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Missing Data Analysis in Practice

Missing Data Analysis in Practice
Author: Trivellore Raghunathan
Publisher: Chapman and Hall/CRC
Total Pages: 0
Release: 2015-10-19
Genre: Mathematics
ISBN: 9781482211924

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This book focuses on two general purpose approaches to data analysis that work well in practice: weighting and imputation. The book takes a very practical approach to the methods, with a number of datasets used to illustrate the key aspects. The datasets are taken from randomized trials, observational studies, and sample surveys. Keeping theoretical details to a minimum, the book is suitable for practitioners with only basic knowledge of statistics. The author’s SAS-based software, which can be used for all the examples, is available online.


Multiple Imputation of Missing Data in Practice

Multiple Imputation of Missing Data in Practice
Author: Yulei He
Publisher: CRC Press
Total Pages: 419
Release: 2021-11-20
Genre: Mathematics
ISBN: 0429530978

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Multiple Imputation of Missing Data in Practice: Basic Theory and Analysis Strategies provides a comprehensive introduction to the multiple imputation approach to missing data problems that are often encountered in data analysis. Over the past 40 years or so, multiple imputation has gone through rapid development in both theories and applications. It is nowadays the most versatile, popular, and effective missing-data strategy that is used by researchers and practitioners across different fields. There is a strong need to better understand and learn about multiple imputation in the research and practical community. Accessible to a broad audience, this book explains statistical concepts of missing data problems and the associated terminology. It focuses on how to address missing data problems using multiple imputation. It describes the basic theory behind multiple imputation and many commonly-used models and methods. These ideas are illustrated by examples from a wide variety of missing data problems. Real data from studies with different designs and features (e.g., cross-sectional data, longitudinal data, complex surveys, survival data, studies subject to measurement error, etc.) are used to demonstrate the methods. In order for readers not only to know how to use the methods, but understand why multiple imputation works and how to choose appropriate methods, simulation studies are used to assess the performance of the multiple imputation methods. Example datasets and sample programming code are either included in the book or available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book). Key Features Provides an overview of statistical concepts that are useful for better understanding missing data problems and multiple imputation analysis Provides a detailed discussion on multiple imputation models and methods targeted to different types of missing data problems (e.g., univariate and multivariate missing data problems, missing data in survival analysis, longitudinal data, complex surveys, etc.) Explores measurement error problems with multiple imputation Discusses analysis strategies for multiple imputation diagnostics Discusses data production issues when the goal of multiple imputation is to release datasets for public use, as done by organizations that process and manage large-scale surveys with nonresponse problems For some examples, illustrative datasets and sample programming code from popular statistical packages (e.g., SAS, R, WinBUGS) are included in the book. For others, they are available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book)


Missing Data Analysis in Practice

Missing Data Analysis in Practice
Author: Trivellore Raghunathan
Publisher: CRC Press
Total Pages: 227
Release: 2015-10-28
Genre: Mathematics
ISBN: 1482211939

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Missing Data Analysis in Practice provides practical methods for analyzing missing data along with the heuristic reasoning for understanding the theoretical underpinnings. Drawing on his 25 years of experience researching, teaching, and consulting in quantitative areas, the author presents both frequentist and Bayesian perspectives. He describes ea


Flexible Imputation of Missing Data, Second Edition

Flexible Imputation of Missing Data, Second Edition
Author: Stef van Buuren
Publisher: CRC Press
Total Pages: 444
Release: 2018-07-17
Genre: Mathematics
ISBN: 0429960352

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Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by multiple plausible values. The variability between these replacements reflects our ignorance of the true (but missing) value. Each of the completed data set is then analyzed by standard methods, and the results are pooled to obtain unbiased estimates with correct confidence intervals. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missing-data problem. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the MICE package as developed by the author. This new edition incorporates the recent developments in this fast-moving field. This class-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by verbal statements that explain the formula in accessible terms. The book sharpens the reader’s intuition on how to think about missing data, and provides all the tools needed to execute a well-grounded quantitative analysis in the presence of missing data.


The Prevention and Treatment of Missing Data in Clinical Trials

The Prevention and Treatment of Missing Data in Clinical Trials
Author: National Research Council
Publisher: National Academies Press
Total Pages: 163
Release: 2010-12-21
Genre: Medical
ISBN: 030918651X

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Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.


