topics as liver tumors in children and hepatic transplantation. Written by leading experts from around the world, this will prove to be an indispensable source of information for both clinicians and researchers.


Tumor Ablation

Tumor Ablation
Author: Eric van Sonnenberg
Publisher: Springer Science & Business Media
Total Pages: 554
Release: 2008-09-08
Genre: Medical
ISBN: 0387286748

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There is an enormous sense of excitement in the communities of cancer research and cancer care as we move into the middle third of the ?rst decade of the 21st century. For the ?rst time,there is a true sense of c- ?dence that the tools provided by the human genome project will enable cancer researchers to crack the code of genomic abnormalities that allow tumor cells to live within the body and provide highly speci?c, virtually non-toxic therapies for the eradication,or at least ?rm control of human cancers. There is also good reason to hope that these same lines of inquiry will yield better tests for screening, early detection, and prev- tion of progression beyond curability. While these developments provide a legitimate basis for much op- mism, many patients will continue to develop cancers and suffer from their debilitating effects, even as research moves ahead. For these in- viduals, it is imperative that the cancer ?eld make the best possible use of the tools available to provide present day cancer patients with the best chances for cure, effective palliation, or, at the very least, relief from symptoms caused by acute intercurrent complications of cancer. A modality that has emerged as a very useful approach to at least some of these goals is tumor ablation by the use of physical or physiochemical approaches.


Laser-induced Interstitial Thermotherapy

Laser-induced Interstitial Thermotherapy
Author: Gerhard J. Müller
Publisher: SPIE Press
Total Pages: 572
Release: 1995
Genre: Lasers in medicine
ISBN: 9780819418593

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Recurrence of Hepatocellular Carcinoma After Radiofrequency Ablation

Recurrence of Hepatocellular Carcinoma After Radiofrequency Ablation
Author: Eslam Habba
Publisher: LAP Lambert Academic Publishing
Total Pages: 204
Release: 2015-12-11
Genre:
ISBN: 9783659801990

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Hepatocellular carcinoma is a major health problem worldwide, with an estimated incidence ranging between 500,000 and 1,000,000 new cases annually. It is the fifth most common cancer in the world and the third most common cause of cancer-related deaths.For years, partial hepatectomy and liver transplantation have been considered as the main curative treatments. However, only 10% to 20% of HCC are resectable. Anatomic location, size or number of lesions, inadequate liver remnant, or co-morbid condition precludes surgery in the majority of patients. Currently, local ablative therapy competes with partial hepatectomy and liver transplantation as primary treatment for small HCC.Radiofrequency ablation (RFA) is considered a promising alternative to surgery. For irresectable tumors, RFA seems to be the most effective treatment among other locoregional therapies. The main advantages of RFA include low morbidity and mortality rates, effective tumor ablation and preservation of maximal normal liver parenchyma.However, despite the high complete necrosis rate of RFA, early tumor recurrence within one year, either local tumor recurrence or new tumor formation, remains a significant problem


Interventional Ultrasound

Interventional Ultrasound
Author: Hans Henrik Holm
Publisher: Springer
Total Pages: 186
Release: 2013-11-11
Genre: Medical
ISBN: 3662255308

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Modern sonography makes possible the detection of small and subtle changes in the normal echo pattern. These may represent significant pathological changes which can not al ways be fully revealed by the echo pattern alone. There is, therefore, an increasing need for the supplement of the ultra sonically guided percutaneous puncture, which can be per formed with great accuracy and with virtually no risk. Also, ultrasonically guided puncture has proven invaluable for a wide variety of therapeutic purposes. The first percutaneous puncture guided by ultrasonic scanning using a specifically designed transducer was per formed in 1969 at the ultrasonic laboratory in Gentofte, now Herlev, Hospital, Copenhagen. The idea was based on a punc ture transducer described and used by Kratochwill for punc ture under the guidance of the ultrasonic A-presentation tech nique. The development in the field formed the basis of the First International Conference on Ultrasonically Guided Puncture at Herlev Hospital in 1978 sponsored by The Danish Society of Diagnostic Ultrasound. The knowledge and experience of the speakers at that conference was compiled in the book "Ultrasonically Guided Puncture Technique" published in 1980. Since then the Society has sponsored a conference at the same place in 1980 and 1983, the latest conference being termed "Third International Conference on lnterventional Ultrasound".


Atlas of Upper Gastrointestinal and Hepato-Pancreato-Biliary Surgery

Atlas of Upper Gastrointestinal and Hepato-Pancreato-Biliary Surgery
Author: Pierre-Alain Clavien
Publisher: Springer Science & Business Media
Total Pages: 971
Release: 2007-09-13
Genre: Medical
ISBN: 3540688668

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This atlas covers in detail the technical aspects of all important procedures of the upper abdomen (esophagus, duodenum, stomach, liver, biliary system, pancreas, portal hypertension and spleen) including general, oncologic and transplantation surgery. Each procedure is associated with a short comment regarding indications of the various operative steps. Approximately 900 illustrations have been drawn by the same team of three artists of notable experience. The liver section follows the internationally accepted terminology of the Brisbane 2000 conference of the IHPBA. In this atlas experts of upper abdominal surgery share their experience step-by-step.


Focal Liver Lesions

Focal Liver Lesions
Author: Riccardo Lencioni
Publisher: Springer Science & Business Media
Total Pages: 397
Release: 2005-08-05
Genre: Medical
ISBN: 3540263543

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Few fields of medicine have witnessed such impressive progress as the diagnosis and treatment of liver tumors. Advances in imaging technology, the development of novel contrast agents, and the introduction of optimized scanning protocols have greatly facilitated the non-invasive detection and characterization of focal liver lesions. Furthermore, image-guided techniques for percutaneous tumor ablation have become an accepted alternative treatment for patients with inoperable liver cancer. This book provides a comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver tumors. The volume moves from background sections on methodology and segmental liver anatomy to the main sections on the diagnosis of benign and malignant liver lesions. An integrated approach, focused on the correlation of ultrasound, CT, and MR imaging findings, is presented. Finally, a full section describes the principles, methods, and results of percutaneous tumor ablation techniques.