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Molecular Neurotoxicology

Molecular Neurotoxicology
Author: Nasser H. Zawia
Publisher: CRC Press
Total Pages: 330
Release: 2004-04-27
Genre: Medical
ISBN: 113446469X

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Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling deals with changes in gene expression following exposure to neurotoxicants, as well as deciphering signal transduction or transcription coupling that is altered by the same exposure. Until now, little has been published on the topic in one reference, and toxicol


Molecular Neurotoxicology

Molecular Neurotoxicology
Author: Nasser H. Zawia
Publisher: CRC Press
Total Pages: 236
Release: 2004-04-27
Genre: Medical
ISBN: 0203503317

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Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling deals with changes in gene expression following exposure to neurotoxicants, as well as deciphering signal transduction or transcription coupling that is altered by the same exposure. Until now, little has been published on the topic in one reference, and toxicol


Clinical Neurotoxicology E-Book

Clinical Neurotoxicology E-Book
Author: Michael R. Dobbs
Publisher: Elsevier Health Sciences
Total Pages: 729
Release: 2009-07-22
Genre: Medical
ISBN: 032307099X

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Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.


Neurotoxicology

Neurotoxicology
Author: Jean Harry G
Publisher: CRC Press
Total Pages: 404
Release: 1999-07-22
Genre: Medical
ISBN: 9781560327202

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This second edition of Neurotoxicology is valuable for scientists in government and industry who are responsible for public health and for the safe and efficient use of chemicals. This integrated approach to neurotoxicology will aid in the understanding of the sites and mechanisms of neurotoxicity, stimulate the formulation of testable hypotheses about how chemicals affect the nervous system, and help improve the risk assessment process. This edition focuses primarily on the neurobiological basis underlying neurotoxic sites and modes of action. The contents include: *molecular biological and in vitro approaches *potential cellular and molecular sites involving neuron-glia interactions *axonal transport *ion channels *metabolic influences on neurotoxicity *role of free radical formation in neurotoxicity *interaction between chemicals and trophic factors *endocrine disruptors *apoptosis in neurotoxicity *in vivo brain imaging *advances in measuring cognitive function *advances in developing quantitative models for neurotoxicology/risk assessment


Natural Molecules in Neuroprotection and Neurotoxicity

Natural Molecules in Neuroprotection and Neurotoxicity
Author: Marcos Roberto de Oliveira
Publisher: Elsevier
Total Pages: 2202
Release: 2023-11-24
Genre: Science
ISBN: 0443237646

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Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells


Handbook of Developmental Neurotoxicology

Handbook of Developmental Neurotoxicology
Author: William Slikker Jr.
Publisher: Academic Press
Total Pages: 618
Release: 2018-01-04
Genre: Science
ISBN: 0128093943

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Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts


Site-Selective Neurotoxicity

Site-Selective Neurotoxicity
Author: David S Lester
Publisher: CRC Press
Total Pages: 327
Release: 2002-02-07
Genre: Medical
ISBN: 0203219090

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This unique volume provides interdisciplinary coverage of the mechanistic perspective of neurotoxicity that focuses on the site of action of known neurotoxins. It provides the reader with an insight into the common characteristics of neurotoxin action on the nervous system and examines sites of action at three levels of complexity: molecular, cellu


Environmental Neurotoxicology

Environmental Neurotoxicology
Author: National Research Council
Publisher: National Academies Press
Total Pages: 167
Release: 1992-02-01
Genre: Science
ISBN: 0309045312

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Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.


Occupational Neurotoxicology

Occupational Neurotoxicology
Author:
Publisher: Academic Press
Total Pages: 330
Release: 2022-07-24
Genre: Medical
ISBN: 0128191775

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Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods. Provides updated information about exposure and neurotoxic outcomes Includes indication on new tools for neurobehavioral assessment Covers practical indications on preventive aspects