Clinical Trials with Missing Data

Clinical Trials with Missing Data
Author: Michael O'Kelly
Publisher: John Wiley & Sons
Total Pages: 472
Release: 2014-02-14
Genre: Medical
ISBN: 1118762533

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This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable. The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively. The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included – the reader is given a toolbox for implementing analyses under a variety of assumptions.


Missing Data in Clinical Studies

Missing Data in Clinical Studies
Author: Geert Molenberghs
Publisher: John Wiley & Sons
Total Pages: 526
Release: 2007-04-04
Genre: Medical
ISBN: 9780470510438

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Missing Data in Clinical Studies provides a comprehensive account of the problems arising when data from clinical and related studies are incomplete, and presents the reader with approaches to effectively address them. The text provides a critique of conventional and simple methods before moving on to discuss more advanced approaches. The authors focus on practical and modeling concepts, providing an extensive set of case studies to illustrate the problems described. Provides a practical guide to the analysis of clinical trials and related studies with missing data. Examines the problems caused by missing data, enabling a complete understanding of how to overcome them. Presents conventional, simple methods to tackle these problems, before addressing more advanced approaches, including sensitivity analysis, and the MAR missingness mechanism. Illustrated throughout with real-life case studies and worked examples from clinical trials. Details the use and implementation of the necessary statistical software, primarily SAS. Missing Data in Clinical Studies has been developed through a series of courses and lectures. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations. Graduate students of biostatistics will also find much of benefit.


Applied Missing Data Analysis in the Health Sciences

Applied Missing Data Analysis in the Health Sciences
Author: Xiao-Hua Zhou
Publisher: John Wiley & Sons
Total Pages: 260
Release: 2014-06-30
Genre: Medical
ISBN: 0470523816

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A modern and practical guide to the essential concepts and ideas for analyzing data with missing observations in the field of biostatistics With an emphasis on hands-on applications, Applied Missing Data Analysis in the Health Sciences outlines the various modern statistical methods for the analysis of missing data. The authors acknowledge the limitations of established techniques and provide newly-developed methods with concrete applications in areas such as causal inference methods and the field of diagnostic medicine. Organized by types of data, chapter coverage begins with an overall introduction to the existence and limitations of missing data and continues into traditional techniques for missing data inference, including likelihood-based, weighted GEE, multiple imputation, and Bayesian methods. The book’s subsequently covers cross-sectional, longitudinal, hierarchical, survival data. In addition, Applied Missing Data Analysis in the Health Sciences features: Multiple data sets that can be replicated using the SAS®, Stata®, R, and WinBUGS software packages Numerous examples of case studies in the field of biostatistics to illustrate real-world scenarios and demonstrate applications of discussed methodologies Detailed appendices to guide readers through the use of the presented data in various software environments Applied Missing Data Analysis in the Health Sciences is an excellent textbook for upper-undergraduate and graduate-level biostatistics courses as well as an ideal resource for health science researchers and applied statisticians.


Applied Missing Data Analysis

Applied Missing Data Analysis
Author: Craig K. Enders
Publisher: Guilford Press
Total Pages: 401
Release: 2010-04-23
Genre: Psychology
ISBN: 1606236393

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Walking readers step by step through complex concepts, this book translates missing data techniques into something that applied researchers and graduate students can understand and utilize in their own research. Enders explains the rationale and procedural details for maximum likelihood estimation, Bayesian estimation, multiple imputation, and models for handling missing not at random (MNAR) data. Easy-to-follow examples and small simulated data sets illustrate the techniques and clarify the underlying principles. The companion website includes data files and syntax for the examples in the book as well as up-to-date information on software. The book is accessible to substantive researchers while providing a level of detail that will satisfy quantitative specialists. This book will appeal to researchers and graduate students in psychology, education, management, family studies, public health, sociology, and political science. It will also serve as a supplemental text for doctoral-level courses or seminars in advanced quantitative methods, survey analysis, longitudinal data analysis, and multilevel modeling, and as a primary text for doctoral-level courses or seminars in missing data.


Missing Data in Longitudinal Studies

Missing Data in Longitudinal Studies
Author: Michael J. Daniels
Publisher: CRC Press
Total Pages: 324
Release: 2008-03-11
Genre: Mathematics
ISBN: 1420011189

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Drawing from the authors' own work and from the most recent developments in the field, Missing Data in Longitudinal Studies: Strategies for Bayesian Modeling and Sensitivity Analysis describes a comprehensive Bayesian approach for drawing inference from incomplete data in longitudinal studies. To illustrate these methods, the authors employ