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Handbook of Safety Assessment of Nanomaterials

Handbook of Safety Assessment of Nanomaterials
Author: Bengt Fadeel
Publisher: CRC Press
Total Pages: 565
Release: 2014-12-10
Genre: Medical
ISBN: 9814463361

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The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.


Handbook of Nanosafety

Handbook of Nanosafety
Author: Ulla Vogel
Publisher: Elsevier
Total Pages: 377
Release: 2013-12-17
Genre: Science
ISBN: 0124166628

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Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment. Multi-authored book, written by leading researchers in the field of nanotoxicology and nanosafety Features state-of-the-art physical and chemical characterization of engineered nanomaterials (ENM) Develops strategies for exposure assessment, risk assessment and risk management Includes practical case studies and exposure scenarios to demonstrate how you can safely use ENM in the workplace


Handbook of Functionalized Nanomaterials

Handbook of Functionalized Nanomaterials
Author: Chaudhery Mustansar Hussain
Publisher: Elsevier
Total Pages: 406
Release: 2021-08-23
Genre: Technology & Engineering
ISBN: 0128224355

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Handbook of Functionalized Nanomaterials: Environmental Health and Safety discusses the reactive properties of FNMs used in a range of applications, and their toxic impact on the environment. Nanomaterials have unique properties that can make them highly reactive. This reactivity can cause unwanted interactions with living cells, an increase in oxidative stress or damage to genetic material - resulting in damage to the environment and local wildlife. This negative impact is often further increased after surface functionalization of nanomaterials with other materials which offer unique properties of their own. To ensure environmental safety and ecological balance, rigorous toxicity testing of functionalized nanomaterials (FNMs) is necessary. This book discusses the toxicological uncertainties of FNMs and the limitations of FNMs in a range of applications. Later chapters propose methods to reliably assess the harm that functionalized nanomaterials can cause to the environment and wildlife, as well covering recent developments in the field of environmental health safety. The book concludes with a discussion on the future prospects of safe functionalized nanomaterials. Offers a novel, integrated approach, bridging the gap between FNMs and environmental health and safety Analyses the reactive properties of FNMs and their toxicological potential Provides an in-depth look at the impact of functionalized nanomaterials on the environment


The ELSI Handbook of Nanotechnology

The ELSI Handbook of Nanotechnology
Author: Chaudhery Mustansar Hussain
Publisher: John Wiley & Sons
Total Pages: 480
Release: 2020-03-17
Genre: Technology & Engineering
ISBN: 1119593018

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This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.


Nanomaterials

Nanomaterials
Author: Igor Linkov
Publisher: Springer Science & Business Media
Total Pages: 459
Release: 2008-12-26
Genre: Technology & Engineering
ISBN: 1402094914

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Many potential questions regarding the risks associated with the development and use of wide-ranging technologies enabled through engineered nanomaterials. For example, with over 600 consumer products available globally, what information exists that describes their risk to human health and the environment? What en- neering or use controls can be deployed to minimize the potential environmental health and safety impacts of nanomaterials throughout the manufacturing and product lifecycles? How can the potential environmental and health benefits of nanotechnology be realized and maximized? The idea for this book was conceived at the NATO Advanced Research Workshop (ARW) on “Nanomaterials: Environmental Risks and Benefits and Emerging Consumer Products. ” This meeting – held in Algarve, Portugal, in April 2008 – started with building a foundation to harmonize risks and benefits associated with nanomaterials to develop risk management approaches and policies. More than 70 experts, from 19 countries, in the fields of risk assessment, decision-analysis, and security discussed the current state-of-knowledge with regard to nanomaterial risk and benefits. The discussion focused on the adequacy of available risk assessment tools to guide nanomaterial applications in industry and risk governance. The workshop had five primary purposes: Describe the potential benefits of nanotechnology enabled commercial products. Identify and describe what is known about environmental and human health risks of nanomaterials and approaches to assess their safety. Assess the suitability of multicriteria decision analysis for reconciling the benefits and risks of nanotechnology.


