Molecular Mechanisms Of Neurodegeneration And Neuroprotection Experimental Approaches And The Diseased Brain PDF Download
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Author | : Reinhard Schliebs |
Publisher | : |
Total Pages | : |
Release | : 2004 |
Genre | : |
ISBN | : |
Download Molecular Mechanisms of Neurodegeneration and Neuroprotection - Experimental Approaches and the Diseased Brain Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 93 |
Release | : 2004 |
Genre | : |
ISBN | : |
Download International conference of the Molecular mechanisms of neurodegeneration and neuroprotection experimental approaches and the diseased brain, September 9-11 2004 Leipzig Book in PDF, ePub and Kindle
Author | : R. Schliebs |
Publisher | : |
Total Pages | : 159 |
Release | : 2004 |
Genre | : |
ISBN | : |
Download Molecular Mechanisms of Neurodegeneration Ans Neuroprotection Book in PDF, ePub and Kindle
Author | : Nagehan Ersoy Tunalı |
Publisher | : BoD – Books on Demand |
Total Pages | : 180 |
Release | : 2021-01-20 |
Genre | : Science |
ISBN | : 1838801499 |
Download Neurodegenerative Diseases Book in PDF, ePub and Kindle
Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical correlations, genetic aspects, neuropathological findings, and current therapeutic interventions in neurodegenerative diseases. I believe that this book will enlighten the curiosity for neurodegeneration and also encourage researchers to work on potentially effective molecular therapies for still mysterious neurodegenerative disorders.
Author | : Marie-Francoise Chesselet |
Publisher | : Springer Science & Business Media |
Total Pages | : 416 |
Release | : 2000-10-19 |
Genre | : Medical |
ISBN | : 1592590063 |
Download Molecular Mechanisms of Neurodegenerative Diseases Book in PDF, ePub and Kindle
With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.
Author | : Robert Crichton |
Publisher | : John Wiley & Sons |
Total Pages | : 628 |
Release | : 2013-09-04 |
Genre | : Medical |
ISBN | : 1118553519 |
Download Metal-Based Neurodegeneration Book in PDF, ePub and Kindle
Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scientific findings, including details of their biochemical actors (proteins or peptides), their normal and pathological conformations, and a description of the diseases characteristics, with an emphasis on the role of metal-induced oxidative stress, which can result in the production of intracellular aggregates of target proteins and peptides. Topics covered include: Brain function, physiology and the blood-brain barrier Immune system and neuroinflammation Aging and mild cognitive impairment, MCI Parkinson’s Disease Alzheimer’s Disease Creutzfelt-Jakob and related prion diseases Alcoholic Brain Damage Therapeutic strategies to combat the onset and progression of neurological diseases This extensively updated, full colour, second edition of Metal-based Neurodegeneration is an essential text for research scientists and clinicians working in gerontology, neuropathology, neurochemistry, and metalloprotein mechanisms.
Author | : Akhlaq A. Farooqui |
Publisher | : Bentham Science Publishers |
Total Pages | : 156 |
Release | : 2011-01-26 |
Genre | : Science |
ISBN | : 1608050920 |
Download Molecular Aspects of Neurodegeneration and Neuroprotection Book in PDF, ePub and Kindle
"Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occu"
Author | : Akhlaq A. Farooqui |
Publisher | : Academic Press |
Total Pages | : 404 |
Release | : 2020-09-07 |
Genre | : Medical |
ISBN | : 0128217014 |
Download Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders Book in PDF, ePub and Kindle
Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders
Author | : Tiziana Borsello |
Publisher | : Springer Science & Business Media |
Total Pages | : 498 |
Release | : 2007-08-08 |
Genre | : Medical |
ISBN | : 1588296660 |
Download Neuroprotection Methods and Protocols Book in PDF, ePub and Kindle
This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms.
Author | : Raymond Chuen-Chung Chang |
Publisher | : BoD – Books on Demand |
Total Pages | : 104 |
Release | : 2019-08-28 |
Genre | : Medical |
ISBN | : 1789847362 |
Download Neuroprotection Book in PDF, ePub and Kindle
Neuroprotection is a strategy to prevent or delay the progression of chronic neurodegenerative diseases, acute neurological disorders, or even mental disorders. The major aim of this book is to focus on different approaches to achieve neuroprotection. In this book, there are chapters discussing imidazoline ligands and opioid ligands in Alzheimer's disease, the beneficial effects of adenosine A2A receptor antagonist, adrenergic receptor agonists and antagonists modulating microglial responses, and different approaches to achieve neuroprotection against aging-associated macular degeneration. This book will give insights to scientists in the field to stimulate their research, medical professionals to review their clinical practices, and others who would like to learn more about different neuroprotective approaches.