Oecd Series On Testing And Assessment Guidance Document On Good In Vitro Method Practices Givimp PDF Download
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Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 206 |
Release | : 2018-12-10 |
Genre | : |
ISBN | : 9264304797 |
Download OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices (GIVIMP) Book in PDF, ePub and Kindle
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Author | : Organisation for Economic Co-operation and Development |
Publisher | : |
Total Pages | : 172 |
Release | : 2018 |
Genre | : |
ISBN | : 9789264311008 |
Download Guidance Document on Good In Vitro Method Practices (GIVIMP) Book in PDF, ePub and Kindle
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which data are generated must adhere to defined standards to ensure resulting data are rigorous and reproducible. Good In vitro Method Practices (GIVIMP) for the development and implementation of in vitro methods for regulatory use in human safety assessment aims to help reduce the uncertainties in cell and tissue-based in vitro method derived chemical safety predictions. GIVIMP provides guidance for test method developers and end users of resulting data on key elementes of in vitro methods. GIVIMP tackles ten important aspects related to in vitro work: (1) Roles and responsibilities, (2) Quality considerations, (3) Facilities (4) Apparatus, material and reagents, (5) Test systems, (6) Test and reference/control items, (7) Standard operating procedures (SOPs), (8) Performance of the method, (9) Reporting of results, (10) Storage and retention of records and materials.
Author | : Organisation for Economic Co-operation and Development |
Publisher | : |
Total Pages | : 172 |
Release | : 2018 |
Genre | : |
ISBN | : 9789264311015 |
Download Guidance Document on Good In Vitro Method Practices (GIVIMP) Book in PDF, ePub and Kindle
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which data are generated must adhere to defined standards to ensure resulting data are rigorous and reproducible. Good In vitro Method Practices (GIVIMP) for the development and implementation of in vitro methods for regulatory use in human safety assessment aims to help reduce the uncertainties in cell and tissue-based in vitro method derived chemical safety predictions. GIVIMP provides guidance for test method developers and end users of resulting data on key elementes of in vitro methods. GIVIMP tackles ten important aspects related to in vitro work: (1) Roles and responsibilities, (2) Quality considerations, (3) Facilities (4) Apparatus, material and reagents, (5) Test systems, (6) Test and reference/control items, (7) Standard operating procedures (SOPs), (8) Performance of the method, (9) Reporting of results, (10) Storage and retention of records and materials.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 17 |
Release | : 2017-04-13 |
Genre | : |
ISBN | : 9264274731 |
Download OECD Series on Testing and Assessment Guidance Document for Describing Non-Guideline In Vitro Test Methods Book in PDF, ePub and Kindle
The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the quality of data produced, irrespective of whether ...
Author | : |
Publisher | : |
Total Pages | : |
Release | : |
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Download Guidance Document on Good In Vitro Method Practices (GIVIMP). Book in PDF, ePub and Kindle
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 23 |
Release | : 2017-04-13 |
Genre | : |
ISBN | : 9264274820 |
Download OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment Book in PDF, ePub and Kindle
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to testing and assessment that can be used as one of ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 31 |
Release | : 2004-11-01 |
Genre | : |
ISBN | : 9264078797 |
Download OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Conduct of Skin Absorption Studies Book in PDF, ePub and Kindle
This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 28 |
Release | : 2002-05-10 |
Genre | : |
ISBN | : 9264077928 |
Download OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Development of OECD Guidelines for Testing of Chemicals Book in PDF, ePub and Kindle
This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 40 |
Release | : 2002-05-10 |
Genre | : |
ISBN | : 9264078371 |
Download OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Human Endpoints for Experimental Animals Used in Safety Evaluation Book in PDF, ePub and Kindle
The purpose of this Guidance Document is to apply the principles of the Three Rs to the use of animals in regulatory toxicity tests. The OECD encourages the humane use of animals in regulatory toxicity and safety evaluation studies and fully endorses the principles of the 3Rs, Replacement, Reduction, Refinement.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 54 |
Release | : 2002-05-10 |
Genre | : |
ISBN | : 9264078401 |
Download OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures Book in PDF, ePub and Kindle
This document provides guidance for the testing of substances, and mixtures, classed as “difficult to test” for the purposes of determining their aquatic toxicity. Whilst the guidance given is targeted towards tests described by the OECD Guidelines identified it may also be relevant to other tests. The guidance relates to the practical aspects of carrying out valid tests with “difficult” test substances and mixtures and presenting the results. The guidance is considered to reflect good practice but it is important to recognise that some test substances and mixtures will present specific scientific and technical issues that may fall outside its scope. This document is divided into five substantive sections covering guidance for carrying out a preliminary assessment of test substance stability; general considerations on selection of exposure regimes; development of media preparation and exposure systems; sampling of test media for analysis, and calculating and reporting test results.