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Modern Strategies for Heterocycle Synthesis

Modern Strategies for Heterocycle Synthesis
Author: Gianfranco Favi
Publisher: MDPI
Total Pages: 372
Release: 2021-03-17
Genre: Medical
ISBN: 3036503404

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Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.


More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set
Author: Ana Maria Faisca Phillips
Publisher: John Wiley & Sons
Total Pages: 759
Release: 2022-04-11
Genre: Science
ISBN: 1119757142

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More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.


Novel Strategies in the Chemistry of N-Amino Heterocycles

Novel Strategies in the Chemistry of N-Amino Heterocycles
Author: Davit Jishkariani
Publisher:
Total Pages: 99
Release: 2012
Genre:
ISBN:

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The theme of this work is to develop n ove l methodologies for the synthesis of various organic compounds . Chapter 1 provides a general introduction to the subsequent chapters and the methods used throughout the thesis. Chapter 2 describes the utility of N - acylbenzotriazoles for the synthesis of ib uprofen and naproxen prodrugs. Chapters 3, 4, and 5 examine the chemistry of N - amino heterocycles. Chapter 3 describes the synthesis of 1 - aminobenzimidazoles and their transformations towards zwitterionic betaines and spirocyclic dithiohydantoins mediated by N - heterocyclic carbenes (NHC). The reversible thermal equilibrium of these spirocyclic dithiohydantoins is presented in Chapter 4, where the equilibrium is studied by various analytical methods. Chapter 5 focuses on the regioselective synthesis of p yra zolo[5,1 - c] - 1,2,4 - triazoles. Synthesis of pyrazolo[5,1 - c] - 1,2,4 - triazoles w as achieved via one - pot Cu (I) catalyzed reactions between 1,2,4 - triazolium N - imides and terminal alkynes . T he scope of alkyne substrates together with the effect of variations in t he 1 - alkyl substituent and the nature of the leaving group w as examined. 16 Conclusions, summary of the achievements and final remarks are presented in Chapter 6.


Strategies for the Synthesis of Heterocycles and Their Applications

Strategies for the Synthesis of Heterocycles and Their Applications
Author: Premlata Kumari
Publisher: BoD – Books on Demand
Total Pages: 256
Release: 2023-07-19
Genre: Science
ISBN: 1837682410

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Heterocycles are present in the molecular architecture of a wide variety of natural products and compounds with significant biological potency. The numerous heterocycles are employed as significant intermediates in the fields of synthetic organic chemistry, pharmaceuticals, and organic synthesis. This book summarizes the synthesis of different heterocycles using various synthetic methods, including green methods, and applications of heterocycles in various fields.


More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set
Author: Ana Maria Faisca Phillips
Publisher: John Wiley & Sons
Total Pages: 759
Release: 2022-04-04
Genre: Science
ISBN: 1119757126

Download More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set Book in PDF, ePub and Kindle

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.