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Principles and Practice of Bioanalysis

Principles and Practice of Bioanalysis
Author: Richard F. Venn
Publisher: CRC Press
Total Pages: 340
Release: 2008-02-25
Genre: Medical
ISBN: 142000560X

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In the seven years since the publication of Principles and Practice of Bioanalysis bioanalytical methods have remained the same, but their usage patterns have changed. This second edition of a bestseller provides an updated guide to the techniques used in developing and running ultra-trace analyses for drugs, metabolites, and other substance


Principles and Practice of Bioanalysis

Principles and Practice of Bioanalysis
Author: Richard F. Venn
Publisher: CRC Press
Total Pages: 392
Release: 2000-06-22
Genre: Medical
ISBN: 9780748408429

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Principles and Practice of Bioanalysis provides a guide to the methods available and the techniques currently used in this field. It provides up to the minute information and guidance on the methods and strategy used in developing and running ultra-trace analyses for drugs, metabolites and other substances. The authors writes in an informal and didactic style, offering a logical path through the problems of small molecule (bio)analysis and enables readers to choose appropriate methods of analysis for their needs. Principles and Practice of Bioanalysis provides an overview of analytical methods for analytical scientists within the pharmaceutical industry, research and development, the agrochemical industry, and scientists in the health service, biology and biochemistry. It also gives postgraduate students a useful reference for their research methods.


Principles and Practice of Bioanalysis, Second Edition

Principles and Practice of Bioanalysis, Second Edition
Author: Richard F. Venn
Publisher: CRC Press
Total Pages: 344
Release: 2008-02-25
Genre: Medical
ISBN: 9780849338571

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In the seven years since the publication of Principles and Practice of Bioanalysis bioanalytical methods have remained the same, but their usage patterns have changed. This second edition of a bestseller provides an updated guide to the techniques used in developing and running ultra-trace analyses for drugs, metabolites, and other substances. Extensively revised, this volume reflects the dynamic growth in methodologies that has occurred over the past five years. Each chapter has been overhauled or re-written to reflect modern practice. Experts in the field offer a logical path through the problems of small molecule bioanalysis, enabling you to choose the appropriate methods of analysis across a number of fields, including the agrochemical and pharmaceutical industries. They cover a wide range of analytical methods, including mass spectrometry, liquid chromatography, immunoassay, NMR, and gas chromatography. Presenting the information in an informal and highly accessible style, the book covers the theory and practice of bioanalysis, enabling you to gain maximum benefit and to optimize analytical methods. With practical advice and guidance, it delineates how to develop robust analytical methods for a range of compounds, both natural and synthetic. Using these insights, you can more easily recognize problems and quickly solve them.


Handbook of LC-MS Bioanalysis

Handbook of LC-MS Bioanalysis
Author: Wenkui Li
Publisher: John Wiley & Sons
Total Pages: 709
Release: 2013-09-03
Genre: Science
ISBN: 111867135X

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Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.


Regulated Bioanalysis: Fundamentals and Practice

Regulated Bioanalysis: Fundamentals and Practice
Author: Mario L. Rocci Jr.
Publisher: Springer
Total Pages: 239
Release: 2017-04-24
Genre: Medical
ISBN: 3319548026

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The editors have engaged leading scientists in the field to participate in the development of this book, which is envisioned as a “one of a kind” contribution to the field. The book is a comprehensive text that puts fundamental bioanalytical science in context with current practice, its challenges and ongoing developments. It expands on existing texts on the subject by covering regulated bioanalysis of both small and large molecule therapeutics from both a scientific and regulatory viewpoint. The content will be useful to a wide spectrum of readers: from those new to bioanalysis; to those developing their experience in the laboratory, or working in one of the many critical supporting roles; to seasoned practitioners looking for a solid source of information on this exciting and important discipline.


Tools and Trends in Bioanalytical Chemistry

Tools and Trends in Bioanalytical Chemistry
Author: Lauro Tatsuo Kubota
Publisher: Springer Nature
Total Pages: 559
Release: 2021-11-25
Genre: Science
ISBN: 3030823814

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This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.