Handbook of Nanomaterials for Manufacturing Applications

Handbook of Nanomaterials for Manufacturing Applications
Author: Chaudhery Mustansar Hussain
Publisher: Elsevier
Total Pages: 526
Release: 2020-04-12
Genre: Technology & Engineering
ISBN: 0128213825

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Handbook of Nanomaterials for Manufacturing Applications covers the challenges and obstacles involved in using nanomaterials in manufacturing. In particular, the lack of information, the possibility of adverse impacts on the environment, human health, safety and sustainability and other remaining challenges. This book addresses these challenges for the use of nanomaterials in major manufacturing sectors and suggests how they may be overcome. It was written to summarize, in a one-stop, concise manner, how nanomaterials and nanotechnology are being used to enhance current manufacturing techniques and processes in order to create more sustainable products in a range of industry sectors. This book will be of great use to materials scientists and engineers who are looking to gain a greater understanding on how nanotechnology is being used to improve the products we use in our daily lives. Demonstrates how cutting-edge developments in nanomaterials are being used to make more efficient manufacturing processes in a range of industry sectors Explores how using nanomaterials can help engineers create innovative consumer products Discusses the legal, economic and toxicity issues arising from using nanomaterials in manufacturing processes


Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer

Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer
Author: Saravanan, Muthupandian
Publisher: IGI Global
Total Pages: 559
Release: 2021-02-12
Genre: Medical
ISBN: 1799850501

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Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.


Health and Environmental Safety of Nanomaterials

Health and Environmental Safety of Nanomaterials
Author: James Njuguna
Publisher: Elsevier
Total Pages: 345
Release: 2014-02-15
Genre: Technology & Engineering
ISBN: 0857096672

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Health and Environmental Safety of Nanomaterials addresses concerns about the impact of nanomaterials on the environment and human health, and examines the safety of specific nanomaterials. Understanding the unique chemical and physical properties of nanostructures has led to many developments in the applications of nanocomposite materials. While these materials have applications in a huge range of areas, their potential for toxicity must be thoroughly understood. Part one introduces the properties of nanomaterials, nanofillers, and nanocomposites, and questions whether they are more toxic than their bulk counterparts. Part two looks at the release and exposure of nanomaterials. The text covers sampling techniques and data analysis methods used to assess nanoparticle exposure, as well as protocols for testing the safety of polymer nanocomposites. It explains characterization techniques of airborne nanoparticles and life cycle assessment of engineered nanomaterials. Part three focuses on the safety of certain nanomaterials, including nanolayered silicates, carbon nanotubes, and metal oxides. In particular, it explores the potential ecotoxicological hazards associated with the different structures of carbon nanotubes and the safe recycling of inorganic and carbon nanoparticles. The final two chapters address the risks of nanomaterials in fire conditions: their thermal degradation, flammability, and toxicity in different fire scenarios. This is a scientific guide with technical background for professionals using nanomaterials in industry, scientists, academicians, research scholars, and polymer engineers. It also offers a deep understanding of the subject for undergraduate and postgraduate students. Introduces the properties of nanomaterials, nanofillers, and nanocomposites, and questions whether they are more toxic than their bulk counterparts Covers sampling techniques and data analysis methods used to assess nanoparticle exposure, as well as protocols for testing the safety of polymer nanocomposites Explores the potential ecotoxicological hazards associated with the different structures of carbon nanotubes and the safe recycling of inorganic and carbon nanoparticles


Adverse Effects of Engineered Nanomaterials

Adverse Effects of Engineered Nanomaterials
Author: Bengt Fadeel
Publisher: Academic Press
Total Pages: 367
Release: 2012-01-27
Genre: Medical
ISBN: 0123869404

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An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety.


Nanomaterials

Nanomaterials
Author: Marcelo Larramendy
Publisher: BoD – Books on Demand
Total Pages: 224
Release: 2015-07-15
Genre: Science
ISBN: 953512143X

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This edited book, Nanomaterials - Toxicity and Risk Assessment, is a collection of current research and information on numerous advances on the toxicity and hazardous effects of nanomaterials, including theoretical and experimental approaches as well as nanotechnology applications in the field of medicine, pharmacology, and the manufacture of nanoscale materials. Based on the large number of nanomaterial applications, a careful understanding of the associated systemic and local toxicity is critically required.