Pancreatic Cancer Updates In Pathogenesis Diagnosis And Therapies PDF Download
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| Author | : Emad Hamdy Gad |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 130 |
| Release | : 2023-11-02 |
| Genre | : Medical |
| ISBN | : 1803559217 |
Download Pancreatic Cancer - Updates in Pathogenesis, Diagnosis and Therapies Book in PDF, ePub and Kindle
Pancreatic Cancer - Updates in Pathogenesis, Diagnosis and Therapies presents the most recent knowledge on pancreatic cancer, which is a deadly, challenging and catastrophic tumor with a high mortality rate. It is the seventh leading cause of cancer-related mortality worldwide. Pancreatic cancer can be diagnosed clinically, by laboratory measures, by imaging, and by pathological detection. Understanding tumor pathogenesis as well as tumor risk factors is necessary for successful treatment, as is early detection and multidisciplinary treatment. This book provides a comprehensive overview of pancreatic cancer in four sections. Chapters address such topics as prevention, screening, and detection; pathogenesis and risk factors; and pathology and management.
| Author | : Howard Reber |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 553 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461218101 |
Download Pancreatic Cancer Book in PDF, ePub and Kindle
A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances. i
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 392 |
| Release | : 2023-05-31 |
| Genre | : Medical |
| ISBN | : 0443133557 |
Download Pancreatic Cancer: Basic Mechanisms and Therapies Book in PDF, ePub and Kindle
Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research. Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States. Greater than 90% PCs are Pancreatic ductal adenocarcinomas (PDAC) which have a dismal estimated 5-year overall survival of only 11%. PDAC is predicted to become the second leading cause of mortality in the United States by 2030. In the clinic, the PDAC patients often present with incurable disease at the time of first diagnosis. This cancer is particularly lethal because of its propensity to spread quickly to distant organs including the lymphatic system. PDAC metastasis occurs shortly after tumor initiation and is caused by a complex interaction between autonomous tumor cells and cellular elements of the tumor microenvironment. Although PDAC remains a challenging disease to treat and a leading cause of cancer-related deaths, progress is being made in disease etiology and pathogenesis, and intensive research is focused on developing optimal treatment approaches for patients. Considering the continuous progress being made in understanding PDAC pathogenesis and designing new therapies, it was considered timely to develop an up-to-date thematic issue of Advances in Cancer Research (ACR) focused on PDAC. In this thematic issue, we have included ten review articles by experts that cover cancer disparities, PDAC pathobiology, the roles of the tumor microenvironment, tumor heterogeneity, PC stem cells, genetic and signaling events critical for PDAC pathogenesis, Immunotherapy and chemoresistance in PDAC, and different PDAC mouse models. This special issue highlights recent research progress in PDAC, which bridges the gap between basic and clinical research. The recent overview of Racial Disparities in Pancreatic Cancer Clinical Trials; Overview the evolution of in vivo models for PDAC Up-to-date discussion of diverse genetic and molecular signaling changes in PDAC; Role of tumor heterogeneity in therapy resistance in PDAC; Chemoresistance in PDAC and how to overcome this challenge; Current and emerging approaches and strategies for advancing targeted therapy and immunotherapy for PDAC New insights into the role of epithelial-to-mesenchymal transition, tumor microenvironment (TME) and interactions of TME with cancer stem cells in PDAC pathogenesis, progression and therapeutic resistance
| Author | : Ganji Purnachandra Nagaraju |
| Publisher | : Academic Press |
| Total Pages | : 420 |
| Release | : 2020-01-15 |
| Genre | : |
| ISBN | : 9780128194577 |
Download Theranostic Approach for Pancreatic Cancer Book in PDF, ePub and Kindle
Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. This book discusses several topics related to pancreatic cancer such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer Discusses treatment options available currently as well as prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment
| Author | : Andrew W. Bruce |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 363 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1447113985 |
Download Adenocarcinoma of the Prostate Book in PDF, ePub and Kindle
Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.
| Author | : Juan Enrique Dominguez-Munoz |
| Publisher | : John Wiley & Sons |
| Total Pages | : 752 |
| Release | : 2021-03-17 |
| Genre | : Medical |
| ISBN | : 111957014X |
Download Clinical Pancreatology for Practising Gastroenterologists and Surgeons Book in PDF, ePub and Kindle
Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.
| Author | : Ronnie Ann Rosenthal |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1364 |
| Release | : 2011-07-12 |
| Genre | : Medical |
| ISBN | : 1441969993 |
Download Principles and Practice of Geriatric Surgery Book in PDF, ePub and Kindle
"In the preface to this impressive and well-produced book, the editors state that their aim is not to describe a new surgical specialty, since most surgeons will soon need to be "geriatric surgeons," but to assemble a comprehensive account that will allow "all providers of healthcare to the elderly to understand the issues involved in choosing surgery as a treatment option for their patients." This is a useful book that deserves to do well. I hope that the editors and their publisher will have the stamina to make this the first of several editions, as it is clear that updated information about surgery in the elderly will be required to keep pace with this important field." NEJM Book Review
| Author | : Douglas B. Evans |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 413 |
| Release | : 2006-04-18 |
| Genre | : Medical |
| ISBN | : 0387216006 |
Download Pancreatic Cancer Book in PDF, ePub and Kindle
The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
| Author | : Hala Gali-Muhtasib |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 582 |
| Release | : 2011-11-21 |
| Genre | : Medical |
| ISBN | : 9533077034 |
Download Advances in Cancer Therapy Book in PDF, ePub and Kindle
The book "Advances in Cancer Therapy" is a new addition to the Intech collection of books and aims at providing scientists and clinicians with a comprehensive overview of the state of current knowledge and latest research findings in the area of cancer therapy. For this purpose research articles, clinical investigations and review papers that are thought to improve the readers' understanding of cancer therapy developments and/or to keep them up to date with the most recent advances in this field have been included in this book. With cancer being one of the most serious diseases of our times, I am confident that this book will meet the patients', physicians' and researchers' needs.
| Author | : Thomas M. Gress |
| Publisher | : IOS Press |
| Total Pages | : 124 |
| Release | : 2000 |
| Genre | : Pancreas |
| ISBN | : 9781586030407 |
Download Molecular Pathogenesis of Pancreatic Cancer Book in PDF, ePub and Kindle
This book was written to summarize the midterm meeting of the concerted action BMH4-CT98-3085 funded by the European Union in the context of the BIOMEDII programme. The objective of this concerted action (CA) is to generate a European network allowing to share expertise, technologies and resources to speed up the process of characterization of potential new disease genes in pancreatic cancer. The meeting in Barcelona in November 1999 was hosted by the group at the IMIM led by F.X. Real, and was scheduled to allow a midterm evaluation of the individual projects.
