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Molecular Genetic Analysis of Populations

Molecular Genetic Analysis of Populations
Author: A. R. Hoelzel
Publisher: Oxford University Press
Total Pages: 468
Release: 1998-03-19
Genre: Science
ISBN: 0191565601
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Methods enabling the direct study of genetic variation in natural populations have improved considerably. The new edition explores these updated techniques in DNA analysis and provides a revised and refined laboratory guide to investigating variation in DNA molecules.

Introduction to Genetic Analysis

Introduction to Genetic Analysis
Author: Anthony J.F. Griffiths
Publisher: Macmillan
Total Pages: 872
Release: 2008
Genre: Science
ISBN: 9780716768876
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Provides an introduction to genetic analysis. This book covers contemporary genetics, and helps students understand the essentials of genetics, featuring various experiments, teaching them how to analyze data, and how to draw their own conclusions

Molecular Genetic Approaches in Conservation

Molecular Genetic Approaches in Conservation
Author: Thomas B. Smith
Publisher: Oxford University Press
Total Pages: 498
Release: 1996-10-24
Genre: Science
ISBN: 0195344669
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Molecular techniques are proving invaluable in determining the phylogenetic status of potentially endangered species, for investigating mechanisms of speciation, and for measuring the genetic structure of populations. It is increasingly important for ecologists and evolutionary and conservation biologists to understand and use such molecular techniques, but most workers in these areas have not been trained in molecular biology. This book lays out the principles and basic techniques for the molecular tools appropriate for addressing issues in conservation, and it presents case studies showing how these tools have been used successfully in conservation biology. Examples include the genetic analysis of population structure, various uses of DNA in conservation genetics, and estimation of migration parameters from genetic data. Wildlife managers, as well as researchers in these areas, will find this a valuable book.

Genetic Analysis

Genetic Analysis
Author: Raphael Falk
Publisher: Cambridge University Press
Total Pages: 331
Release: 2009-05-14
Genre: Philosophy
ISBN: 0521884187
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There is a paradox lying at the heart of the study of heredity. To understand the ways in which features are passed on down from one generation to the next, we have to dig deeper and deeper into the ultimate nature of things - from organisms, to genes, to molecules. And yet as we do this, increasingly we find we are out of focus with our subjects. What has any of this to do with the living, breathing organisms with which we started? Organisms are living. Molecules are not. How do we relate one to the other? In Genetic Analysis, one of the most important empirical scientists in the field in the twentieth century attempts, through a study of history and drawing on his own vast experience as a practitioner, to face this paradox head-on. His book offers a deep and innovative understanding of our ways of thinking about heredity.

A Primer of Molecular Population Genetics

A Primer of Molecular Population Genetics
Author: Asher D. Cutter
Publisher: Oxford University Press
Total Pages: 266
Release: 2019-06-06
Genre: Science
ISBN: 0192575546
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What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

Mathematical and Statistical Methods for Genetic Analysis

Mathematical and Statistical Methods for Genetic Analysis
Author: Kenneth Lange
Publisher: Springer Science & Business Media
Total Pages: 376
Release: 2012-12-06
Genre: Medical
ISBN: 0387217509
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Written to equip students in the mathematical siences to understand and model the epidemiological and experimental data encountered in genetics research. This second edition expands the original edition by over 100 pages and includes new material. Sprinkled throughout the chapters are many new problems.

An Introduction to Genetic Analysis

An Introduction to Genetic Analysis
Author: Anthony J.F. Griffiths
Publisher: Macmillan
Total Pages: 808
Release: 2005
Genre: Science
ISBN: 9780716749394
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The eighth edition of 'An Introduction to Genetic Analysis' has been extensively revised, shaping its coverage to match current research and thinking in genetics.

Genetic Analysis

Genetic Analysis
Author: John R. S. Fincham
Publisher: John Wiley & Sons
Total Pages: 241
Release: 2009-05-27
Genre: Science
ISBN: 1444313827
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Authored by a very eminent geneticist, this text gives students a thorough appreciation of the development and potential of analytical genetic techniques. Beginning with a consideration of both the classical Mendelian and the molecular biological aspects of genetic analysis, the book goes on to discuss progress in three key areas of genetics. Firstly the elucidation of the detailed structure and overall organization of the genome, secondly the way that genetic differences at the molecular level account for heritable variation in populations, and finally an explanation of how the genes control the metabolism and development of the whole organism. Professor Fincham takes as his theme the links between classical and molecular genetics, and throughout the book shows how the combination of these two approaches can be a powerful tool for the advancement of genetic research. A clear and simple text from one of the world's leading geneticists Abundant and innovative illustrations Links classical Mendelian genetics with the new molecular genetic techniques

Molecular Ecology

Molecular Ecology
Author: Joanna R. Freeland
Publisher: John Wiley & Sons
Total Pages: 403
Release: 2006-03-30
Genre: Science
ISBN: 0470090634
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Molecular Ecology provides a comprehensive introduction to the many diverse aspects of this subject. The book unites theory with examples from a wide range of taxa in a logical and progressive manner, and its accessible writing style makes subjects such as population genetics and phylogenetics highly comprehensible to its readers. The first part of the book introduces the essential underpinnings of molecular ecology, starting with a review of genetics and a discussion of the molecular markers that are most frequently used in ecological research. This leads into an overview of population genetics in ecology. The second half of the book then moves on to specific applications of molecular ecology, covering phylogeography, behavioural ecology and conservation genetics. The final chapter looks at molecular ecology in a wider context by using a number of case studies that are relevant to various economic and social concerns, including wildlife forensics, agriculture, and overfishing * comprehensive overview of the different aspects of molecular ecology * attention to both theoretical and applied concerns * accessible writing style and logical structure * numerous up-to-date examples and references This will be an invaluable reference for those studying molecular ecology, population genetics, evolutionary biology, conservation genetics and behavioural ecology, as well as researchers working in these fields.

An Introduction to Statistical Genetic Data Analysis

An Introduction to Statistical Genetic Data Analysis
Author: Melinda C. Mills
Publisher: MIT Press
Total Pages: 433
Release: 2020-02-18
Genre: Science
ISBN: 0262538385
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A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.