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Poisonous Plants and Phytochemicals in Drug Discovery

Poisonous Plants and Phytochemicals in Drug Discovery
Author: Andrew G. Mtewa
Publisher: John Wiley & Sons
Total Pages: 432
Release: 2020-12-04
Genre: Science
ISBN: 1119650275

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Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery - Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery - Written and edited by leading researchers in phytochemistry, medicinal chemistry, analytical chemistry, toxicology, and more - Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career


Plant Toxins

Plant Toxins
Author: P. Gopalakrishnakone
Publisher:
Total Pages:
Release:
Genre: Plant toxins
ISBN: 9789400767287

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Chemistry of Natural Products

Chemistry of Natural Products
Author: Mayuri Napagoda
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 302
Release: 2022-04-19
Genre: Science
ISBN: 3110593653

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Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques. This book is ideal for researchers in the areas of biochemistry, medicine, and pharmacology.


Bioactive Phytochemicals

Bioactive Phytochemicals
Author: Javed Ahamad
Publisher:
Total Pages: 238
Release: 2020-10-28
Genre:
ISBN: 9789811464478

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Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural compounds from their plant sources with the goal of treating specific diseases. Bioactive Phytochemicals: Drug Discovery to Product Development explores the scope and approaches of drug discovery from natural products. Chapters in the book cover information about the cultivation, collection and processing of medicinal plants, the methods and high throughput techniques for isolation and characterization of bioactive phytochemicals and pharmacological screening for activity, formulation and quality control. Information about the regulations specified for natural medicinal products in different region of the world is also presented, followed by a concluding chapter devoted to the role of natural herbal products for treatment of human diseases such as cancer, cardiovascular diseases, diabetes, obesity, inflammation and neurological disorders. Each chapter concludes with a general reference section, which is a bibliographic guide to more advanced texts. The contributing authors for this volume are drawn from a rich blend of experts in various areas of herbal medicine which encompass herbal drug discovery to product development. The concise and organized layout along with a broad coverage of phytochemistry and drug discovery makes this book a suitable reference for students of medicinal chemistry, researchers and industry professionals interested in herbal product development.


Poisonous Plants and Phytochemicals in Drug Discovery

Poisonous Plants and Phytochemicals in Drug Discovery
Author: Andrew G. Mtewa
Publisher: John Wiley & Sons
Total Pages: 432
Release: 2020-12-04
Genre: Science
ISBN: 1119650259

Download Poisonous Plants and Phytochemicals in Drug Discovery Book in PDF, ePub and Kindle

Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery - Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery - Written and edited by leading researchers in phytochemistry, medicinal chemistry, analytical chemistry, toxicology, and more - Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career


Exploring Poisonous Plants

Exploring Poisonous Plants
Author: Azamal Husen
Publisher: CRC Press
Total Pages: 525
Release: 2023-03-14
Genre: Health & Fitness
ISBN: 1000834409

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Poisonous plants are used in traditional medicine systems in various healing therapies. They are a rich resource of ingredients used in herbal drug formulations that are also used in the development of synthetic drugs. They are recognized for their antioxidant, anti-inflammation, anti-cancer, and anti-diabetic activities and for many other health benefits. Exploring Poisonous Plants: Medicinal Values, Toxicity Responses, and Therapeutic Uses provides an analysis of the most important poisonous herbs, shrubs, and trees, detailing poisonous plants while demonstrating endorsements for their potential therapeutic values. Features: Presents therapeutic potentials on various poisonous herbs, shrubs, and trees. Provides descriptions of notable toxic compounds and discusses their adverse effects when consumed by animals or people. Gives practical guidance for botanical description, distribution, phytochemical constituents, pharmacological studies, and traditional and other potential uses of selected poisonous plants. This volume in the Exploring Medicinal Plants series is appropriate for scientists, researchers, and students working with poisonous plants, as well as in areas of economic botany, plant biochemistry, biotechnology, pharmacognosy, pharmaceuticals, industrial chemistry, and nanomedicine.


Toxicological Survey of African Medicinal Plants

Toxicological Survey of African Medicinal Plants
Author: Victor Kuete
Publisher: Elsevier
Total Pages: 742
Release: 2014-05-30
Genre: Medical
ISBN: 0128004754

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Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology


Phytochemistry of Medicinal Plants

Phytochemistry of Medicinal Plants
Author: John T. Arnason
Publisher: Springer Science & Business Media
Total Pages: 369
Release: 2013-11-11
Genre: Science
ISBN: 1489917780

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Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.


Drug Discovery and Development

Drug Discovery and Development
Author: Ramarao Poduri
Publisher: Springer Nature
Total Pages: 522
Release: 2021-02-15
Genre: Medical
ISBN: 9811555346

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This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.


Therapeutic Use of Medicinal Plants and their Extracts: Volume 2

Therapeutic Use of Medicinal Plants and their Extracts: Volume 2
Author: A.N.M. Alamgir
Publisher: Springer
Total Pages: 0
Release: 2019-02-14
Genre: Medical
ISBN: 9783030064235

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This book starts with a general introduction to phytochemistry, followed by chapters on plant constituents, their origins and chemistry, but also discussing animal-, microorganism- and mineral-based drugs. Further chapters cover vitamins, food additives and excipients as well as xenobiotics and poisons. The book also explores the herbal approach to disease management and molecular pharmacognosy and introduces methods of qualitative and quantitative analysis of plant constituents. Phytochemicals are classified as primary (e.g. carbohydrates, lipids, amino acid derivations, etc.) or secondary (e.g. alkaloids, terpenes and terpenoids, phenolic compounds, glycosides, etc.) metabolites according to their metabolic route of origin, chemical structure and function. A wide variety of primary and secondary phytochemicals are present in medicinal plants, some of which are active phytomedicines and some of which are pharmaceutical excipients.