Proteins In Solution And At Interfaces PDF Download
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| Author | : Juan M. Ruso |
| Publisher | : John Wiley & Sons |
| Total Pages | : 823 |
| Release | : 2013-01-31 |
| Genre | : Science |
| ISBN | : 1118523172 |
Download Proteins in Solution and at Interfaces Book in PDF, ePub and Kindle
Explores new applications emerging from our latest understanding of proteins in solution and at interfaces Proteins in solution and at interfaces increasingly serve as the starting point for exciting new applications, from biomimetic materials to nanoparticle patterning. This book surveys the state of the science in the field, offering investigators a current understanding of the characteristics of proteins in solution and at interfaces as well as the techniques used to study these characteristics. Moreover, the authors explore many of the new and emerging applications that have resulted from the most recent studies. Topics include protein and protein aggregate structure; computational and experimental techniques to study protein structure, aggregation, and adsorption; proteins in non-standard conditions; and applications in biotechnology. Proteins in Solution and at Interfaces is divided into two parts: Part One introduces concepts as well as theoretical and experimental techniques that are used to study protein systems, including X-ray crystallography, nuclear magnetic resonance, small angle scattering, and spectroscopic methods Part Two examines current and emerging applications, including nanomaterials, natural fibrous proteins, and biomolecular thermodynamics The book's twenty-three chapters have been contributed by leading experts in the field. These contributions are based on a thorough review of the latest peer-reviewed findings as well as the authors' own research experience. Chapters begin with a discussion of core concepts and then gradually build in complexity, concluding with a forecast of future developments. Readers will not only gain a current understanding of proteins in solution and at interfaces, but also will discover how theoretical and technical developments in the field can be translated into new applications in material design, genetic engineering, personalized medicine, drug delivery, biosensors, and biotechnology.
| Author | : D. Möbius |
| Publisher | : Elsevier |
| Total Pages | : 509 |
| Release | : 1998-04-24 |
| Genre | : Science |
| ISBN | : 0080540007 |
Download Proteins at Liquid Interfaces Book in PDF, ePub and Kindle
The interfacial behaviour of surfactants and proteins, and their mixtures, is of importance in a wide range of areas such as food technology, detergency, cosmetics, coating processes, biomedicine, pharmacy and biotechnology. Methods such as surface and interfacial tension measurements and interfacial dilation and shear rheology characterise the relationships between these interfacial properties and the complex behaviour of foams and emulsions is established. Recently-developed experimental techniques, such as FRAP which enable the measurement of molecular mobility in adsorption layers, are covered in this volume. The development of theories to describe the thermodynamic surface state or the exchange of matter for proteins and protein/surfactant mixtures is also described. Features of this book: • Reflects the state-of-the-art research and application of protein interfacial layers rather than a snapshot of only some recent developments. • Emphasis is placed on experimental details as well as recent theoretical developments. • New experimental techniques applied to protein interfacial layers are described, such as FRAP or ADSA, or rheological methods to determine the mechanical behaviour of protein-modified interfaces. • A large number of practical applications, ranging from emulsions relevant in food technology for medical problems such as lung surfactants, to the characterisation of foams intrinsic to beer and champagne production. The book will be of interest to research and university institutes dedicated to interfacial studies in chemistry, biology, pharmacy, medicine and food engineering. Industrial departments for research and technology in food industry, pharmacy, medicine and brewery research will also find this volume of value.
| Author | : Philippe Déjardin |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 341 |
| Release | : 2006-09-28 |
| Genre | : Science |
| ISBN | : 3540326588 |
Download Proteins at Solid-Liquid Interfaces Book in PDF, ePub and Kindle
This book opens with a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. Presented here are methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS). Also described are sensitive bench techniques for measuring the orientation and structure of proteins at solid-liquid interfaces, including total internal reflection ellipsometry (TIRE), dual polarisation interferometry (DPI) and time of flight - secondary ion mass spectrometry (TOF–SIMS). A model study of fibronectin at polymer surfaces is included, as are studies using microporous membranes and textiles with immobilized enzymes for large-scale applications. Biocompatibility, anti-fouling properties and surface modification to modulate the adsorption and activity of biomolecules are among the other topics addressed in this invaluable book.
