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Normally, This Would be Cause for Concern

Normally, This Would be Cause for Concern
Author: Danielle Fishel
Publisher: Simon and Schuster
Total Pages: 224
Release: 2014-09-09
Genre: Biography & Autobiography
ISBN: 147676025X

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A warm and witty memoir by Danielle Fishel—“a talented actor who has always led with her heart” (Ben Savage)—the beloved star of the ’90s sitcom Boy Meets World and its hilarious new spin-off, Girl Meets World. Best known for playing Topanga Lawrence on Boy Meets World, Danielle Fishel was the quintessential girl-next-door for seven years as she joined 10 million viewers in their living rooms every Friday from 1993 to 2000. The real Danielle is just as entertaining and down-to-earth as the character she portrayed on her hit show. But life even for a successful actress can be messy, from disastrous auditions to dating mishaps and awkward red carpet moments. Normally, This Would Be Cause for Concern is a fun romp through Danielle’s own imperfections. It’s a book for anyone who, like Danielle, has ever tripped and fallen down a flight of stairs in a room full of people, had a romantic moment with a significant other ruined by gas, or taken a Halloween photo without realizing there was a huge chunk of strawberry in their teeth. Here is the real, imperfect Danielle, who knows that a good sense of humor and a positive attitude makes life so much more enjoyable. Even when you’ve just face-planted in front of Ben Affleck.


Targeted Drug Strategies for Cancer and Inflammation

Targeted Drug Strategies for Cancer and Inflammation
Author: Ann L. Jackman
Publisher: Springer Science & Business Media
Total Pages: 262
Release: 2011-05-05
Genre: Medical
ISBN: 1441984178

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Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made within the last decade include (i) the approval of pemetrexed for the treatment of lung cancer and mesothelioma, and (ii) the demonstration that cell membrane-anchored folate receptors (FR) are exploitable for cancer and inflammatory disease management. FRs are not widely distributed in normal tissues, except on some luminal surfaces; however, they are accessible to systemically administered agents when expressed on many cancers as well as on activated macrophages involved in various inflammatory diseases. High affinity folate-radioisotope conjugates have been developed for imaging pathogenic FR-positive diseases, including cancer. Since the FR transports folates via a low capacity but high affinity endocytic pathway, a variety of FR-targeted antifolate drugs and folate conjugates bearing a wide range of payloads (including cytotoxic drugs) are currently being developed which exploit this property. The FR is also being utilized in immunotherapy approaches for the treatment of overexpressing cancers.


How to Get Off Psychiatric Drugs Safely

How to Get Off Psychiatric Drugs Safely
Author: Jim Harper
Publisher: Off Psychiatric Drugs Safely
Total Pages: 169
Release: 2007
Genre: Psychotropic drugs
ISBN: 0615180590

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Wiley CPA Examination Review, Problems and Solutions

Wiley CPA Examination Review, Problems and Solutions
Author: Patrick R. Delaney
Publisher: John Wiley & Sons
Total Pages: 1480
Release: 2012-05-23
Genre: Study Aids
ISBN: 1118287185

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The #1 CPA exam review self-study leader The CPA exam review self-study program more CPA candidates turn to take the test and pass it, Wiley CPA Exam Review 39th Edition contains more than 4,200 multiple-choice questions and includes complete information on the Task Based Simulations. Published annually, this comprehensive two-volume paperback set provides all the information candidates need to master in order to pass the new Uniform CPA Examination format. Features multiple-choice questions, new AICPA Task Based Simulations, and written communication questions, all based on the new CBT-e format Covers all requirements and divides the exam into 47 self-contained modules for flexible study Offers nearly three times as many examples as other CPA exam study guides With timely and up-to-the-minute coverage, Wiley CPA Exam Review 39th Edition covers all requirements for the CPA Exam, giving the candidate maximum flexibility in planning their course of study—and success.


