Mass Spectrometry Of Protein Interactions PDF Download
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Author | : M. Chance |
Publisher | : John Wiley & Sons |
Total Pages | : 325 |
Release | : 2008-09-22 |
Genre | : Science |
ISBN | : 0470258861 |
Download Mass Spectrometry Analysis for Protein-Protein Interactions and Dynamics Book in PDF, ePub and Kindle
Presents a wide variety of mass spectrometry methods used to explore structural mechanisms, protein dynamics and interactions between proteins. Preliminary chapters cover mass spectrometry methods for examining proteins and are then followed by chapters devoted to presenting very practical, how-to methods in a detailed way. Includes footprinting and plistex specifically, setting this book apart from the competition.
Author | : Kevin Downard |
Publisher | : John Wiley & Sons |
Total Pages | : 153 |
Release | : 2007-08-24 |
Genre | : Science |
ISBN | : 047014632X |
Download Mass Spectrometry of Protein Interactions Book in PDF, ePub and Kindle
The authoritative guide to analyzing protein interactions by mass spectrometry Mass spectrometry (MS) is playing an increasingly important role in the study of protein interactions. Mass Spectrometry of Protein Interactionspresents timely and definitive discussions of the diverse range of approaches for studying protein interactions by mass spectrometry with an extensive set of references to the primary literature. Each chapter is written by authors or teams of authors who are international authorities in their fields. This leading reference text: * Discusses the direct detection of protein interactions through electrospray ionization (ESI-MS); ion mobility analysis; and matrix-assisted laser desorption/ionization (MALDI-MS) * Covers the indirect analysis of protein interactions through hydrogen-deuterium exchange (HX-MS); limited proteolysis; cross-linking; and radial probe (RP-MS) * Guides researchers in the use of mass spectrometry in structural biology, biochemistry, and protein science to map and define the huge number and diversity of protein interactions * Reviews the latest discoveries and applications and addresses new and ongoing challenges This is a comprehensive reference for researchers in academia and industry engaged in studies of protein interactions and an excellent text for graduate and postgraduate students.
Author | : Gabriel Waksman |
Publisher | : Springer Science & Business Media |
Total Pages | : 325 |
Release | : 2006-12-22 |
Genre | : Medical |
ISBN | : 0387245324 |
Download Proteomics and Protein-Protein Interactions Book in PDF, ePub and Kindle
Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street London WC1E 7H United Kingdom Email: g. waksman@bbk. ac. uk and g. waksman@ucl. ac. uk Phone: (+44) (0) 207 631 6833 Fax: (+44) (0) 207 631 6833 URL: http://people. cryst. bbk. ac. uk/?ubcg54a Gabriel Waksman is Professor of Structural Molecular Biology at the Institute of Structural Molecular Biology at UCL/Birkbeck, of which he is also the director. Before joining the faculty of UCL and Birkbeck, he was the Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics at the Washington University School of Medicine in St Louis (USA). The rapidly evolving ?eld of protein science has now come to realize the ubiquity and importance of protein–protein interactions. It had been known for some time that proteins may interact with each other to form functional complexes, but it was thought to be the property of only a handful of key proteins. However, with the advent of hi- throughput proteomics to monitor protein–protein interactions at an organism level, we can now safely state that protein–protein interactions are the norm and not the exception.
Author | : Shahid Mukhtar |
Publisher | : Springer Nature |
Total Pages | : 480 |
Release | : 2023-07-14 |
Genre | : Science |
ISBN | : 1071633279 |
Download Protein-Protein Interactions Book in PDF, ePub and Kindle
This detailed volume provides a comprehensive collection of classic and cutting-edge methods and techniques in mapping protein-protein interactions. The chapters include a variety of in vitro and in vivo experimental methods covering cell biology, biochemistry, and biophysics. In addition, the book also explores in silico methods including sequence-, structure-, and phylogenetic profile-based approaches as well as gene expression and machine learning methods. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein-Protein Interactions: Methods and Protocols serves as an ideal guide for researchers working in protein science and beyond.
Author | : Julian Whitelegge |
Publisher | : Elsevier |
Total Pages | : 563 |
Release | : 2008-10-09 |
Genre | : Science |
ISBN | : 0080932037 |
Download Protein Mass Spectrometry Book in PDF, ePub and Kindle
This book is designed to be a central text for young graduate students interested in mass spectrometry as it relates to the study of protein structure and function as well as proteomics. It is a definite must-have work for:- libraries at academic institutions with Master and Graduate programs in biochemistry, molecular biology, structural biology and proteomics- individual laboratories with interests covering these areas - libraries and individual laboratories in the pharmaceutical and biotechnology industries. *Serves as an essential reference to those working in the field*Incorporates the contributions of prominent experts *Features comprehensive coverage and a logical structure
Author | : Anna Panchenko |
Publisher | : Springer Science & Business Media |
Total Pages | : 198 |
Release | : 2010-04-06 |
Genre | : Science |
ISBN | : 1848001258 |
Download Protein-protein Interactions and Networks Book in PDF, ePub and Kindle
The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse data on protein-protein interactions and protein interaction networks.
Author | : Jennifer Nina Sutton |
Publisher | : |
Total Pages | : 244 |
Release | : 2003 |
Genre | : |
ISBN | : |
Download Characterization of Peptide Antigens and Protein-protein Interactions by Mass Spectrometry Book in PDF, ePub and Kindle
Author | : Peter Schuck |
Publisher | : Springer Science & Business Media |
Total Pages | : 537 |
Release | : 2007-03-20 |
Genre | : Science |
ISBN | : 0387359664 |
Download Protein Interactions Book in PDF, ePub and Kindle
This volume successfully and clearly examines how biophysical approaches can be used to study complex systems of reversibly interacting proteins. It deals with the methodology behind the research and shows how to synergistically incorporate several methodologies for use. Each chapter treats and introduces the reader to different biological systems, includes a brief summary of the physical principles, and mentions practical requirements.
Author | : Chava Lifshitz |
Publisher | : John Wiley & Sons |
Total Pages | : 707 |
Release | : 2006-10-27 |
Genre | : Science |
ISBN | : 0470050411 |
Download Principles of Mass Spectrometry Applied to Biomolecules Book in PDF, ePub and Kindle
An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques.
Author | : Michael L. Gross |
Publisher | : John Wiley & Sons |
Total Pages | : 484 |
Release | : 2011-09-26 |
Genre | : Medical |
ISBN | : 1118116542 |
Download Protein and Peptide Mass Spectrometry in Drug Discovery Book in PDF, ePub and Kindle
The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.