Peptides And Protein Phosphorylation PDF Download
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Author | : B.E. Kemp |
Publisher | : CRC Press |
Total Pages | : 332 |
Release | : 2018-01-18 |
Genre | : Medical |
ISBN | : 1351083899 |
Download Peptides and Protein Phosphorylation Book in PDF, ePub and Kindle
This comprehensive volume focuses on the ways in which synthetic peptides have been exploited in order to expand our understanding of the molecular mechanisms involved in protein phosphorylation. It recognizes that virtually all physiological processes are regulated by protein phosphorylation. It discusses the use of synthetic peptides in studying the catalytic mechanism and regulation of protein kinases. It also includes the chemical synthesis of phosphorylated peptides and preparation of specific antisera. This incredible work has lead to the development of a new generation of peptide inhibitors with potencies of greater magnitude than those previously known. Everyone involved with biochemistry and molecular biology will find this one-of-a-kind resource fascinating and filled with useful information.
Author | : James Robert Feramisco |
Publisher | : |
Total Pages | : 324 |
Release | : 1979 |
Genre | : |
ISBN | : |
Download Phosphorylation of Synthetic Peptides by Cyclic AMP-dependent Protein Kinase Book in PDF, ePub and Kindle
Author | : J. Gordon |
Publisher | : S. Karger AG (Switzerland) |
Total Pages | : 256 |
Release | : 1980 |
Genre | : Medical |
ISBN | : |
Download Protein Phosphorylation and Bio-regulation Book in PDF, ePub and Kindle
Author | : Friedrich Marks |
Publisher | : John Wiley & Sons |
Total Pages | : 404 |
Release | : 2008-09-26 |
Genre | : Science |
ISBN | : 3527615024 |
Download Protein Phosphorylation Book in PDF, ePub and Kindle
Protein phosphorylation is a key mechanism in cellular signaling. This volume presents a state-of-the-art survey of one of the most rapidly developing fields of biochemical research. Written by leading experts, it presents the latest results for some of the most important cellular pathways. Color plates illustrate structural or functional relationships, numerous references provide links to the original literature.
Author | : Grahame Hardie |
Publisher | : OUP Oxford |
Total Pages | : 460 |
Release | : 1999-10-14 |
Genre | : Science |
ISBN | : 0191565903 |
Download Protein Phosphorylation Book in PDF, ePub and Kindle
Reversible phosphorylation is one of the major mechanisms of controlling protein activity in all eukaryotic cells. This new edition of Protein Phosphorylation: A Practical Approach provides a comprehensive description of current methods used to study protein phosphorylation and the kinases and phosphatases which catalyse it. It includes protocols for studying phosphorylation in intact cells; analysis of signal transduction pathways, kinase specificity, and kinase interactions; assay and purification of kinases and phosphatases; and identification of substrates. Also covered are cloning and expression protocols and advice on the crystallization of kinases and phosphatases. Protein Phosphorylation: A Practical Approach 2e will therefore be of great value to any researcher investigating aspects of reversible protein phosphrylation.
Author | : Ashraf Brik |
Publisher | : John Wiley & Sons |
Total Pages | : 626 |
Release | : 2021-06-08 |
Genre | : Science |
ISBN | : 3527346600 |
Download Total Chemical Synthesis of Proteins Book in PDF, ePub and Kindle
How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research. The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource: Contains valuable insights from the pioneers in the field of chemical protein synthesis Presents proven synthetic approaches for a range of protein families Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology.
Author | : D. Grahame Hardie |
Publisher | : IRL Press |
Total Pages | : 336 |
Release | : 1993 |
Genre | : Science |
ISBN | : |
Download Protein Phosphorylation Book in PDF, ePub and Kindle
Reversible phosphorylation is one of the major mechanisms by which protein activity is controlled in all eukaryotic cells. Networks of protein kinases and phosphatases, which catalyze phosphorylation and dephosphorylation respectively, are responsible for switching between different pathways of cell division, development, or differentiation in response to hormones or growth factors. This book provides a comprehensive description of current methods for studying protein phosphorylation and the protein kinases and phosphatases which catalyze it. It includes detailed protocols for studying phosphorylation in intact cells, approaches using enzyme inhibitors, purification of serine/threonine-specific protein kinases/phosphatases, analysis of kinase/phosphatase specificity, and cloning relevant cDNAs. Protein Phosphorylation: A Practical Approach will be of great value to all researchers in the fields of intracellular and intercellular signalling, including biochemists, molecular biologists and pharmacologists.
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Download Molecular Biology of The Cell Book in PDF, ePub and Kindle
Author | : L.M.G. Jr. Heilmeyer |
Publisher | : Springer Science & Business Media |
Total Pages | : 461 |
Release | : 2013-06-29 |
Genre | : Science |
ISBN | : 3642751423 |
Download Cellular Regulation by Protein Phosphorylation Book in PDF, ePub and Kindle
Proceedings of the NATO Advanced Study Institute on Cellular Regulation by Protein Phosphorylation held at Chateau La Londe les Maures (France), September 5-15, 1990
Author | : Shirish Shenolikar |
Publisher | : Academic Press |
Total Pages | : 464 |
Release | : 2012-02-28 |
Genre | : Medical |
ISBN | : 0123964563 |
Download Protein Phosphorylation in Health and Disease Book in PDF, ePub and Kindle
This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields. Contributions from leading authorities Informs and updates on all the latest developments in the field