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Pharmacodynamic Basis of Herbal Medicine

Pharmacodynamic Basis of Herbal Medicine
Author: Manuchair Ebadi
Publisher: CRC Press
Total Pages: 761
Release: 2010-12-12
Genre: Health & Fitness
ISBN: 1420041789
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HERBAL MEDICINE FROM A WESTERN POINT OF VIEW Herbal remedies have become a major factor in American health care. Botanicals like Ginseng, Ma Huang, St. John's Wort, and Valerian are now household words throughout the world. Since many of these natural drugs are sold over the counter, often consumers mistakenly assume that they are completely

Pharmacodynamic Basis of Herbal Medicine

Pharmacodynamic Basis of Herbal Medicine
Author: Manuchair Ebadi
Publisher: CRC Press
Total Pages: 766
Release: 2006-09-06
Genre: Health & Fitness
ISBN: 1420006452
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Continuing the tradition of the acclaimed first edition, this book examines in detail the physiologic effects of food supplements, vitamins, and herbal remedies. Considering the site, mode, and mechanism of action, the author explains the desired and adverse effects and interactions of each herb, drug, and food, and either endorses or debunks popular conceptions with pure scientific data. Paying particular attention to diabetes, cardiovascular disease, and obesity, as well as incorporating current research on the role of chronic systemic inflammation and the cumulative effect of free radicals on the aging process, the author answers today's naturopathic questions. Deconstructing the interaction among herbal properties, physiology, and di

Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications

Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications
Author: Hai Yu Xu
Publisher: Frontiers Media SA
Total Pages: 1019
Release: 2023-09-19
Genre: Science
ISBN: 2832535518
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ntegrative Pharmacology can be used to determine the multi-pharmacological effects of traditional medicines such as traditional Chinese medicine (TCM), Kampo, Sa-sang, Ayurveda, etc.). Through qualitative and quantitative pharmacokinetic-pharmacodynamic (PK-PD) correlations among multi-constituents and multi-targets, integrating chemical profiling, ADME/PK processes, molecular network calculation and resulting experimental validation, the use of Integrative Pharmacology has become widespread. The data has provided a novel paradigm to evaluate the druggability of bioactive ingredients of herbs or formulae, to decipher the pharmacological mechanisms of drug action and to screen potentially new indications for approved drugs and previously unidentified adverse events. On this basis, Integrative Pharmacology may offer an effective way to test the potential scientific basis for traditional medicines and to assess what roles of traditional medicine can and cannot play in pharmaceuticals.

Evidence-Based Validation of Herbal Medicine

Evidence-Based Validation of Herbal Medicine
Author: Pulok K. Mukherjee
Publisher: Elsevier
Total Pages: 858
Release: 2022-07-12
Genre: Business & Economics
ISBN: 0323984568
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Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Herbal Products

Herbal Products
Author: Timothy S. Tracy
Publisher: Humana
Total Pages: 0
Release: 2010-11-19
Genre: Science
ISBN: 9781617374869
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Herbal Products: Toxicology and Clinical Pharmacology, Second Edition builds on the informative foundation laid by its predecessor. This fully revised and expanded second edition boasts more than 200 new references that document efficacy studies and adverse effects and four new chapters devoted to dietary products. Practitioners and researchers will find that this volume is a comprehensive resource for objective clinical information.

Natural Medicines

Natural Medicines
Author: Dilip K. Ghosh
Publisher: CRC Press
Total Pages: 604
Release: 2019
Genre:
ISBN: 9781138733060
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Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. Features * Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies * Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing * Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components * Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine * Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science. ility testing * Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components * Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine * Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.

Stockley's Herbal Medicines Interactions

Stockley's Herbal Medicines Interactions
Author: Elizabeth M. Williamson
Publisher:
Total Pages: 0
Release: 2009
Genre: Dietary supplements
ISBN: 9780853698654
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This is a professional level major reference work containing information, in A-Z format, on herb-drug, herb-supplement, herb -food and herb-laboratory test interactions; all of which is data referenced. Commercial herbal medicinal products are increasingly consumed on a regular basis by people in the developed world. Often such products are taken concurrently with conventional medicines, frequently without the knowledge of health care professionals. As more evidence has become available, there has been an increasing awareness of the potential and actual problems of interactions, often dangerous, between conventional medicines and herbal medicines. This proposed new major reference brings together available data on approximately 200 of the most commonly used herbal medicines in highly structured, rigorously scientific monographs. Although our texts on herbal medicines and drug interactions include the major well-known interactions, this text is able to treat the subject in considerably more detail.

