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| Author | : Uday Kishore |
| Publisher | : Frontiers Media SA |
| Total Pages | : 205 |
| Release | : 2020-05-05 |
| Genre | : |
| ISBN | : 2889636801 |
| Author | : Taruna Madan |
| Publisher | : Frontiers Media SA |
| Total Pages | : 181 |
| Release | : 2023-04-10 |
| Genre | : Medical |
| ISBN | : 2832520200 |
| Author | : Manzoor M. Khan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 275 |
| Release | : 2008-12-19 |
| Genre | : Medical |
| ISBN | : 0387779760 |
During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.
| Author | : Mitchell D. Cohen |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 492 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461545358 |
Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract. It will be useful to investigators in the field of pulmonary toxicology and immunotoxicology, and to those involved in administration and regulation of matters related to inhaled materials. It can also serve as a textbook for a course in pulmonary immunotoxicology at graduate or advanced undergraduate level. Pulmonary Immunotoxicology comprises four sections. The first provides basic background concepts essential for understanding pulmonary immunotoxicology, including discussions of the normal structure and function of the respiratory system, its basic immunology, and the manner by which inhaled particles and gases are removed from the air and deposited upon respiratory tract surfaces. The second section provides an overview of the major types of pathological consequences which can arise from immunomodulation within the respiratory tract, including hypersensitivity and asthma, inflammation and fibrosis, as well as immunosuppression and autoimmunity. The third section, which comprises the largest portion of the book, deals specifically with major classes of airborne agents that are known to alter the immune function of the respiratory tract. These are arranged into major classes: organic agents, metals, gases, particles, biologics, and complex mixtures. The fourth and final section of the book explores the area of risk assessment, including discussions of the basic concepts of risk assessment as they apply specifically to immunotoxicologic effects upon the lungs, and the use of biomarkers as indices of potential pulmonary immunotoxic responses to inhaled materials.
| Author | : Henk G. Merkus |
| Publisher | : Springer |
| Total Pages | : 455 |
| Release | : 2018-09-06 |
| Genre | : Technology & Engineering |
| ISBN | : 3319941747 |
This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.
| Author | : Blaine Pfeifer |
| Publisher | : Humana |
| Total Pages | : 591 |
| Release | : 2020-11-19 |
| Genre | : Science |
| ISBN | : 9781071607947 |
This volume discusses the vaccine development process and the role delivery concepts contribute to a global goal of effective health outcomes. The chapters in this book cover a wide range of topics such as antigen discovery methods; genetic and protein antigen preparation; preparation of viral vaccines as VLPs; viral and non-viral gene delivery; needle-less or non-invasive delivery technology; vaccine storage; and vaccine administration and assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step, readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vaccine Delivery Technology: Methods and Protocols is a valuable resource for both novice and expert researchers, in and outside the field, who would like to gain insight into the impactful field of vaccines. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
| Author | : Paul Ellis Marik |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 696 |
| Release | : 2010-06-14 |
| Genre | : Medical |
| ISBN | : 1441959238 |
This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding numerous references.
| Author | : Busi Siddhardha |
| Publisher | : Springer Nature |
| Total Pages | : 685 |
| Release | : 2020-03-28 |
| Genre | : Science |
| ISBN | : 9811516952 |
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
| Author | : Mark D. Kilby |
| Publisher | : Cambridge University Press |
| Total Pages | : 471 |
| Release | : 2013 |
| Genre | : Medical |
| ISBN | : 1107012139 |
Covers the latest insights any fetal specialist needs and provides essential knowledge for professionals caring for women with high-risk pregnancies.
| Author | : Arnold von Eckardstein |
| Publisher | : Springer Nature |
| Total Pages | : 537 |
| Release | : 2022 |
| Genre | : Atherosclerosis |
| ISBN | : 3030860760 |
This open access book is supported by the European Atherosclerosis Society Association (EAS). This follow-up edition of the well-received Handbook volume 'Atherosclerosis: Diet and Drugs' reflects the state-of-the-art and most recent developments in atherosclerosis research. Outstanding international experts give a comprehensive overview of the field covering topics, such as improving the treatment focusing on established targets, novel drug developments addressing pre-defined targets, hypothesis-based and hypothesis-free approaches to unravel novel targets.
