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Inheritance of Kidney and Urinary Tract Diseases

Inheritance of Kidney and Urinary Tract Diseases
Author: Adrian Spitzer
Publisher: Springer Science & Business Media
Total Pages: 453
Release: 2012-12-06
Genre: Medical
ISBN: 1461316030

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Genetic disorders have emerged as a prominent cause of morbidity and mor tality among infants and adults. As many as 10% to 20% of hospital admis sions and at least 10% of the mortality in this age group are due to inherited diseases. There are at least two factors that have brought genetic disorders into the forefront of pediatrics. One is a great reduction in childhood mortality due to infections and nutritional deficiency states, and the other is the rapid progress made in the identification of genetic defects. Amniocentesis, chorionic villus sampling, and recombinant DNA technology have already had a tremendous impact on the practice of medicine. This is why the first two chapters of this volume are dedicated to general principles of molecular genetics and to a description of the techniques used to diagnose genetic disorders at the DNA level. The relevance of this new area of science to the study of inherited renal diseases is reflected in the large body of knowledge that has been generated regarding the association between various glomerular nephritides and genetic markers such as the HLA system, and even more impressively in the direct or indirect identification of abnormal genes or gene products in Alport's syn drome, autosomal dominant polycystic kidney disease, and Lowe's syndrome. These discoveries figure prominently in the pages of this book. Yet, the progress we have made has barely scratched the surface of the problem.


Molecular and Genetic Basis of Renal Disease E-Book

Molecular and Genetic Basis of Renal Disease E-Book
Author: David B. Mount
Publisher: Elsevier Health Sciences
Total Pages: 606
Release: 2007-10-25
Genre: Medical
ISBN: 1437710379

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This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.


Genetic Diseases of the Kidney

Genetic Diseases of the Kidney
Author: Richard P. Lifton
Publisher: Academic Press
Total Pages: 895
Release: 2009-02-25
Genre: Science
ISBN: 0080924271

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Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and kidney disease. Genetic abnormalities are carefully presented within the appropriate physiologic context so that readers will understand not only which genes are linked to which diseases but also which pathways lead from a genetic “disturbance to the systemic appearance of disease. Lays the essential foundation of mammalian genetics principles for medical professionals with little or no background in genetics Analyzes specific renal diseases – both monogenic disorders confined to the kidney and systemic diseases with renal involvement – and explains their genetic causes World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension)


Disease Control Priorities in Developing Countries

Disease Control Priorities in Developing Countries
Author: Dean T. Jamison
Publisher: World Bank Publications
Total Pages: 1449
Release: 2006-04-02
Genre: Medical
ISBN: 0821361805

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Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.


Inherited Disorders of the Kidney

Inherited Disorders of the Kidney
Author: Stephen H. Morgan
Publisher:
Total Pages: 654
Release: 1998
Genre: Medical
ISBN:

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A high proportion of adults with end-stage renal failure are suffering from an inherited disorder of the kidneys. This is the first book to present a practical approach to the investigation and management of people with inherited renal disorders. Taking an international perspective, it covers the dramatic clinical and scientific advances that have been made in the past decade.


Congenital Anomalies of the Kidney and Urinary Tract

Congenital Anomalies of the Kidney and Urinary Tract
Author: Amin J. Barakat
Publisher: Springer
Total Pages: 373
Release: 2016-06-08
Genre: Medical
ISBN: 3319292196

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This comprehensive, easy to read reference addresses the clinical implications of congenital anomalies of the kidney and urinary tract (CAKUT) in children. Authored by a panel of internationally recognized pediatric nephrologists and urologists, chapters discuss clinical presentation, workup, interpretation of imaging studies, genetics, prenatal diagnosis, prevention and treatment of various anomalies to help the practitioner understand, diagnose and manage CAKUT. Tables, figures, algorithms and an extensive appendix listing conditions and syndromes associated with CAKUT are featured to assist physicians in the differential diagnosis and workup of different conditions.


Genetics of Kidney Diseases

Genetics of Kidney Diseases
Author: Harvest F. Gu
Publisher: Frontiers Media SA
Total Pages: 119
Release: 2020-05-22
Genre:
ISBN: 2889637379

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Kidney Disease and Urinary Tract Disorders Sourcebook, Fourth Edition

Kidney Disease and Urinary Tract Disorders Sourcebook, Fourth Edition
Author: James Chambers
Publisher:
Total Pages: 0
Release: 2024-12
Genre: Health & Fitness
ISBN: 9780780821620

