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Neurochemical Aspects of Alzheimer's Disease

Neurochemical Aspects of Alzheimer's Disease
Author: Akhlaq A. Farooqui
Publisher: Academic Press
Total Pages: 416
Release: 2017-05-25
Genre: Psychology
ISBN: 0128099380

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Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders. Provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies for Alzheimer's disease Written for researchers, clinicians, and advanced graduate students in neurology, neuroscience, neurochemistry, and neuropharmacology Acts as the first book to provide a comprehensive description of the signal transduction processes associated with pathogenesis of Alzheimer's disease


A Multidisciplinary Approach to Capability in Age and Ageing

A Multidisciplinary Approach to Capability in Age and Ageing
Author: Hanna Falk Erhag
Publisher: Springer Nature
Total Pages: 254
Release: 2022-01-10
Genre: Social Science
ISBN: 3030780635

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This open access book provides insight on how to interpret capability in ageing – one’s individual ability to perform actions in order to reach goals one has reason to value – from a multidisciplinary approach. With for the first time in history there being more people in the world aged 60 years and over than there are children below the age of 5, the book describes this demographic trends as well as the large global challenges and important societal implications this will have such as a worldwide increase in the number of persons affected with dementia, and in the ratio of retired persons to those still in the labor market. Through contributions from many different research areas, it discussed how capability depends on interactions between the individual (e.g. health, genetics, personality, intellectual capacity), environment (e.g. family, friends, home, work place), and society (e.g. political decisions, ageism, historical period). The final chapter summarizes the differences and similarities in these contributions. As such this book provides an interesting read for students, teachers and researchers at different levels and from different fields interested in capability and multidisciplinary research.


Alzheimer's Disease

Alzheimer's Disease
Author: Thimmaiah Govindaraju
Publisher: Royal Society of Chemistry
Total Pages: 695
Release: 2022-01-12
Genre: Medical
ISBN: 1839162309

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Handbook on Alzheimer's disease from aetiology and neurochemistry to diagnostic and therapeutic approaches. Intended to provide an introduction to all aspects of the disease.


Animal Models of Dementia

Animal Models of Dementia
Author: Joseph T. Coyle
Publisher:
Total Pages: 344
Release: 1987
Genre: Medical
ISBN:

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The Neurobiology of Alzheimer's Disease

The Neurobiology of Alzheimer's Disease
Author: Study Group on the Pharmacology of Memory Disorders Associated with Aging. Meeting
Publisher:
Total Pages: 460
Release: 1996
Genre: Medical
ISBN:

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The overall goal of the International Study Group on the Pharmacology of Memory Disorders Associated with Ageing is to point out discoveries that shed light on the potential causes of Alzheimer's disease, its pathogenesis, and the biological mechanisms that could underlie its cure. This eighth meeting in the series, aims to stimulate research in dementia and increase the transfer of information from the basic sciences to physicians and the pharmaceutical industry."


Neurobiology of Alzheimer's Disease

Neurobiology of Alzheimer's Disease
Author: David Dawbarn
Publisher: Oxford University Press, USA
Total Pages: 444
Release: 2001
Genre: Medical
ISBN:

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This revised edition of a book first published in 1995, presents an accessible overview of Alzheimer's disease, with an emphasis on research into the molecular mechanisms of neuronal degeneration. International experts have provided in-depth reviews of their areas of expertise, including coverage of the key molecules known to be involved, such as Ab, tau, apolipoprotein E and the presenilins. Other areas covered include neuropathology, genetics, neurochemical pathology, inflammation, diagnosis, models of the disease and opportunities for treatment, employing both existing and emerging drug therapies. The book will provide a readable introduction for those new to the subject, as well as covering a wide range of specialist topics for more experienced researchers and those interested in the overlap with other related specialist areas. Also included are appendices detailing gene and protein information on APP, tau, the presenilins, apolipoprotein E and the newly cloned therapeutic target, BACE.