The Cat Encyclopedia

The Cat Encyclopedia
Author: DK
Publisher: Penguin
Total Pages: 322
Release: 2014-07-01
Genre: Pets
ISBN: 1465434437

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DK's new cat book, The Cat Encyclopedia, includes an introduction to feline anatomy, expert advice on kitten and cat care, and a celebration of cats in art and culture. Stunning photos of cat breeds from around the world form the core of the book, with information on the characteristics, origins, and behavior of each cat, as well as famous patrons of the breed. The Cat Encyclopedia is a celebration of all things feline, with a fully illustrated catalog of cat breeds including those recognized by TICA, CFA, GCCF and FIFe. The Cat Encyclopedia contains everything you need to know about cats in one easy-reference volume.


Melissa Explains It All

Melissa Explains It All
Author: Melissa Joan Hart
Publisher: Macmillan + ORM
Total Pages: 323
Release: 2013-10-29
Genre: Biography & Autobiography
ISBN: 1250032849

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Melissa Joan Hart explained it all-from dating to bullies-in her groundbreaking role as Clarissa Darling on Clarissa Explains It All. She cast a spell on millions more viewers as Sabrina, the Teenage Witch. Now, in Melissa Explains It All, Melissa tells the frank and funny behind-the-scenes stories from her extraordinary past and her refreshingly normal present. Melissa has been entertaining audiences most of her life; when there were no girls named Melissa on her favorite show, the forceful four year old decided she'd get on television her way. From that moment on, Melissa has shown a singular determination and focus-whether it's for booking three national commercials so her dad would build her a tree house or for nailing the audition for Clarissa. From her first commercial to her current starring role in ABC Family's hit Melissa andJoey, Hart never let fame go to her head. She always had one foot in Hollywood and one foot in reality-and still does. Melissa makes us laugh along with her as she talks about: --guest appearances in shows like Saturday Night Live and The Equalizer --auditioning for Punky Brewster and Clarissa --her early Broadway days --wacky parties she's thrown and attended -- the actors who influenced her and whom she befriended, worked with and competed against --her experiences both on and off-set-with Sabrina's Salem the Cat and Elvis the Alligator on Clarissa --how she met the love of her life at the Kentucky Derby Melissa Joan Hart explains all that she's learned along the way-what's kept her grounded, normal and working when others have not been so fortunate-and that she's the approachable, hilarious girl-next-door her fans have always thought she'd be.


Wiley CPA Examination Review, Problems and Solutions

Wiley CPA Examination Review, Problems and Solutions
Author: O. Ray Whittington
Publisher: John Wiley & Sons
Total Pages: 1554
Release: 2013-06-21
Genre: Study Aids
ISBN: 1118760042

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The #1 CPA exam review self-study leader The CPA exam review self-study program more CPA candidates trust to prepare for the CPA exam and pass it, Wiley CPA Exam Review 40th Edition contains more than 4,200 multiple-choice questions and includes complete information on the Task Based Simulations. Published annually, this comprehensive two-volume paperback set provides all the information candidates need in order to pass the Uniform CPA Examination format. Features multiple-choice questions, AICPA Task Based Simulations, and written communication questions, all based on the CBT-e format Covers all requirements and divides the exam into 47 self-contained modules for flexible study Offers nearly three times as many examples as other CPA exam study guides Other titles by Whittington: Wiley CPA Exam Review 2013 With timely and up-to-the-minute coverage, Wiley CPA Exam Review 40th Edition covers all requirements for the CPA Exam, giving the candidate maximum flexibility in planning their course of study, and success.


Blemished Harvest When the American Dream Goes Wrong

Blemished Harvest When the American Dream Goes Wrong
Author: Dan Weatherington
Publisher: Dan Weatherington
Total Pages: 198
Release: 2007-10-31
Genre:
ISBN: 143484174X

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Climbing the corporate ladder is supposed to assure the American Dream, but every once in a while a rung on the ladder breaks.