The Pharmacology of Chinese Herbs, Second Edition

The Pharmacology of Chinese Herbs, Second Edition
Author: Kee C. Huang
Publisher: CRC Press
Total Pages: 538
Release: 1998-07-27
Genre: Science
ISBN: 9781420048261
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Records cataloging the healing powers of natural substances - plants, minerals, and animal byproducts - date back more than 4,000 years. There is no denying the effectiveness of traditional Chinese medicine, yet - until recently - the roots of this knowledge were largely lost in superstition and folklore. However, the use of herbs as an alternative medical treatment for many illnesses has increased steadily over the last decade, particularly since such herbs are categorized as "Natural Food Products" and are not yet subject to strict control by the FDA. Reports published in 1996 indicate that more than 10% of the US population has used herbal remedies. This book does not debate the value of Eastern or Western medicine but brings together Chinese herbal lore and Western scientific methods in a current, comprehensive treatise on the pharmacology of Chinese herbs. This second edition of The Pharmacology of Chinese Herbs presents the chemical composition, pharmacological action, toxicity, and therapeutic value of 473 herbs. The book: Classifies herbs according to their therapeutic value Informs how active ingredients in herbs may adversely interact with other herbs or drugs Evaluates which herbs have the potential for more investigation and possible use as drugs Describes the pharmacological action of each herb based on recent scientific study and describes each herb according to Chinese pharmacopoeia and folk medicine Provides a review of Chinese medical history Presents information on how to use modern chemical techniques for enhancing or modifying herbal ingredients into better agents with more strength and activity What's New in the Second Edition Discussions on: Herbs and their specific effects on the immune system Herbs and fertility/infertility Anti-cancer herbs Anti-HIV herbs Anti-malarial herbs Ginseng and ginsenosides Anti-Alzheimer herbs Herbs affecting the nervous system

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Author: H.Gerhard Vogel
Publisher: Springer Science & Business Media
Total Pages: 576
Release: 2010-12-15
Genre: Medical
ISBN: 3540898905
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Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

The Essential Guide to Herbal Safety

The Essential Guide to Herbal Safety
Author: Simon Y Mills
Publisher: Elsevier Health Sciences
Total Pages: 704
Release: 2004-12-23
Genre: Medical
ISBN: 0443071713
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Winner of American Botanical Council's 2005 James A. Duke Botanical Literature Award, the Essential Guide to Herbal Safety offers a balanced and objective perspective on the principles of herbal medicine safety as well as the complex challenges relating to self-prescribed or professionally prescribed herbal medications and supplements. With contributions from leading international practitioners and authorities, it contains comprehensive reviews, in monograph format, of the published safety data for 125 common herbs. You'll also find coverage of issues of quality, interactions, adverse reactions, toxicity, allergy, contact sensitivity, and idiosyncratic reactions. Provides the most current information on safety issues in herbal medicine. Presents authoritative and credible safety information from two experienced herbal practitioners. Combines theoretical chapters with 125 well-researched monographs, making it the most thorough and comprehensive text on the market for herbal safety in practice. Provides clear information using the most current evidence-based reviews, covering factors that influence herb safety, including the negative placebo effects (nocebo), various types of unpredictable effects, the basis for interactions between herbs and drugs, and quality issues. Uses an established grading system for assessing safety in pregnancy and lactation that is realistic and appropriate to herb use. Thoroughly critiques the dominant misinformation in the media and medical journals on herb safety issues. Contains 83 documented case studies on hepatoxicity and the effects in relation to kava. Kava safety is a hot topic. Includes two useful appendices detailing herbal references for pregnancy and lactation considerations.