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Influence of Gut Microbiota on Behavior and Its Disturbances

Influence of Gut Microbiota on Behavior and Its Disturbances
Author: Valentina Ignatova
Publisher:
Total Pages: 0
Release: 2020
Genre: Electronic books
ISBN:

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Hippocrates statement that ,ÄúAll disease begins in the gut,Äù continues to be up to date more than 2000¬†years later. Growing number of scientific reports focus on the important role of intestinal microorganisms for modulation of many systems and human behavior. As a key component of the gut brain, gut microbiota influences the development and maturation of the hypothalamic-pituitary-adrenal axis, affects the development and function of the immune system, regulates the blood-brain barrier, modulates the synthesis and recognition of neurotransmitters, regulates neurogenesis, formation of myelination and supports the development and function of the brain. Disruption of gut-brain axis function is associated with alterations in the stress response and might contribute to neuropsychiatric diseases as depression, autistic spectrum disorders, rapid eye movement sleep behavior disorder, Parkinson disease, Alzheimer disease and other mental conditions. Studies in animal models are crucial for guiding research on brain-gut-microbiome axis in humans, as the impact of microbiota on specific brain regions and aspects of animal behavior will help in the selection of tasks for cognitive assessment. Exploring the interaction of gut microbes and human brain will not only allow us to better understand the pathogenesis of neuropsychiatric disorders, but will also provide us new opportunities for the design of novel immuno- or microbe-based therapies.


Microbial Endocrinology

Microbial Endocrinology
Author: Mark Lyte
Publisher: Springer Science & Business Media
Total Pages: 325
Release: 2010-04-06
Genre: Medical
ISBN: 1441955763

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Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.


The Gut-Brain Axis

The Gut-Brain Axis
Author: Niall Hyland
Publisher: Academic Press
Total Pages: 512
Release: 2016-05-13
Genre: Medical
ISBN: 0128025441

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The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. Focuses on specific areas in which the microbiota has been implicated in gut-brain communication Examines common mechanisms and pathways by which the microbiota may influence brain and behavior Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior


Behavioral Neuroscience

Behavioral Neuroscience
Author: Sara Palermo
Publisher: BoD – Books on Demand
Total Pages: 162
Release: 2019-12-18
Genre: Science
ISBN: 1789840511

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What do we mean by "behavioral neuroscience?" This volume aims at providing an overview of behavioral neuroscience and deepening neuronal mechanisms and brain circuits that regulate the fundamental aspects of human behavior, such as cognitive and emotional functions. It is intended to give the reader the most up-to-date vision of how the interaction between biological mechanisms and neurocognitive processes leads to complex and highly organized behaviors.In recent years the strong impulse given to research on behavioral neuroscience has produced a large literature that documents the high level of complexity of the issue, for which it is necessary to provide a reasoned multidimensional analysis able to integrate the expertise of different disciplines.The book offers an excellent synopsis of perspectives, methods, empirical evidences, and international references. Therefore, it represents an extraordinary opportunity to target neuroscientific hot topics and to outline new horizons in the study of the relationship between brain and behavior.


Gut Microbiome and Behavior

Gut Microbiome and Behavior
Author:
Publisher: Academic Press
Total Pages: 434
Release: 2016-10-25
Genre: Science
ISBN: 0128039760

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Gut Microbiome and Behavior, the latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the gut microbiome on the brain and behavior, fully encapsulating the latest research in the field and defining the scope of this influence to outline potential mechanisms and possible implications. Contains the expertise of contributors in the field who discuss the gut microbiome and its effect on the brain and behavior Defines the scope of the influence of the gut microbiome and the potential mechanisms and implications Charts the way forward in this frontier area of research


Paying the Price

Paying the Price
Author: Paul McCrone
Publisher: King's Fund Publishing
Total Pages: 143
Release: 2008-01-01
Genre: Mental health services
ISBN: 9781857175714

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This report concludes that the prevalence of specific mental disorders is likely to remain broadly stable over the next 20 years. However, costs are projected to increase substantially, largely because of the expected increase in the number of people with dementia. The cost of lost employment is also projected to increase, confirming the major adverse economic impact of poor mental health. The report calls for future costs to be met, a focus on employment, more evidence-based interventions, better systems of early detection and treatment of dementia, and further research into the cost-effectiveness of a range of interventions, including mental health promotion and prevention initiatives.


Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease
Author: Mark Lyte
Publisher: Springer
Total Pages: 440
Release: 2014-07-05
Genre: Science
ISBN: 1493908979

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The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​


Microbes and the Mind

Microbes and the Mind
Author: C.S.M. Cowan
Publisher: Karger Medical and Scientific Publishers
Total Pages: 158
Release: 2021-05-06
Genre: Medical
ISBN: 331806856X

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Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.


Gut Microbiome in Neurological Health and Disorders

Gut Microbiome in Neurological Health and Disorders
Author: Amit Kumar Tripathi
Publisher: Springer Nature
Total Pages: 315
Release: 2022-08-03
Genre: Medical
ISBN: 9811945306

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This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.


Gut-brain Connection, Myth Or Reality?: Role Of The Microbiome In Health And Diseases

Gut-brain Connection, Myth Or Reality?: Role Of The Microbiome In Health And Diseases
Author: Adrien A Eshraghi
Publisher: World Scientific
Total Pages: 396
Release: 2021-11-03
Genre: Science
ISBN: 9811221162

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In this book the recent advancements in understanding the gut-brain interaction as well as gut microbiome and how this interaction plays a vital role in human health and disease are discussed. Each chapter gives an analysis of questions, research directions, and methods within the field of gut-brain axis. The readers will benefit from the latest knowledge about our understanding about how gut-brain axis and modulation of gut microbiome determines predisposition to neurological disorders. The multidisciplinary book is essential reading for anyone interested in the field of gut-brain axis and gut microbiome: from undergraduates to graduate students as well as scientists and physicians having an interest in the new exciting field of gut microbiome and its relationship with brain function.