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| Author | : Friedemann Honecker |
| Publisher | : MDPI |
| Total Pages | : 120 |
| Release | : 2018-10-02 |
| Genre | : |
| ISBN | : 3038421316 |
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
| Author | : Friedemann Honecker |
| Publisher | : MDPI |
| Total Pages | : 119 |
| Release | : 2018-06-26 |
| Genre | : Electronic books |
| ISBN | : 3038427659 |
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
| Author | : Friedemann Honecker |
| Publisher | : Mdpi AG |
| Total Pages | : 480 |
| Release | : 2021-06-11 |
| Genre | : Science |
| ISBN | : 9783036506302 |
The very first marine-derived anticancer drug, Cytarabine (aka Ara-C, Cytosar-U(R)), was approved by the FDA in 1969 for the treatment of leukemia. At the beginning of 2021, the list of approved marine-derived anticancer drugs consists of nine substances, five of which received approval within the last two years, demonstrating the rapid evolution of the field. The current book is a collection of scientific articles related to the exponentially growing field of anticancer marine compounds. These articles cover the whole field, from agents with cancer-preventive activity, to novel and previously characterized compounds with anticancer activity, both in vitro and in vivo, as well as the latest status of compounds under clinical development.
| Author | : |
| Publisher | : Mdpi AG |
| Total Pages | : 756 |
| Release | : 2015-11-23 |
| Genre | : Health & Fitness |
| ISBN | : 9783038421320 |
This book is based on a Special Issue called "Marine Compounds and Cancer" (http: //www.mdpi.com/journal/marinedrugs/special_issues/marine-compounds-cancer) of the open access journal, Marine Drugs (ISSN 1660-3397), which was running for two years (2013-2015). It comprises 39 articles in total, a quarter of which are reviews, summarizing the current state of the art in different topics of marineanti-cancer agents. It covers the full scope from agents with cancer-preventive activity, to novel and previously characterized compounds with anti-canceractivity, both in vitro and in vivo, and the latest status of clinical development of marine agents used in clinical trials.
| Author | : Friedemann Honecker |
| Publisher | : |
| Total Pages | : |
| Release | : 2018 |
| Genre | : |
| ISBN | : 9783038427667 |
Marine Compounds and Cancer 2017.
| Author | : Se-Kwon Kim |
| Publisher | : Springer |
| Total Pages | : 801 |
| Release | : 2014-11-27 |
| Genre | : Science |
| ISBN | : 3319071459 |
This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
| Author | : Pandurangan, Ashok Kumar |
| Publisher | : IGI Global |
| Total Pages | : 643 |
| Release | : 2022-03-18 |
| Genre | : Medical |
| ISBN | : 1799892603 |
Many chemotherapeutic agents are available in today’s market that are highly effective against a variety of cancer types; however, the major drawbacks of these chemotherapeutic agents are the many side effects. As an alternative to these chemotherapeutic agents, there are a number of natural agents that are effective against cancer that have been tested in preclinical and clinical models over the years. These natural products must be documented and discussed in order to provide a thorough overview of all the options available for cancer treatment. The Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics emphasizes the list of natural agents against all types of cancers and discusses the current state of research in the fields of natural products and their derivatives against cancer in preclinical and clinical models. This book also provides insight into the applications of meditation and mindfulness-based interventions in clinical and non-clinical conditions. Covering topics such as cancer therapy, antioxidants, and flavonoids, it is ideal for students, research scholars, academicians, professors, scientists, oncologists, doctors, and medical practitioners.
| Author | : Ramasamy Santhanam |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 386 |
| Release | : 2024-08-08 |
| Genre | : Medical |
| ISBN | : 9815256068 |
This inter-disciplinary volume provides information on anticancer medicines derived from marine organisms. Eight edited reviews extensively list the variety of organisms including marine plants, sponges, cnidarians and fish. Emphasis is placed on the source of the compounds, their structure and mechanism of action. Anticancer peptides from sponges are covered in a dedicated chapter. The specific biology and ecology of marine organisms yielding these anticancer compounds is also highlighted where appropriate. All chapters include detailed references for advanced readers. This volume is a standard text-cum-reference for teachers, students and researchers of various disciplines such as Biomedical Sciences, Pharmaceutical Sciences, Marine Biology, and Fisheries Science, it also serves as a guide to marine anticancer compounds for professionals in the pharmaceutical industry who are involved in the development of new marine-derived anticancer drugs.
| Author | : Celso Alves |
| Publisher | : Mdpi AG |
| Total Pages | : 0 |
| Release | : 2023-06-12 |
| Genre | : |
| ISBN | : 9783036575681 |
Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, "Marine Natural Products as Anticancer Agents 2.0", gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents.
| Author | : Celso Alves |
| Publisher | : Mdpi AG |
| Total Pages | : 166 |
| Release | : 2021-11-12 |
| Genre | : Medical |
| ISBN | : 9783036518206 |
Cancer remains one of the most significant threats to human health and one of the deadliest diseases worldwide, making it crucial to develop new drugs. Over the last few decades, natural products have become one of the key drivers in the development of innovative cancer treatments. Despite drug development from terrestrial resources, the marine environment only recently emerged as a prolific source of unparalleled structurally active metabolites. Due to their excellent scaffold diversity, structural complexity, and ability to act on multiple cell signaling networks involved in carcinogenesis, marine natural products (MNPs) are ideal candidates to inspire the development of novel anticancer medicines. This book gathers nine publications of the Special Issue "Marine Natural Products as Anticancer Agents," providing an excellent overview of the chemical richness offered by marine organisms, such as sponges, myxobacteria, fungi, and soft corals. MNPs or derived products belong to distinct chemical classes, including terpenoids, alkaloids, cyclodepsipeptides, polyketides, and hydroxyphenylacetic acid derivatives. These compounds modulate cancer cell mechanisms in in vitro and in vivo models, exhibiting high specificity and great affinity to interact with biological targets linked to specific intracellular signaling pathways, including mitochondrial dysfunction, autophagy, endoplasmic reticulum stress induction, apoptosis, inflammation, migration, and invasion. This volume provides an exciting overview of marine natural products as potential therapeutic agents for cancer treatment.
