Neurodegeneration And Neuroprotection In Multiple Sclerosis PDF Download
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| Author | : P. Riederer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 442 |
| Release | : 2013-03-14 |
| Genre | : Medical |
| ISBN | : 3709163013 |
Download Advances in Research on Neurodegeneration Book in PDF, ePub and Kindle
The 8th International Winter Conference on Neurodegeneration from Febru ary 9 to 13, 2000 took place in Tegernsee, Bavaria, Germany. The interest shown in this symposium, which was carried by invited speakers only, was striking. 28 lectures in 5 sessions dealt with themes on basic science and therapy strategies for neurodegenerative illness. This time especially basic mechanism of cell death and resulting causal treatment possibilities were centre themes of the lectures and lively discussions. In accordance with tradi tion 5 lectures on Multiple Sclerosis finished the convention. 60 scientists from 13 countries discussed current questions to these themes. The Symposium started with a lecture on the history of the develop ment of modern-L-DOPA-therapy. Lectures on cell death of dopaminergic nerve cells, new valuation regarding assembly, built up and function of neuromelanin of Substantia nigra and with this, the question of the physio logic and pathobiochemical role of dopamine and neuromelanin built the first block of themes which consequently extended to molecular and genetic aspects of cell death. Highlights of the symposium were neuroprotective and neuroregenerative future therapy strategies together with discussions on the difficulties of clinical neuroprotection. Developmental biological aspects on nerve cells, reorganisation and neurodegeneration showed a stimulating point of view of momentary and future development possibilities of new and more causal forms of therapy of neurodegenerative illness.
| Author | : Ian D. Duncan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 296 |
| Release | : 2012-08-31 |
| Genre | : Medical |
| ISBN | : 1461422183 |
Download Myelin Repair and Neuroprotection in Multiple Sclerosis Book in PDF, ePub and Kindle
Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier. Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.
| Author | : M. Filippi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 233 |
| Release | : 2008-02-01 |
| Genre | : Medical |
| ISBN | : 8847003911 |
Download Neurodegeneration in Multiple Sclerosis Book in PDF, ePub and Kindle
Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it is an indispensable tool for all those working in this field. The context in which this book exists is that there is an increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information.
| Author | : Aaron E. Miller |
| Publisher | : |
| Total Pages | : 25 |
| Release | : 2005 |
| Genre | : |
| ISBN | : |
Download Neurodegeneration and Neuroprotection in Multiple Sclerosis Book in PDF, ePub and Kindle
| Author | : Alireza Minagar |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2015-12-02 |
| Genre | : Medical |
| ISBN | : 9780128007631 |
Download Multiple Sclerosis Book in PDF, ePub and Kindle
Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS. The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS. It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study.
| Author | : Raymond Chuen-Chung Chang |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 104 |
| Release | : 2019-08-28 |
| Genre | : Medical |
| ISBN | : 1789847362 |
Download Neuroprotection Book in PDF, ePub and Kindle
Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In this book, there are chapters discussing imidazoline ligands and opioid ligands in Alzheimer's disease, the beneficial effects of adenosine A2A receptor antagonist, adrenergic receptor agonists and antagonists modulating microglial responses, and different approaches to achieve neuroprotection against aging-associated macular degeneration. This book will give insights to scientists in the field to stimulate their research, medical professionals to review their clinical practices, and others who would like to learn more about different neuroprotective approaches.
| Author | : Mathias Bähr |
| Publisher | : John Wiley & Sons |
| Total Pages | : 390 |
| Release | : 2006-03-06 |
| Genre | : Medical |
| ISBN | : 3527604316 |
Download Neuroprotection Book in PDF, ePub and Kindle
In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
| Author | : Stephen Waxman |
| Publisher | : Elsevier |
| Total Pages | : 495 |
| Release | : 2005-05-27 |
| Genre | : Medical |
| ISBN | : 0080489419 |
Download Multiple Sclerosis As A Neuronal Disease Book in PDF, ePub and Kindle
This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities. * Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis* Places MS in a new and important perspective that promises to open up new therapeutic avenues* Superbly illustrated and referenced
| Author | : Werner Poewe |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 170 |
| Release | : 1999-04-15 |
| Genre | : Medical |
| ISBN | : 9783211832622 |
Download Advances in Research on Neurodegeneration Book in PDF, ePub and Kindle
The book contains original articles and reviews presented at the 6th International Winter Conference on Neurodegeneration, held from November 20a "23, 1997 in KitzbA1/4hel/Austria. The aim of this conference was to present and discuss recent data on the interface between neuroimmunology and neurodegeneration, in particular susceptibility to autoimmune and neurodegenerative processes, neuroprotection and restorative treatment strategies. These issues were discussed in the light of recent developments in multiple sclerosis, Parkinsona (TM)s disease, amyotrophic lateral sclerosis, Huntingtona (TM)s disease and multisystem atrophy. The articles highlight topics, which are particularly interesting for the clinician and the neuroscientist. Some of the neuroprotective strategies have already been developed or are at present clinically investigated. The neuroprotective role of deep brain stimulation, antiglutamatergic therapy and apomorphine will be verified in clinical studies in the near future. This is also the case for future therapeutic approaches to restoration of the damaged nervous system, such as somatic gene therapy, implantation of genetically modified cell-lines and medically controlled and directed development of embryonic cells. The conference highlighted the role of the glia, which seems to play a key role, both in traditionally as neuroimmunological and neurodegenerative disorders classified diseases, as indicated above. The topics discussed in the book are significant for recent developments in clinical neurology and neuroscience, as shown in the current literature and at international congresses.
| Author | : Hari Shanker Sharma |
| Publisher | : Academic Press |
| Total Pages | : 420 |
| Release | : 2012-07-10 |
| Genre | : Medical |
| ISBN | : 0123869862 |
Download New Perspectives of Central Nervous System Injury and Neuroprotection Book in PDF, ePub and Kindle
Annotation Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Reviews written by experts in such a way thatprovides basic knowledge for beginners and advanced information for researchers and experts. New aspects of Neurodegenerative diseasessuch as;Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis are presented with thelatest therapeutic measures. Exacerbation of brain pathology in hypertension or diabetes is discussed for the first time.
