Multi Dimensional Liquid Chromatography PDF Download
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Author | : Dwight R. Stoll |
Publisher | : CRC Press |
Total Pages | : 401 |
Release | : 2022-12-30 |
Genre | : Science |
ISBN | : 1000817334 |
Download Multi-Dimensional Liquid Chromatography Book in PDF, ePub and Kindle
Two-dimensional liquid chromatography (2D-LC) is finding increasingly wide application principally due to the analysis of mixtures of moderate to high complexity. Many industries are developing increasingly complex products that are challenging the separation capabilities of state-of-the-art 1D-LC and need new analytical methodologies with substantially more resolving power, and 2D-LC meets that need. This text, organized by two leaders in the field, establishes a sound fundamental basis for the principles of the technique, followed by a discussion of important practical considerations. The book begins with an introduction to multi-dimensional separations and a discussion of the history and development of the technique over the past 40 years, followed by several chapters that provide a theoretical basis for development of 2D-LC methods, including foundational concepts regarding separation complementarity, under-sampling, and dynamics of liquid chromatography separations. Instrumentation for 2D-LC is discussed extensively, including practical aspects such as interface selection and setup. Building on this foundation, two separate chapters are focused on method development for non-comprehensive and comprehensive separations, followed by a chapter dedicated to data analysis. Finally, applications of 2D-LC in several fields ranging from pharmaceutical analysis to polymer science are summarized. The book is an important resource for both students and practitioners who are already using 2D-LC or are interested in getting started in the field. Key Features: Demonstrates the conditions under which a 2D-LC method should be considered as an alternative to a 1D-LC method. Establishes a sound fundamental basis of the principles of the technique, followed by guidelines for method optimization. Provides a single source for technical knowledge advances and practical guidance described in recent literature. Assists with the initial decision to develop a 2D-LC method. Guides the reader in developing a high-quality method that meets the needs of their application.
Author | : Luigi Mondello |
Publisher | : John Wiley & Sons |
Total Pages | : 464 |
Release | : 2002-02-15 |
Genre | : Science |
ISBN | : 9780471988694 |
Download Multidimensional Chromatography Book in PDF, ePub and Kindle
Mehrdimensionale Chromatographie im analytischen Labor: Dieses Buch bespricht erstmals alle gängigen Verfahren sowie Anwendungen auf verschiedensten Gebieten, von der Pharmazie, Biologie und Chemie bis hin zur Umwelttechnik und erdölverarbeitender Industrie. Die Autoren sind selbst aktiv in der einschlägigen Forschung tätig.
Author | : Ayenew Ashenef |
Publisher | : |
Total Pages | : 0 |
Release | : 2019 |
Genre | : Electronic books |
ISBN | : |
Download Perspective Chapter Book in PDF, ePub and Kindle
Many complex mixtures usually constitute hundreds or even thousands of individual components of interest. Such mixtures are much too complicated to be separated for analytical duties in a reasonable period of time using only a single-dimensional chromatographic method. However, if a complex mixture is separated by an initial dimension using multi-dimensional liquid chromatography, a simpler portion of that separation is collected and goes to the second dimension. Each of these fractions will be analyzed separately, allowing exceedingly complex mixtures to be resolved in a short period of time. This chapter explains the fundamental principles, theoretical discussions as well as various applications with typical examples of multi-dimensional liquid chromatography in different fields.
Author | : |
Publisher | : |
Total Pages | : |
Release | : 2008 |
Genre | : |
ISBN | : |
Download Applications of Multi-Dimensional Liquid Chromatography in Biomedical, Pharmaceutical and Biopharmaceutical Analysis Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 257 |
Release | : 2015 |
Genre | : |
ISBN | : 9789462951563 |
Download Development of Separation Systems for Multi-dimensional Liquid Chromatography Book in PDF, ePub and Kindle
Author | : Harald Pasch |
Publisher | : Springer Science & Business Media |
Total Pages | : 291 |
Release | : 2013-06-12 |
Genre | : Technology & Engineering |
ISBN | : 3642360807 |
Download Multidimensional HPLC of Polymers Book in PDF, ePub and Kindle
This book presents the principle ideas of combining different analytical techniques in multi-dimensional analysis schemes. It reviews the basic principles and instrumentation of multi-dimensional chromatography and the hyphenation of liquid chromatography with selective spectroscopic detectors and presents experimental protocols for the analysis of complex polymers. It is the consequent continuation of "HPLC of Polymers" from 1999 by the same authors. Like its 'predecessor', this book discusses the theoretical background, equipment, experimental procedures and applications for each separation technique, but in contrast treats multi-dimensional and coupled techniques. "Multidimensional HPLC of Polymers" intends to review the state of the art in polymer chromatography and to summarize the developments in the field during the last 15 years. With its tutorial and laboratory manual style it is written for beginners as well as for experienced chromatographers, and will enable its readers (polymer chemists, physicists and material scientists, as well as students of polymer and analytical sciences) to optimize the experimental conditions for their specific separation problems.
Author | : Steven A. Cohen |
Publisher | : John Wiley & Sons |
Total Pages | : 490 |
Release | : 2008-05-09 |
Genre | : Science |
ISBN | : 0470276258 |
Download Multidimensional Liquid Chromatography Book in PDF, ePub and Kindle
Multidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this reference includes chapters contributed by leading experts or teams of experts.
Author | : Oliver Jones |
Publisher | : Springer Nature |
Total Pages | : 86 |
Release | : 2020-07-13 |
Genre | : Science |
ISBN | : 9811561907 |
Download Two-Dimensional Liquid Chromatography Book in PDF, ePub and Kindle
This book addresses the growing interest in the field of two-dimensional liquid chromatography (2DLC), a powerful approach to increasing resolution, available peak capacity, and selectivity in analytical chromatography. 2DLC is suitable for many applications, including in the pharmaceutical and polymer industries and the omic sciences (metabolomics, lipidomics and proteomics). Thanks to recent advances in technology and software the instrumentation needed to perform 2D-LC is broadly available to the analytical community in both industry and academia. Indeed, the technique can now be considered ready for application in R&D as well as in QA and QC labs, yet it is not widely known about outside academic laboratories and is rarely taught at the undergraduate level. This book outlines the main principles and features of 2D-LC (including comprehensive and heart-cutting modes, method development and real world applications) to enable modern analysts to start using this fascinating technique. The book offers an ideal starting point for those wishing to get into 2D-LC and will also be of interest to more experienced scientists in the field.
Author | : Hernan J. Cortes |
Publisher | : CRC Press |
Total Pages | : 424 |
Release | : 2020-07-24 |
Genre | : Science |
ISBN | : 1000104222 |
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This book summarizes all the important aspects of multidimensional separations, providing information on gas, liquid and thin-layer chromatography, as well as the techniques and applications of supercritical fluid chromatography in the multidimensional mode.
Author | : Ira S. Lurie |
Publisher | : |
Total Pages | : 0 |
Release | : 2017 |
Genre | : Designer drugs |
ISBN | : |
Download The Utility of Multi-dimensional Liquid Chromatography for the Analysis of Seized Drugs, Application to Emerging Drugs Book in PDF, ePub and Kindle