| Author | : Dorothy Jordan Lloyd |
| Publisher | : |
| Total Pages | : 302 |
| Release | : 1926 |
| Genre | : Proteins |
| ISBN | : |
Download Chemistry of the Proteins and Its Economic Applications Book in PDF, ePub and Kindle
| Author | : Derek J. Chadwick |
| Publisher | : John Wiley & Sons |
| Total Pages | : 282 |
| Release | : 2008-04-30 |
| Genre | : Science |
| ISBN | : 0470514159 |
Download Protein Conformation Book in PDF, ePub and Kindle
How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in the fields of NMR spectroscopy, X-ray crystallography, protein engineering and molecular modeling offer provocative insights into current views on the protein folding problem and various aspects for future progress.
| Author | : Jinjiang Li |
| Publisher | : Springer Nature |
| Total Pages | : 338 |
| Release | : 2021-02-12 |
| Genre | : Medical |
| ISBN | : 3030571777 |
Download Protein Instability at Interfaces During Drug Product Development Book in PDF, ePub and Kindle
Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.
| Author | : Christina Regina Vessely |
| Publisher | : |
| Total Pages | : 346 |
| Release | : 2006 |
| Genre | : |
| ISBN | : |
Download Effects of Solution Parameters on the Adsorption of Proteins at Interfaces Book in PDF, ePub and Kindle
| Author | : G. I. Loeb |
| Publisher | : |
| Total Pages | : 50 |
| Release | : 1965 |
| Genre | : Amino acids |
| ISBN | : |
Download Surface Chemistry of Proteins and Polypeptides Book in PDF, ePub and Kindle
The report is a review of recent literature in the field of polypeptide and protein surface chemistry, concentrating on the last decade. Theoretical approaches to polymers at liquid interfaces are considered, and surface measurement techniques are briefly outlined. The various classes of polypeptides are considered, followed by a discussion of proteins in general and specific proteins in particular. Enzymatic activity, structure, and adsorption at various surfaces are considered also. (Author).
| Author | : Hans Neurath |
| Publisher | : Elsevier |
| Total Pages | : 857 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0323161308 |
Download The Proteins Composition, Structure, and Function V2 Book in PDF, ePub and Kindle
The Proteins: Composition, Structure, and Function, Second Edition, Volume II deals with fundamental properties of proteins, both in solution and in the solid state. This volume consists of five chapters that specifically cover the advances in understanding the structure and function of the protein molecule. The opening chapter presents interpretative procedures of experimental methods for determining protein conformation using X-ray crystallography, followed by an examination of the acid-base dissociations of proteins. The discussion then shifts to the investigation of interactions between protein molecules and other macromolecules, which is of significant importance in providing a chemical basis for many biological processes. A chapter considers first the synthesis, purification, and chemical properties of the polyamino acids. This chapter further describes their physicochemical properties in the solid state, in solution, and at interfaces, and lastly discusses their biological properties as high molecular weight substrates for proteolytic enzymes and as synthetic antigens, and their interaction with proteins and nucleic acids, with viruses, bacteria, blood components, and other biological systems. The use of polyamino acids in the study of the genetic code and the preparation and properties of polypeptidyl proteins are also covered. The concluding chapter focuses on X-ray analysis of protein structure. Organic chemists, biochemists, and researchers in protein-related fields will find this book invaluable
| Author | : Haian Fu |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 525 |
| Release | : 2008-02-03 |
| Genre | : Science |
| ISBN | : 1592597629 |
Download Protein'Protein Interactions Book in PDF, ePub and Kindle
As the mysteries stored in our DNA have been more completely revealed, scientists have begun to face the extraordinary challenge of unraveling the int- cate network of protein–protein interactions established by that DNA fra- work. It is increasingly clear that proteins continuously interact with one another in a highly regulated fashion to determine cell fate, such as proliferation, diff- entiation, or death. These protein–protein interactions enable and exert str- gent control over DNA replication, RNA transcription, protein translation, macromolecular assembly and degradation, and signal transduction; essentially all cellular functions involve protein–protein interactions. Thus, protein–p- tein interactions are fundamental for normal physiology in all organisms. Alt- ation of critical protein–protein interactions is thought to be involved in the development of many diseases, such as neurodegenerative disorders, cancers, and infectious diseases. Therefore, examination of when and how protein–p- tein interactions occur and how they are controlled is essential for understa- ing diverse biological processes as well as for elucidating the molecular basis of diseases and identifying potential targets for therapeutic interventions. Over the years, many innovative biochemical, biophysical, genetic, and computational approaches have been developed to detect and analyze p- tein–protein interactions. This multitude of techniques is mandated by the diversity of physical and chemical properties of proteins and the sensitivity of protein–protein interactions to cellular conditions.
