Hydrophilic Interaction Chromatography PDF Download
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| Author | : Perry G. Wang |
| Publisher | : CRC Press |
| Total Pages | : 613 |
| Release | : 2011-02-17 |
| Genre | : Medical |
| ISBN | : 1439807531 |
Download Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications Book in PDF, ePub and Kindle
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.
| Author | : Waters Corporation |
| Publisher | : Waters Corporation |
| Total Pages | : 0 |
| Release | : 2014-04-21 |
| Genre | : Science |
| ISBN | : 9781879732087 |
Download Comprehensive Guide to HILIC Book in PDF, ePub and Kindle
The Comprehensive Guide to HILIC: Hydrophilic Interaction Chromatography, a 72-page book, illustrates how HILIC works and how separation scientists can improve their success in separating and quantifying polar compounds in a variety of sample matrices. Looking for something else? Learn a new technique or technology with the Waters Primers Series, view other titles available here: http://www.wiley.com/go/waters
| Author | : Bernard A. Olsen |
| Publisher | : John Wiley & Sons |
| Total Pages | : 336 |
| Release | : 2013-01-22 |
| Genre | : Science |
| ISBN | : 1118054172 |
Download Hydrophilic Interaction Chromatography Book in PDF, ePub and Kindle
Discover how to use HILIC to analyze and better understand polar compounds An increasingly popular analytical method, hydrophilic interaction chromatography (HILIC) has the ability to retain and separate polar compounds that are often difficult to analyze by reversed-phase high-performance liquid chromatography (HPLC) or other analytical methods. Offering a comprehensive review, this book enables readers to develop a fundamental understanding of how HILIC works and then apply that knowledge to develop and implement a variety of practical applications. Hydrophilic Interaction Chromatography begins with discussions of HILIC retention mechanisms, stationary phases, and general method development. This sets the foundation for the book's extensive coverage of applications. The authors address unique separation challenges for bioanalytical, environmental, pharmaceutical, and biochemical applications. Moreover, there is a thorough discussion of HILIC in two-dimensional chromatography. With contributions from leading analytical scientists who have extensive experience in HILIC as well as HPLC, Hydrophilic Interaction Chromatography serves as a practical guide for researchers, featuring: Detailed examples of HILIC methods and development approaches Thorough explanations of retention mechanisms and the impact of stationary phase and mobile phase properties on separations Step-by-step guidance for developing efficient, sensitive, and robust HILIC methods References to the primary literature at the end of each chapter Hydrophilic Interaction Chromatography is written for scientists who use or develop analytical methods for the separation of polar compounds. In particular, these researchers will discover how HILIC can be used to analyze and better understand the composition of pharmaceutical, bioanalytical, biochemical, chemical, food, and environmental samples.
| Author | : Stavros Kromidas |
| Publisher | : John Wiley & Sons |
| Total Pages | : 248 |
| Release | : 2019-04-04 |
| Genre | : Science |
| ISBN | : 3527812776 |
Download Gradient HPLC for Practitioners Book in PDF, ePub and Kindle
This practical guide for analytical scientists explains the use of gradients in liquid chromatography. The fundamentals of gradient separations, as well as the most common application scenarios are addressed, from LC-MS coupling to biochromatography to the separation of ionic substances. Throughout, this handy volume provides detailed hands-on information for practitioners, enabling them to use gradient separation methods reliably and efficiently.
| Author | : Ziad El Rassi |
| Publisher | : Elsevier |
| Total Pages | : 956 |
| Release | : 2021-08-15 |
| Genre | : Science |
| ISBN | : 0128245123 |
Download Carbohydrate Analysis by Modern Liquid Phase Separation Techniques Book in PDF, ePub and Kindle
Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques. Covers the basic principles of modern liquid phase separation techniques, along with their applications Compiles up-to-date information on the field of carbohydrate analysis, along with updates on separation science Focuses on problems currently faced in carbohydrate analysis and the solutions necessary for further progress
| Author | : Klara Valko |
| Publisher | : Elsevier |
| Total Pages | : 613 |
| Release | : 2000-10-13 |
| Genre | : Science |
| ISBN | : 0080541097 |
Download Separation Methods in Drug Synthesis and Purification Book in PDF, ePub and Kindle
Separation Methods in Drug Synthesis and Purification
| Author | : Stavros Kromidas |
| Publisher | : John Wiley & Sons |
| Total Pages | : 418 |
| Release | : 2021-11-08 |
| Genre | : Science |
| ISBN | : 3527347895 |
Download Optimization in HPLC Book in PDF, ePub and Kindle
Learn to maximize the performance of your HPLC or UHPLC system with this resource from leading experts in the field Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes, this comprehensive guide leaves few questions unanswered. Readers will also benefit from the inclusion of: A thorough introduction to optimization strategies for different modes and uses of HPLC, including working under regulatory constraints An exploration of computer aided HPLC optimization, including ChromSwordAuto and Fusion QbD A treatment of current challenges for HPLC users in industry as well as large and small analytical service providers Discussions of current challenges for HPLC equipment suppliers Tailor-made for analytical chemists, chromatographers, pharmacologists, toxicologists, and lab technicians, Optimization in HPLC: Concepts and Strategies will also earn a place on the shelves of analytical laboratories in academia and industry who seek a one-stop reference for optimizing the performance of HPLC systems.
| Author | : Gregory K. Webster |
| Publisher | : CRC Press |
| Total Pages | : 567 |
| Release | : 2019-10-28 |
| Genre | : Medical |
| ISBN | : 042951039X |
Download Chromatographic Methods Development Book in PDF, ePub and Kindle
This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics, and vendors in the field. This book is an inclusive guide to developing all chromatographic methods (such as liquid chromatography and gas chromatography). It covers modern techniques for developing methods using chromatographic development software, requirements for validations, discussion on orthogonality, and how to transfer methods from HPLC to UHPLC. The text introduces some newer techniques that are heavily employed by chemists analyzing proteins and RNAi, as well as novel techniques such as counter current chromatography. This book is valuable for both the novice starting out in undergraduate labs and those who are new to the pharmaceutical industry and is a useful reference for seasoned analysts.
| Author | : A. Cavazzini |
| Publisher | : Elsevier Inc. Chapters |
| Total Pages | : 26 |
| Release | : 2013-01-08 |
| Genre | : Science |
| ISBN | : 012807132X |
Download Liquid Chromatography Book in PDF, ePub and Kindle
Hydrophilic interaction liquid chromatography (HILIC) has become in the last years a leading technique for the separation of small and large polar molecules. This chapter begins with a discussion about the most relevant characteristics of HILIC mode that makes it a complementary and, in some cases, alternative technique to the more traditional reversed- and normal-phase modes. Subsequently, the fundamentals of retention mechanisms in HILIC are revised in light of the most recent findings in the field. The chapter ends with an overview of the materials used as stationary and mobile phases in HILIC and of the applications of this analytical technique in different branches of science.
| Author | : Yuri V. Kazakevich |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1136 |
| Release | : 2007-02-16 |
| Genre | : Science |
| ISBN | : 0470087943 |
Download HPLC for Pharmaceutical Scientists Book in PDF, ePub and Kindle
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