Understanding Bioanalytical Chemistry

Understanding Bioanalytical Chemistry
Author: Victor A. Gault
Publisher: John Wiley & Sons
Total Pages: 258
Release: 2013-04-22
Genre: Science
ISBN: 1118684893

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"The title captures the ethos and content precisely. It brings basic chemistry into real life with examples that illustrate how chemical principals are inherent to bioanalytical procedures, making them accessible to readers with a background in life sciences." –Microbiology Today, July 2009 “... a good overview of the basic strategies to tackle the complexity of analysis in biological environments and provides some illustrative examples for a better understanding of the theoretical concepts... provides a fundamental introduction to the tools adopted by life and health scientists in the evolving and exciting new age of “omics” specifically applied to the diagnosis, treatment, cure and prevention of disease...” –Analytical and Bioanalytical Chemistry, October 2009 Although chemistry is core to the life and health sciences, it is often viewed as a challenging subject. Conventional textbooks tend to present chemistry in a way that is not always easily accessible to students, particularly those coming from diverse educational backgrounds, who may not have formally studied chemistry before. This prompted the authors to write this particular textbook, taking a new, fresh and innovative approach to teaching and learning of chemistry, focusing on bioanalysis to set knowledge in context. This textbook is primarily targeted to undergraduate life and health science students, but may be a useful resource for practising scientists in a range of disciplines. In this textbook the authors have covered basic principles, terminology and core technologies, which include key modern experimental techniques and equipment used to analyse important biomolecules in diagnostic, industrial and research settings. Written by two authors with a wealth of experience in teaching, research and academic enterprise, this textbook represents an invaluable tool for students and instructors across the diverse range of biological and health science courses. Key Features: Innovative, stand alone teaching and learning resource to enhance delivery of undergraduate chemistry provision to life and health scientists. Develops student knowledge and understanding of core concepts with reference to relevant, real-life, examples. Clearly written and user-friendly, with numerous full colour illustrations, annotated images, diagrams and tables to enhance learning. Incorporates a modern approach to teaching and learning to motivate the reader and encourage student-centred learning. Dr Victor Gault has been named recipient of the Rising Star Award 2009 by the internationally acclaimed European Association for the Study of Diabetes (EASD).


Introduction To Principles And Practice Of Respiratory Medicine, An: Theory To Bedside

Introduction To Principles And Practice Of Respiratory Medicine, An: Theory To Bedside
Author: Pa Mahesh
Publisher: World Scientific
Total Pages: 1159
Release: 2023-08-22
Genre: Medical
ISBN: 9811271429

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An Introduction to Principles and Practice of Respiratory Medicine is intended to be the first book read by postgraduates in Respiratory and Internal Medicine. It represents a broad spectrum of issues relevant to the clinician involved in managing respiratory diseases. There is material for the basic researcher as well as extensive material for the clinicians. This textbook will appeal to both graduate and postgraduate students in Respiratory Medicine, academicians and the clinicians managing patients in their day-to-day practice.A broad spectrum of issues in Respiratory Medicine is covered. The chapter on chest imaging is extensive with more than 100 illustrations in a single chapter and outlines new directions for the clinicians to approach interpretations of images. Airway diseases section is equally extensive with few chapters using the case-based problem-solving approach for easier understanding. A comprehensive overview of the respiratory system is presented thus making it easy to read and understand.


Principles and Practice of Forensic Psychiatry

Principles and Practice of Forensic Psychiatry
Author: Richard Rosner
Publisher: CRC Press
Total Pages: 1097
Release: 2017-02-03
Genre: Law
ISBN: 1482262290

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The third edition of this award-winning textbook has been revised and thoroughly updated. Building on the success of the previous editions, it continues to address the history and practice of forensic psychiatry, legal regulation of the practice of psychiatry, forensic evaluation and treatment, psychiatry in relation to civil law, criminal law and family law, as well as correctional forensic psychiatry. New chapters address changes in the assessment and treatment of aggression and violence as well as psychological and neuroimaging assessments.


The Handbook of Medicinal Chemistry: Principles and Practice

The Handbook of Medicinal Chemistry: Principles and Practice
Author: Simon E Ward
Publisher: Royal Society of Chemistry
Total Pages: 1051
Release: 2023-02-03
Genre: Medical
ISBN: 1788018982

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The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.