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Millions of Americans experience difficulties involving the kidneys, ureters, bladder, and urethra--the components of the urinary system. Problems can be caused by illness, injury, genetics, or aging and include disorders such as urinary incontinence, urinary tract infections and cancers, kidney stones, and kidney failure. According to the Centers for Disease Control and Prevention (CDC), about 37 million U.S. adults are estimated to have chronic kidney disease (CKD), and most of them do not know they have it. Although kidney disease and urinary tract disorders can have a significant impact on a person's physical, emotional, and social well-being, recent medical advances offer the promise of more effective treatments and they provide the means by which those affected can learn to cope more successfully with related challenges. Additionally, by understanding the risk factors associated with these types of disorders, people can make lifestyle adjustments and take preventive measures to preserve urological health. Kidney Disease and Urinary Tract Disorders Sourcebook, Fourth Edition provides information about the vital organs of the urinary system and explains how they work. It talks about the causes, symptoms, diagnosis, and treatment of various problems that impact the kidney and urinary system, including acute kidney injury, bladder stones, chronic kidney disease, kidney cysts, kidney stones, solitary kidney, urethral stricture, urinary tract infections (UTIs), and so on. It also discusses the genetic and congenital disorders along with the cancers that affect the kidneys and urinary tract. Various diagnostic tests such as creatinine test, blood urea nitrogen test, cystatin marker test, kidney biopsy, renal panel test, urine test, and urinary tract imaging that are used to detect kidney disease are also discussed in detail. It explains the treatments used to replace lost kidney function such as hemodialysis, peritoneal dialysis, and kidney transplantation. Information about Medicare coverage available for dialysis and kidney transplant service is also provided. The book concludes with a glossary of related terms, and a directory of additional resources that provide help and information to patients with kidney disease and urinary tract disorders. Part 1: Understanding the Urinary System provides information about the vital organs of the urinary system and explains how they work. It talks about risk factors for kidney disease and provides statistical data on the prevalence of kidney disease in the United States. Part 2: Acute and Chronic Kidney Diseases focuses on diseases and disorders affecting the kidneys, including acute kidney injury, chronic kidney disease, kidney cysts, renal artery stenosis, and diabetes insipidus. Kidney diseases that affect children are also explained in detail along with the information about immune disorders of kidney. Part 3: Diagnostic Tests for Kidney Disease provides information about various tests used to diagnose kidney disease such as creatinine test, blood urea nitrogen test, cystatin marker test, kidney biopsy, renal panel test, urine test, and urinary tract imaging. Part 4: Disorders of the Urinary Tract provides an overview about urinary tract infections (UTIs) and explains how they can affect adults, children, and pregnant women. Facts about novel treatment approach and complementary therapy for UTI are also provided. It provides information about various other disorders of the urinary tract such as solitary kidney, glomerular diseases, amyloidosis, urethral stricture, and so on. The congenital defects of the urinary tract and genitals are also explained. Part 5: Disorders of the Bladder pays particular attention to problems of the bladder including bladder stones, urinary incontinence, urinary retention, interstitial cystitis, etc. Symptoms, diagnostic tests, and available treatments are discussed. Part 6: Genetic and Congenital Disorders that Affect the Kidneys offers information about the causes, symptoms, diagnosis, and treatment of various genetic and congenital disorders that affect the kidney such as Alport syndrome, Bartter syndrome, ectopic kidney, Fabry disease, medullary sponge kidney, and primary hyperoxaluria. Part 7: Cancers of the Kidneys and Urinary Tract describes the causes, symptoms, diagnosis, and treatment of various cancers that can affect the different components of the urinary system, including kidney cancer, bladder cancer, urethral cancer, and prostate cancer. Part 8: Kidney Failure: End-Stage Renal Disease explains treatments used to replace lost kidney function such as hemodialysis, peritoneal dialysis, and kidney transplantation. It talks about conservative management for kidney failure along with Medicare coverage available for dialysis and kidney transplant service. Information about end-of-life care for patients suffering from kidney disease is also provided. Part 9: Additional Help and Information offers a glossary of important terms and a directory of government and private organizations that provide help and information to patients with kidney disease and urinary tract disorders.


The Kidney in Genetic Disease

The Kidney in Genetic Disease
Author: Amin Y. Barakat
Publisher:
Total Pages: 384
Release: 1986
Genre: Medical
ISBN:

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Kidney and Urinary Tract Diseases and Disorders Sourcebook

Kidney and Urinary Tract Diseases and Disorders Sourcebook
Author: Linda Michelle Ross
Publisher: Omnigraphic, Incorporated
Total Pages: 0
Release: 1997
Genre: Health & Fitness
ISBN: 9780780800793

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"This volume of Omnigraphics' Health Reference Series addresses the concerns of those who live with kidney and urinary tract diseases and disorders, providing up-to-date research, diagnostic, and treatment information as well as demographic and statistical material, and strategies for controlling the spread of preventable conditions. Special nutritional and dietary guidelines for dialysis patients are also included."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved