Kernel Ridge Regression In Clinical Research PDF Download
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Author | : Ton J. Cleophas |
Publisher | : Springer Nature |
Total Pages | : 292 |
Release | : 2022-09-12 |
Genre | : Science |
ISBN | : 3031107179 |
Download Kernel Ridge Regression in Clinical Research Book in PDF, ePub and Kindle
IBM (international business machines) has published in its SPSS statistical software 2022 update a very important novel regression method entitled Kernel Ridge Regression (KRR). It is an extension of the currently available regression methods, and is suitable for pattern recognition in high dimensional data, particularly, when alternative methods fail. Its theoretical advantages are plenty and include the kernel trick for reduced arithmetic complexity, estimation of uncertainty by Gaussians unlike histograms, corrected data-overfit by ridge regularization, availability of 8 alternative kernel density models for datafit. A very exciting and wide array of preliminary KRR research has already been published by major disciplines (like studies in quantum mechanics and nuclear physics, studies of molecular affinity / dynamics, atomisation energy studies, but also forecasting economics studies, IoT (internet of things) studies for e-networks, plant stress response studies, big data streaming studies, etc). In contrast, it is virtually unused in clinical research. This edition is the first textbook and tutorial of kernel ridge regressions for medical and healthcare students as well as recollection / update bench, and help desk for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional regression analyses. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern KRR methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 24 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.
Author | : Ton J. Cleophas |
Publisher | : Springer Nature |
Total Pages | : 230 |
Release | : 2023-05-29 |
Genre | : Medical |
ISBN | : 3031316320 |
Download Modern Survival Analysis in Clinical Research Book in PDF, ePub and Kindle
An important novel menu for Survival Analysis entitled Accelerated Failure Time (AFT) models has been published by IBM (international Businesss Machines) in its SPSS statistical software update of 2023. Unlike the traditional Cox regressions that work with hazards, which are the ratio of deaths and non-deaths in a sample, it works with risk of death, which is the proportion of deaths in the same sample. The latter approach may provide better sensitivity of testing, but has been seldom applied, because with computers risks are tricky and hazards because they are odds are fine. This was underscored in 1997 by Keiding and colleague statisticians from Copenhagen University who showed better-sensitive goodness of fit and null-hypothesis tests with AFT than with Cox survival tests. So far, a controlled study of a representative sample of clinical Kaplan Meier assessments, where the sensitivity of Cox regression is systematically tested against that of AFT modeling, has not been accomplished. This edition is the first textbook and tutorial of AFT modeling both for medical and healthcare students and for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional Cox regressions. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern data analysis methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 25 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.
Author | : Ton J. Cleophas |
Publisher | : Springer Nature |
Total Pages | : 283 |
Release | : 2022-01-17 |
Genre | : Medical |
ISBN | : 3030828409 |
Download Quantile Regression in Clinical Research Book in PDF, ePub and Kindle
Quantile regression is an approach to data at a loss of homogeneity, for example (1) data with outliers, (2) skewed data like corona - deaths data, (3) data with inconstant variability, (4) big data. In clinical research many examples can be given like circadian phenomena, and diseases where spreading may be dependent on subsets with frailty, low weight, low hygiene, and many forms of lack of healthiness. Stratified analyses is the laborious and rather explorative way of analysis, but quantile analysis is a more fruitful, faster and completer alternative for the purpose. Considering all of this, we are on the verge of a revolution in data analysis. The current edition is the first textbook and tutorial of quantile regressions for medical and healthcare students as well as recollection/update bench, and help desk for professionals. Each chapter can be studied as a standalone and covers one of the many fields in the fast growing world of quantile regressions. Step by step analyses of over 20 data files stored at extras.springer.com are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology(2000-2002). From their expertise they should be able to make adequate selections of modern quantile regression methods for the benefit of physicians, students, and investigators.
Author | : Yun Zheng |
Publisher | : Frontiers Media SA |
Total Pages | : 172 |
Release | : 2020-11-04 |
Genre | : Science |
ISBN | : 2889660540 |
Download Recent Progresses of Non-Coding RNAs in Biological and Medical Research, 2nd Edition Book in PDF, ePub and Kindle
Publisher’s note: In this 2nd edition, the following article has been updated: Xun Y, Tang Y, Hu L, Xiao H, Long S, Gong M, Wei C, Wei K and Xiang S (2019) Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation. Front. Genet. 10:778. doi: 10.3389/fgene.2019.00778
Author | : Nikos Paragios |
Publisher | : Springer |
Total Pages | : 501 |
Release | : 2015-03-24 |
Genre | : Computers |
ISBN | : 038709749X |
Download Handbook of Biomedical Imaging Book in PDF, ePub and Kindle
This book offers a unique guide to the entire chain of biomedical imaging, explaining how image formation is done, and how the most appropriate algorithms are used to address demands and diagnoses. It is an exceptional tool for radiologists, research scientists, senior undergraduate and graduate students in health sciences and engineering, and university professors.
