Molecular Oncology Underlying Mechanisms And Translational Advancements PDF Download
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| Author | : Ammad Ahmad Farooqi |
| Publisher | : Springer |
| Total Pages | : 302 |
| Release | : 2017-03-29 |
| Genre | : Medical |
| ISBN | : 3319530828 |
Download Molecular Oncology: Underlying Mechanisms and Translational Advancements Book in PDF, ePub and Kindle
Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity, dysregulation of spatio-temporally controlled signaling cascades, and loss of apoptosis are contributory in cancer development, progression and the development of resistance against different therapeutics. It is becoming progressively more understandable that earlier detection of pre-existing or emerging resistance against different therapeutics may prove to be helpful in personalizing the use of targeted cancer therapy. Despite the fact that there is a continuously increasing list of books, being guest edited by researchers, books on the subject are often composed of invited reviews without proper sequence and continuity and designed for a particular readership. This book progressively shifts and guides the readers from basic underlying mechanisms to translational approaches to treat cancer.
| Author | : Fabrizio d'Adda di Fagagna |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 274 |
| Release | : 2007-07-18 |
| Genre | : Medical |
| ISBN | : 0387691162 |
Download Advances in Molecular Oncology Book in PDF, ePub and Kindle
Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.
| Author | : Miguel H. Bronchud |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 429 |
| Release | : 2008-03-16 |
| Genre | : Medical |
| ISBN | : 1597454702 |
Download Principles of Molecular Oncology Book in PDF, ePub and Kindle
Drawing on years of significant advances and developments, the editors of this third edition have thoroughly updated the highly praised first and second editions and added new chapters to reflect the knowledge emerging from research on genomics, proteomics, chemoprevention strategies, pharmacogenomics, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small molecular-weight molecules.
| Author | : Javier Camacho |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 237 |
| Release | : 2012-02-07 |
| Genre | : Medical |
| ISBN | : 1608050165 |
Download Molecular Oncology Principles and Recent Advances Book in PDF, ePub and Kindle
"Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecu"
| Author | : CITTADINI |
| Publisher | : Birkhäuser |
| Total Pages | : 425 |
| Release | : 2013-11-21 |
| Genre | : Science |
| ISBN | : 3034856636 |
Download Molecular Oncology and Clinical Applications Book in PDF, ePub and Kindle
The basic knowledge of cell biology and molecular genetics in oncology is increasingly attracting the interest of clinical oncologists and is close to reaching a helpful application at the bedside. At present, it seems clear that the solution of the cancer problem lies within the comprehension of the intimate mechanisms leading to cell transformation and tumor progression as weIl as of the cancer-host relationship. According to this rationale every achievement in this context could drastically improve both diagnosis and therapy of neoplastic diseases. This={)ook represents the proceedings of the International Conference o~ Cancer: Biological Mechanisms and Clinical Applications, held in Rome on November 16-18, 1992. The meeting was organized by the Centro di Ricerche Oncologiche "Giovanni XXIII" of the Catholic University of Rome and the Consorzio Mario Negri Sud of S. M. Imbaro in collaboration with other colleagues from the Universities of Napoli and Bologna. As organizers and pmticipants to the Conference we think the meeting was a success, as was confirmed by the great interest raised in scientific and academic circles. The book collects contributions from leading scientists in all oncological m·eas ranging from molecular biology to immunology, diagnosis and therapy. The papers are organized into four sections: I - Molecular aspects of cell transformation and growth; II - Membrane receptors and signal transduction; III - Models for new therapeutical strategies; IV - Clinical Applications, following the strategy that chm·acterized the entire meeting: from molecule to bedside.
| Author | : Stefania Staibano |
| Publisher | : Springer |
| Total Pages | : 296 |
| Release | : 2013-11-27 |
| Genre | : Medical |
| ISBN | : 9789400771505 |
Download Prostate Cancer: Shifting from Morphology to Biology Book in PDF, ePub and Kindle
The aim of this book will be to contribute to the education of a new generation of experts in urology, molecular biology, pathology and oncology, offering them sufficient knowledge in basic and translational research to be fluency in the web of interacting networks playing a role in prostate cancer development, progression, metastasis and drug-resistance.The volume will cover the latest innovative researches in prostate cancer, with particular emphasis to the state-of-the-art analysis technologies that are essential for the accurate identification of molecular targets for disease diagnosis, molecular mechanisms of tumorigenesis, markers for susceptibility, molecular-based prognostic prevision, characterization of biomarkers of drug efficacy and drug resistance, validation of new therapeutics and diagnostics. Current advancements on the intersecting data concerning transcriptomes, proteomes, the molecular techniques referred as "omes", will be reported and discussed.
| Author | : Georg F. Weber |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 643 |
| Release | : 2007-09-12 |
| Genre | : Medical |
| ISBN | : 1402060165 |
Download Molecular Mechanisms of Cancer Book in PDF, ePub and Kindle
This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan, and the ability to invade surrounding tissue), protective mechanisms that prevent transformation (including DNA repair and epigenetic regulation), tumor-host interactions (with the endocrine system, the immune system, and blood vessel formation), and the underlying molecular defects of individual cancers.
| Author | : Miguel H. Bronchud |
| Publisher | : |
| Total Pages | : 732 |
| Release | : 2014-01-15 |
| Genre | : |
| ISBN | : 9781475762754 |
Download Principles of Molecular Oncology Book in PDF, ePub and Kindle
| Author | : Matthew Gregory Cable |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 132 |
| Release | : 2019-12-04 |
| Genre | : Medical |
| ISBN | : 1839680148 |
Download Osteosarcoma Book in PDF, ePub and Kindle
This book is titled Osteosarcoma - Diagnosis, Mechanisms, and Translational Developments, and focuses on recent advancements and novel ideas in osteosarcoma research. In a manner of speaking, we have taken the multidisciplinary mindset essential for treating osteosarcoma and broadened it to include other areas of cancer research. By learning from gains in other areas of oncology, such as new lncRNAs, the understanding of cancer metabolism and oxidative phosphorylation, and new chemotherapy agents, we can apply them to the niche of osteosarcoma for treatment development. By drawing more attention to these novel and clever discoveries, we hope to continue this enthusiasm for advancements in basic and translational research in the field of osteosarcoma.
| Author | : Ammad Ahmad Farooqi |
| Publisher | : Elsevier |
| Total Pages | : 340 |
| Release | : 2022-05-18 |
| Genre | : Science |
| ISBN | : 0128217898 |
Download Unraveling the Complexities of Metastasis Book in PDF, ePub and Kindle
Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism. This book is a valuable source for cancer researchers, medical doctors and several members of biomedical field who need to understand better the complex mechanism of metastasis. Explains the mechanism of metastasis from basic to advanced level through easy and comprehensive chapters written by internationally distinguished researchers Provides simplified version of important process of metastasis for the readers to comprehend the latest advancements made in the field Presents colorful diagrams to make different aspects of scientifically difficult topics easier for young researchers and newcomers in the field of cancer metastasis
