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Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis

Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis
Author: E. Fernández
Publisher: Thieme
Total Pages: 582
Release: 2020-05-22
Genre: Science
ISBN: 3132429732

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The widespread use of organoboron compounds justifies the efforts devoted to their synthesis, as well as toward developing an understanding of their reactivity. The nature of the mono- or diboron species is of paramount importance in determining the reversible covalent binding properties of the boron atom with both nucleophiles and electrophiles. By wedding the rich chemical potential of organoboron compounds to the ubiquity of organic scaffolds, advanced borylation reactions have the potential to open unprecedented synthetic alternatives, and new knowledge in the field should encourage chemists to use organoboron compounds. In this volume, the main objective is to provide a collection of the most useful, practical, and reliable methods, reported mainly within the last decade, for boron activation and boron reactivity. The volume covers the main concepts of organoboron compounds and includes experimental procedures, enabling newcomers to the field the instant and reliable application of the new tools in synthesis. Rather than aiming for a comprehensive coverage, the most advanced solutions for challenging transformations are introduced. To this end, a team of pioneers and leaders in the field have been assembled who discuss both the practical and conceptual aspects of this rapidly growing field.


The Organic Chemistry of Boron

The Organic Chemistry of Boron
Author: William Gerrard
Publisher:
Total Pages: 328
Release: 1961
Genre: Science
ISBN:

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Boron Reagents in Synthesis

Boron Reagents in Synthesis
Author: Adiel Coca
Publisher: ACS Symposium
Total Pages: 544
Release: 2018-02-02
Genre: Science
ISBN: 9780841231832

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Boron compounds have been used extensively in organic synthesis for more than sixty years. Some of the best known reactions in synthesis, such as the Suzuki-Miyaura cross-coupling and the hydroboration reaction, involve boron compounds. Several natural products containing boron have been isolated in the last fifty years, including ionophoric macrodiolide antibiotics boromycin, borophycin, aplasmomycins A, B, and C, and tartrolons B, C, and E, as well as autoinducer-2. The study of compounds containing boronic acids for application in pharmaceuticals and materials science has grown tremendously over the last few decades. These include bortezomib, ixazomib, and tavaborole. Several more boron-based drugs are currently in clinical trials. Boron neutron capture therapy has the potential to provide a treatment for various cancers. In addition, materials bearing boronic acids are been studied as potential sensors for biological molecules, such as saccharides and glycoproteins that possess cis-1,2- or cis-1,3-diols.


Contemporary Boron Chemistry

Contemporary Boron Chemistry
Author: Matthew G Davidson
Publisher: Royal Society of Chemistry
Total Pages: 555
Release: 2007-10-31
Genre: Science
ISBN: 1847550649

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The continued and evolving significance of boron chemistry to the wider chemical community is demonstrated by the international and interdisciplinary nature of the research reported in this book. Contemporary Boron Chemistry encompasses inorganic and organic compounds as well as polymers, solid-state materials, medicinal aspects and theoretical studies. Covering many areas of chemistry with boron at its centre, topics include applications to polyolefin catalysis, medicine, materials and polymers; boron cluster chemistry, including carboranes and metal-containing clusters; organic and inorganic chemistry of species containing only 1 or 2 boron atoms; and theoretical studies of boron-containing compounds. New materials with novel optical and electronic properties are also discussed. Comprehensive and up to date, graduates and researchers in a wide range of fields, particularly those in organometallic and organic chemistry and materials science, will welcome this book.


Synthesis and Application of Organoboron Compounds

Synthesis and Application of Organoboron Compounds
Author: Elena Fernández
Publisher: Springer
Total Pages: 334
Release: 2015-03-04
Genre: Science
ISBN: 3319130544

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The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics in pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors.


Boron Fluoride and Its Compounds as Catalysts in Organic Chemistry

Boron Fluoride and Its Compounds as Catalysts in Organic Chemistry
Author: A. V. Topchiev
Publisher: Elsevier
Total Pages: 327
Release: 2013-10-22
Genre: Science
ISBN: 1483184366

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Boron Fluoride and Its Compounds as Catalysts in Organic Chemistry deals with the concerns associated with the utilization of boron fluoride as a catalyst. The title provides a comprehensive account of boron fluoride, such as its properties, compounds, and related methodologies. The coverage of the text includes the preparation and recovery of boron fluoride, along with the physical and chemical properties. The selection also covers various boron fluoride compounds and their respective reaction to various processes, such as alkylation, polymerization, and nitration. The book will be of great interest to students, researchers, and practitioners of organic chemistry.