Author | : De-Shuang Huang |
Publisher | : Springer |
Total Pages | : 806 |
Release | : 2017-07-18 |
Genre | : Computers |
ISBN | : 3319633090 |
Download Intelligent Computing Theories and Application Book in PDF, ePub and Kindle
This three-volume set LNCS 10361, LNCS 10362, and LNAI 10363 constitutes the refereed proceedings of the 13th International Conference on Intelligent Computing, ICIC 2017, held in Liverpool, UK, in August 2017. The 212 full papers and 20 short papers of the three proceedings volumes were carefully reviewed and selected from 612 submissions. This first volume of the set comprises 71 papers. The papers are organized in topical sections such as Evolutionary Computation and Learning; Neural Networks; Nature Inspired Computing and Optimization; Signal Processing; Pattern Recognition; Biometrics Recognition; Image Processing; Information Security; Virtual Reality and Human-Computer Interaction; Business Intelligence and Multimedia Technology; Genetic Algorithms; Biomedical Informatics Theory and Methods; Particle Swarm Optimization and Niche Technology; Swarm Intelligence and Optimization; Independent Component Analysis; Compressed Sensing and Sparse Coding; Natural Computing; Intelligent Computing in Computer Vision; Computational Intelligence and Security for Image Applications in Social Network; Neural Networks: Theory and Application.
Author | : Nicholas Ayache |
Publisher | : Springer Science & Business Media |
Total Pages | : 807 |
Release | : 2012-09-22 |
Genre | : Computers |
ISBN | : 3642334156 |
Download Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2012 Book in PDF, ePub and Kindle
The three-volume set LNCS 7510, 7511, and 7512 constitutes the refereed proceedings of the 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012, held in Nice, France, in October 2012. Based on rigorous peer reviews, the program committee carefully selected 252 revised papers from 781 submissions for presentation in three volumes. The first volume includes 91 papers organized in topical sections on abdominal imaging, computer-assisted interventions and robotics; computer-aided diagnosis and planning; image reconstruction and enhancement; analysis of microscopic and optical images; computer-assisted interventions and robotics; image segmentation; cardiovascular imaging; and brain imaging: structure, function and disease evolution.
Author | : Isaac Woungang |
Publisher | : Springer Nature |
Total Pages | : 693 |
Release | : 2023-03-21 |
Genre | : Computers |
ISBN | : 3031281837 |
Download Advanced Network Technologies and Intelligent Computing Book in PDF, ePub and Kindle
This book constitutes the refereed proceedings of the Second International Conference on Advanced Network Technologies and Intelligent Computing, ANTIC 2022, held in Varanasi, India, during December 22–24, 2022. The 68 full papers and 11 short papers included in this book were carefully reviewed and selected from 443 submissions. They were organized in two topical sections as follows: Advanced Network Technologies and Intelligent Computing.
Author | : Ashish Khanna |
Publisher | : Academic Press |
Total Pages | : 311 |
Release | : 2021-03-10 |
Genre | : Science |
ISBN | : 0128204516 |
Download Applications of Big Data in Healthcare Book in PDF, ePub and Kindle
Applications of Big Data in Healthcare: Theory and Practice begins with the basics of Big Data analysis and introduces the tools, processes and procedures associated with Big Data analytics. The book unites healthcare with Big Data analysis and uses the advantages of the latter to solve the problems faced by the former. The authors present the challenges faced by the healthcare industry, including capturing, storing, searching, sharing and analyzing data. This book illustrates the challenges in the applications of Big Data and suggests ways to overcome them, with a primary emphasis on data repositories, challenges, and concepts for data scientists, engineers and clinicians. The applications of Big Data have grown tremendously within the past few years and its growth can not only be attributed to its competence to handle large data streams but also to its abilities to find insights from complex, noisy, heterogeneous, longitudinal and voluminous data. The main objectives of Big Data in the healthcare sector is to come up with ways to provide personalized healthcare to patients by taking into account the enormous amounts of already existing data. Provides case studies that illustrate the business processes underlying the use of big data and deep learning health analytics to improve health care delivery Supplies readers with a foundation for further specialized study in clinical analysis and data management Includes links to websites, videos, articles and other online content to expand and support the primary learning objectives for each major section of the book
Author | : Jianzhong Su |
Publisher | : Frontiers Media SA |
Total Pages | : 465 |
Release | : 2021-02-24 |
Genre | : Science |
ISBN | : 2889665046 |
Download Computational Epigenetics in Human Diseases, Cell Differentiation, and Cell Reprogramming, Volume I Book in PDF, ePub and Kindle