Host Defense Peptides And Their Potential As Therapeutic Agents PDF Download
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| Author | : Richard M. Epand |
| Publisher | : Springer |
| Total Pages | : 323 |
| Release | : 2016-05-06 |
| Genre | : Science |
| ISBN | : 3319329499 |
Download Host Defense Peptides and Their Potential as Therapeutic Agents Book in PDF, ePub and Kindle
This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimicrobial and anticancer host defense peptides. The authors provide new insights into their mechanisms of action and their immunomodulatory properties, and review recent advances in the design of novel therapeutic molecules. Lastly, their potential to prevent preterm births and Staphylococcus aureus infections is highlighted. The book is of interest to researchers, industry and clinicians alike.
| Author | : Alden Aubert |
| Publisher | : Createspace Independent Publishing Platform |
| Total Pages | : 324 |
| Release | : 2017-05-22 |
| Genre | : |
| ISBN | : 9781974385874 |
Download Host Defense Peptides and Their Potential As Therapeutic Agents Book in PDF, ePub and Kindle
This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimicrobial and anticancer host defense peptides. The authors provide new insights into their mechanisms of action and their immunomodulatory properties, and review recent advances in the design of novel therapeutic molecules. Lastly, their potential to prevent preterm births and Staphylococcus aureus infections is highlighted. The book is of interest to researchers, industry and clinicians alike.
| Author | : Deirdre A. Devine |
| Publisher | : Cambridge University Press |
| Total Pages | : 416 |
| Release | : 2004-09-20 |
| Genre | : Medical |
| ISBN | : 9780521822206 |
Download Mammalian Host Defense Peptides Book in PDF, ePub and Kindle
Cationic antimicrobial peptides are multifunctional peptides of the innate immune system, which not only act directly against microorganisms, but also signal between early and late immune responses and modulate inflammatory reposnes. The significance of these host defence peptides in combating infection and in host-microbe homeostasis has become increasingly clear, through advances made by microbiologists, biochemists, biophysicists, immunologists, molecular biologists, and a range of medical and pharmaceutical researchers. This book, drawing together contributions from leading scientists, reviews significant recent advances in our knowledge of mammalian antimicrobial peptides. In addition to providing up-to-date overviews of their structure, expression and biology, their multiple activities and interactions with microbial populations as well as their potential application as novel therapeutic agents are summarized. Chapters describing developments using animal models and investigations of the roles of these host defence peptides in microbial infections are complemented by chapters addressing their mechanisms of action and of microbial resistance.
| Author | : Guangshun Wang |
| Publisher | : CABI |
| Total Pages | : 288 |
| Release | : 2017-09-01 |
| Genre | : Medical |
| ISBN | : 1786390396 |
Download Antimicrobial Peptides Book in PDF, ePub and Kindle
Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide. Harnessing and creating AMPs synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. This new edition lays the foundations for studying AMPs, including a discovery timeline, terminology, nomenclature and classifications. It covers current advances in AMP research and examines state-of-the-art technologies such as bioinformatics, combinatorial libraries, high-throughput screening, database-guided identification, genomics and proteomics-based prediction, and structure-based design of AMPs. Thoroughly updated and revised, this second edition contains new content covering: defensins; cathelicidins; anti-MRSA, antifungal, antiviral, anticancer and antibiofilm strategies; combined treatments; adjuvants in vaccines; advances in AMP technologies that cover surface coating to prevent biofilm formation; nanofiber encapsulation technologies for delivery and sustained release; and understanding innate immunity and the basis for immune boosting to overcome obstacles in developing AMPs into therapeutic agents. Written and reviewed by a group of established investigators in the field, Antimicrobial Peptides is a valuable resource for postgraduate students, researchers, educators, and medical and industrial personnel.
| Author | : Mark Hulett |
| Publisher | : Frontiers Media SA |
| Total Pages | : 399 |
| Release | : 2021-04-07 |
| Genre | : Medical |
| ISBN | : 2889666670 |
Download Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond Book in PDF, ePub and Kindle
| Author | : Luis Enjuanes |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 261 |
| Release | : 2005-10-25 |
| Genre | : Medical |
| ISBN | : 3540267654 |
Download Coronavirus Replication and Reverse Genetics Book in PDF, ePub and Kindle
Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 102 |
| Release | : 2006-01-03 |
| Genre | : Medical |
| ISBN | : 0309180686 |
Download Treating Infectious Diseases in a Microbial World Book in PDF, ePub and Kindle
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
| Author | : Gopinath Kasetty |
| Publisher | : |
| Total Pages | : 54 |
| Release | : 2014 |
| Genre | : |
| ISBN | : 9789187651380 |
Download Host Defense Peptides of the Coagulation System and Their Therapeutic Potential Book in PDF, ePub and Kindle
| Author | : Katsumi Matsuzaki |
| Publisher | : Springer |
| Total Pages | : 304 |
| Release | : 2019-04-12 |
| Genre | : Medical |
| ISBN | : 9811335885 |
Download Antimicrobial Peptides Book in PDF, ePub and Kindle
This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.
| Author | : David A. Phoenix |
| Publisher | : John Wiley & Sons |
| Total Pages | : 354 |
| Release | : 2012-12-27 |
| Genre | : Science |
| ISBN | : 3527652876 |
Download Antimicrobial Peptides Book in PDF, ePub and Kindle
In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.
