Quantitative Methods In Pharmaceutical Research And Development PDF Download

Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Quantitative Methods In Pharmaceutical Research And Development PDF full book. Access full book title Quantitative Methods In Pharmaceutical Research And Development.

Quantitative Methods in Pharmaceutical Research and Development

Quantitative Methods in Pharmaceutical Research and Development
Author: Olga V. Marchenko
Publisher: Springer Nature
Total Pages: 445
Release: 2020-09-24
Genre: Medical
ISBN: 3030485552
GET BOOK

Download Quantitative Methods in Pharmaceutical Research and Development Book in PDF, ePub and Kindle

This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.

Drug Design Strategies

Drug Design Strategies
Author: David J. Livingstone
Publisher: Royal Society of Chemistry
Total Pages: 517
Release: 2012
Genre: Medical
ISBN: 1849731667
GET BOOK

Download Drug Design Strategies Book in PDF, ePub and Kindle

This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery process can be addressed in a quantitative fashion (ie: numerical analysis to enable robust predictions to be made). Each chapter includes a brief review of the topic showing the historical development of.

Statistical Methods for Pharmaceutical Research Planning

Statistical Methods for Pharmaceutical Research Planning
Author: S. W. Bergman
Publisher: CRC Press
Total Pages: 273
Release: 2020-10-29
Genre: Mathematics
ISBN: 1000148734
GET BOOK

Download Statistical Methods for Pharmaceutical Research Planning Book in PDF, ePub and Kindle

This book focuses on statistical methods which impinge more or less directly on the decisions that are made during the course of pharmaceutical and agro-chemical research, considering the four decision-making areas.

Statistical Development of Quality in Medicine

Statistical Development of Quality in Medicine
Author: Per Winkel
Publisher: John Wiley & Sons
Total Pages: 280
Release: 2007-06-13
Genre: Mathematics
ISBN: 9780470515891
GET BOOK

Download Statistical Development of Quality in Medicine Book in PDF, ePub and Kindle

The promotion of standards and guidelines to advance quality assurance and control is an integral part of the health care sector. Quantitative methods are needed to monitor, control and improve the quality of medical processes. Statistical Development of Quality in Medicine presents the statistical concepts behind the application of industrial quality control methods. Filled with numerous case studies and worked examples, the text enables the reader to choose the relevant control chart, to critically apply it, improve it if necessary, and monitor its stability. Furthermore, the reader is provided with the necessary background to critically assess the literature on the application of control charts and risk adjustment and to apply the findings. Contains a user-friendly introduction, setting out the necessary statistical concepts used in the field. Uses numerous real-life case studies from the literature and the authors’ own research as the backbone of the text. Provides a supplementary website featuring problems and answers drawn from the book, alongside examples in Statgraphics. The accessible style of Statistical Development of in Clinical Medicine invites a large readership. It is primarily aimed at health care officials, and personnel responsible for developing and controlling the quality of health care services. However, it is also ideal for statisticians working with health care problems, diagnostic and pharmaceutical companies, and graduate students of quality control.

Quantitative Methods in System-Based Drug Discovery

Quantitative Methods in System-Based Drug Discovery
Author: Yuzhen Luo
Publisher:
Total Pages:
Release: 2016
Genre: Technology
ISBN:
GET BOOK

Download Quantitative Methods in System-Based Drug Discovery Book in PDF, ePub and Kindle

Modern pharmaceutical industries have faced significant challenges to deliver safe and effective medicines because of significant toxicity and severe side effects of discovered drugs. On the other hand, recent developments and advances in system-based pharmacology aim to address these challenges. In this chapter, we provide an overview of quantitative methods for system-based drug discovery. System-based drug discovery integrates chemical, molecular, and systematic information and applies this knowledge to the designing of small molecules with controlled toxicity and minimized side effects. First, we discuss current approaches for drug discovery and outline their advantages and disadvantages. Next, we introduce basic concepts of systems pharmacology with an emphasis on ligand-based drug discovery and target identification. This is followed by a discussion on structure-based drug design and statistical tools for pharmaceutical research. Finally, we provide an overview of future directions in systems pharmacology that will guide further developments.