Boron-Based Compounds

Boron-Based Compounds
Author: Evamarie Hey-Hawkins
Publisher: John Wiley & Sons
Total Pages: 490
Release: 2018-07-23
Genre: Science
ISBN: 1119275555

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Noted experts review the current status of boron-containing drugs and materials for molecular medical diagnostics Boron-Based Compounds offers a summary of the present status and promotes the further development of new boron-containing drugs and advanced materials, mostly boron clusters, for molecular medical diagnostics. The knowledge accumulated during the past decades on the chemistry and biology of bioorganic and organometallic boron compounds laid the foundation for the emergence of a new area of study and application of boron compounds as lipophilic pharmacophores and modulators of biologically active molecules.This important text brings together in one comprehensive volume contributions from renowned experts in the field of medicinal chemistry of boron compounds. The authors cover a range of the most relevant topics including boron compounds as modulators of the bioactivity of biomolecules, boron clusters as pharmacophores or for drug delivery, boron compounds for boron neutron capture therapy (BNCT) and for diagnostics, as well as in silico molecular modeling of boron- and carborane-containing compounds in drug design. Authoritative and accessible, Boron-Based Compounds: Contains contributions from a panel of internationally renowned experts in the field Offers a concise summary of the current status of boron-containing drugs and materials used for molecular diagnostics Highlights the range and capacity of boron-based compounds in medical applications Includes information on boron neutron capture therapy and diagnostics Designed for academic and industrial scientists, this important resource offers the cutting-edge information needed to understand the current state of boron-containing drugs and materials for molecular medical diagnostics.


Handbook Of Boron Science: With Applications In Organometallics, Catalysis, Materials And Medicine (In 4 Volumes)

Handbook Of Boron Science: With Applications In Organometallics, Catalysis, Materials And Medicine (In 4 Volumes)
Author: Narayan S Hosmane
Publisher: World Scientific
Total Pages: 1051
Release: 2018-08-07
Genre: Science
ISBN: 1786344432

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Boron science features in numerous fields including organic chemistry, organometallic chemistry and medicine. Boron is unique in all aspects of science and engineering and has made a significant impact in our daily lives through its use in fertilizers, germicides, fungicides, soaps, detergents, cancer drugs as well as many household glassware utensils, ceramics and cell phone windows. These volumes bring together an array of internationally renowned scientists to discuss the very latest developments in the application of boron in a broad range of disciplines. This multi-reference work describes the topic by appointing leading researchers to write on current developments in boron science, showcasing its importance to the four separate areas described in each volume: Organometallic Chemistry, Catalysis, Materials Chemistry and Medicine.Written to cover the full range of applications and innovations in boron science, this all-encompassing work offers us a one-stop reference compiled by world-leading researchers and practitioners of the subject, making it perfect for undergraduate and graduate students of chemistry, and researchers and practitioners interested in their professional development.


Fundamentals and Applications of Boron Chemistry

Fundamentals and Applications of Boron Chemistry
Author: Yinghuai Zhu
Publisher: Elsevier
Total Pages: 431
Release: 2022-03-17
Genre: Science
ISBN: 0128221267

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Fundamentals and Applications of Boron Chemistry highlights its impressive potential for current and future developments across a range of fields, providing foundational information on boron chemistry and systematically summarizing applications of boron in energy, medicinal chemistry, and materials chemistry. Beginning with an introduction to boron chemistry which outlines the boron element and its physical and chemical properties, this book goes on to discuss advances in boron coordination chemistry, before delving deeper into key fields of application. The latest developments in boron-based catalysts in organic reactions are reviewed, followed by novel emerging boron-containing materials and their potential applications in areas such as hydrogen storage, and boron materials with special optical activity. Finally, advance boron-based drugs and therapies are explored. This book fills the current market gap, systematically summarizing developments and applications of boron in energy, medicinal chemistry, and materials chemistry in a single, accessible volume. It is a valuable reference for chemists, students, and researchers in relative areas. Outlines the foundational principles and properties of boron chemistry Highlights developments in the application of boron chemistry across key areas, including catalysis, sustainable energy, material development, and pharmaceuticals Using active words to start them off Inspires researchers in developing future applications based on boron’s chemical characteristics and activity