Pharmacogenomics And Precision Medicine An Issue Of The Clinics In Laboratory Medicine PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Pharmacogenomics And Precision Medicine An Issue Of The Clinics In Laboratory Medicine PDF full book. Access full book title Pharmacogenomics And Precision Medicine An Issue Of The Clinics In Laboratory Medicine.
| Author | : Kristen Reynolds |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 177 |
| Release | : 2016-08-16 |
| Genre | : Medical |
| ISBN | : 0323462804 |
Download Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine Book in PDF, ePub and Kindle
This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.
| Author | : Ryan J. Schmidt |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 129 |
| Release | : 2020-06-21 |
| Genre | : Medical |
| ISBN | : 0323758460 |
Download Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, An Issue of the Clinics in Laboratory Medicine Book in PDF, ePub and Kindle
This issue of Clinics in Laboratory Medicine will cover Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies. Curated by Dr. Ryan J. Schmidt, this issue is one of four selected each year by the series Consulting Editor, Milenko Tanasijevic. The volume will include articles on: Features of a Comprehensive Precision Medicine Program for Constitutional Genetic Disorders, Establishing a Precision Medicine Center of Excellence for Rare Disease, High-throughput DNA Sequencing for Rare Disease Diagnosis, Enhancing Diagnosis through RNA Sequencing, Interpretation of Rare Genetic Variants, Clinical Bioinformatics, Precision Therapies for Retinal Dystrophy, Precision Therapies for Muscular Dystrophy, Therapeutic Gene Editing, High Throughput Functional Studies of Genetic Variants, and Patient-specific Disease Models.
| Author | : Gregory J. Tsongalis |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 217 |
| Release | : 2022-11-12 |
| Genre | : Medical |
| ISBN | : 0443183112 |
Download Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book Book in PDF, ePub and Kindle
In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
| Author | : Gregory J. Tsongalis |
| Publisher | : Elsevier |
| Total Pages | : 0 |
| Release | : 2022-11-16 |
| Genre | : Medical |
| ISBN | : 9780443183102 |
Download Current Topics in Molecular Diagnostics and Precision Medicine, an Issue of the Clinics in Laboratory Medicine: Volume 42-4 Book in PDF, ePub and Kindle
In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
| Author | : Alan H. B. Wu |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 276 |
| Release | : 2011-02-08 |
| Genre | : Medical |
| ISBN | : 1607612836 |
Download Pharmacogenomic Testing in Current Clinical Practice Book in PDF, ePub and Kindle
While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.
| Author | : Kristen K. Reynolds |
| Publisher | : W B Saunders Company |
| Total Pages | : 240 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 9781416063131 |
Download Pharmacogenetics Book in PDF, ePub and Kindle
Applications in Pharmacogenetics are breaching the laboratory medicine and clinical environment. The testing of genetic variations in relation to differing response to drug metabolism and improvement of drug safety is an important and essential area in light of adverse drug reactions. This timely and comprehensive issue of the Clinics presents topics related to Pharmacology and Genetics, Pharmacogenetic Applications in Anticoagulation, Oncology, Pain Management, and Behavioral Disorders, Respiratory Disorders, as well as Education and Healthcare Economics of Pharmacogenetics.
| Author | : Loralie J. Langman |
| Publisher | : John Wiley & Sons |
| Total Pages | : 400 |
| Release | : 2012-01-09 |
| Genre | : Medical |
| ISBN | : 1119959586 |
Download Pharmacogenomics in Clinical Therapeutics Book in PDF, ePub and Kindle
Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring. Pharmacogenomics in Clinical Therapeutics provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug–drug interactions. From a team of expert contributors, Pharmacogenomics in Clinical Therapeutics is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.
| Author | : Amitava Dasgupta |
| Publisher | : CRC Press |
| Total Pages | : 252 |
| Release | : 2019-08-30 |
| Genre | : |
| ISBN | : 9780367381493 |
Download Pharmacogenomics of Alcohol and Drugs of Abuse Book in PDF, ePub and Kindle
Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy. Applying these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.
| Author | : Weimin Cai |
| Publisher | : Springer Nature |
| Total Pages | : 290 |
| Release | : 2020-06-12 |
| Genre | : Medical |
| ISBN | : 9811538956 |
Download Pharmacogenomics in Precision Medicine Book in PDF, ePub and Kindle
This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
| Author | : Rongling Wu |
| Publisher | : C&h/CRC Press |
| Total Pages | : 0 |
| Release | : 2022-12 |
| Genre | : Personalized medicine |
| ISBN | : 9781032398877 |
Download Quantitative Methods for Precision Medicine Book in PDF, ePub and Kindle
"Modern medicine is undergoing a paradigm shift from a "one-size-fits-all" strategy to a more precise patient-customized therapy and medication plan. While the success of precision medicine relies on the level of pharmacogenomic knowledge, dissecting the genetic mechanisms of drug response in a sufficient detail requires powerful computational tools. Quantitative Methods for Precision Medicine: Pharmacogenomics in Action presents the advanced statistical methods for mapping pharmacogenetic control by integrating pharmacokinetic and pharmacodynamic principles of drug-body interactions. Beyond traditional reductionist-based statistical genetic approaches, statistical formulization in this book synthesizes elements of multiple disciplines to infer, visualize, and track how pharmacogenes interact together as an intricate but well-coordinated system to mediate patient-specific drug response. Features: Functional and systems mapping models to characterize the genetic architecture of multiple medication processes Statistical methods for analyzing informative missing data in pharmacogenetic association studies Functional graph theory of inferring genetic interaction networks from association data Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties Modeling gene-induced cell-cell crosstalk and its impact on drug response A graph model of drug-drug interactions in combination therapies Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine This book is suitable for graduate students and researchers in the field of biology, medicine, bioinformatics and drug design and delivery interested in statistical and computational modelling of biological processes and systems. It may also serve as a major reference for applied mathematicians, computer scientists, and statisticians who attempt to develop algorithmic tools for genetic mapping, systems pharmacogenomics and systems biology. It can be used as both a textbook and research reference. It can also be used by professionals in pharmaceutical sectors who design drugs and by clinical doctors who deliver drugs"--