Research Methods in Pharmacy Practice

Research Methods in Pharmacy Practice
Author: Zubin Austin
Publisher: Elsevier Health Sciences
Total Pages: 280
Release: 2018-02-21
Genre: Medical
ISBN: 070207425X
GET BOOK

Download Research Methods in Pharmacy Practice Book in PDF, ePub and Kindle

This is a comprehensive guide to applying research methods to practice problems. It uses case-based examples and activities rooted in practice to support development of knowledge, skills, and confidence in applying evidence-based research methods. An array of different methodologies and qualitative/quantitative methods are described. Examples of topics include distinction between methodologies and methods, ethics protocols, as well as design/implementation/data analysis/interpretation of findings using methods such as surveys, interviews, focus groups, observational research, database mining, text and document analysis, quality improvement (PDSA cycles), economic (cost/benefit) evaluations. Perfect for MPharm students doing their research thesis, but relevant to all bioscience students undertaking research projects. Use of pharmacy practice case examples (in community, hospital, ambulatory, primary care and other settings) throughout. Examples of how to tackle a research question from different perspectives, e.g. which is the best way to answer each question and why. Inter-professional practice and research emphasized. Self-assessment and self-reflection questions to help readers confirm their understanding/learning. A one-stop research-method teaching resource for faculty.

Computer Applications in Pharmaceutical Research and Development

Computer Applications in Pharmaceutical Research and Development
Author: Sean Ekins
Publisher: John Wiley & Sons
Total Pages: 840
Release: 2006-07-11
Genre: Medical
ISBN: 0470037229
GET BOOK

Download Computer Applications in Pharmaceutical Research and Development Book in PDF, ePub and Kindle

A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

Quantitative Calculations in Pharmaceutical Practice and Research

Quantitative Calculations in Pharmaceutical Practice and Research
Author: Themistoklēs P. Chatzēiōannou
Publisher: VCH Publishers
Total Pages: 488
Release: 1993
Genre: Medical
ISBN:
GET BOOK

Download Quantitative Calculations in Pharmaceutical Practice and Research Book in PDF, ePub and Kindle

This practical handbook aims at familiarizing students and scientists with the most common calculations encountered in the pharmaceutical sciences. It consolidates theoretical knowledge by applying it to the solution of real problems. Each chapter provides a short introduction of the relevant theory and includes equations to aid the comprehension of the theoretical principle. The text includes 220 solved examples and 250 problems and answers. Annotation copyright by Book News, Inc., Portland, OR

Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery

Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
Author: Gus R. Rosania
Publisher: Humana
Total Pages: 453
Release: 2021-07-12
Genre: Medical
ISBN: 9781071612491
GET BOOK

Download Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery Book in PDF, ePub and Kindle

This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the Methods in Pharmacology and Toxicology series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from reading this book or from using it as a textbook. Authoritative and practical, Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery builds on a long history of drug development and the adding of quantitative methods at the cellular scale in order to inspire new approaches to drug development that are better able to take advantage of phenomena such as soluble-to-insoluble phase transitions or bispecific targeting, which could ultimately be exploited for the development of more effective drug delivery systems and therapeutic agents.

Quantitative Evaluation of Safety in Drug Development

Quantitative Evaluation of Safety in Drug Development
Author: Qi Jiang
Publisher: CRC Press
Total Pages: 386
Release: 2014-12-08
Genre: Mathematics
ISBN: 1466555459
GET BOOK

Download Quantitative Evaluation of Safety in Drug Development Book in PDF, ePub and Kindle

State-of-the-Art Methods for Drug Safety Assessment Responding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product development. It presents the latest statistical methods for drug safety assessment. The book’s three sections focus on study design, safety monitoring, and data evaluation/analysis. The book addresses key challenges across regulatory agencies, industry, and academia. It discusses quantitative approaches to safety evaluation and risk management in drug development, covering Bayesian methods, effective safety graphics, and risk-benefit evaluation. Written by a team of experienced leaders, this book brings the most advanced knowledge and statistical methods of drug safety to the statistical, clinical, and safety community. It shares best practices and stimulates further research and methodology development in the drug safety area.