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Handbook of Membrane Channels

Handbook of Membrane Channels
Author:
Publisher: Academic Press
Total Pages: 615
Release: 2012-12-02
Genre: Science
ISBN: 032313890X

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This handbook provides a thorough account of recent directions in membrane channel research. Each subject is covered in terms of channel biophysics, pharmacology, and molecular biology. The introductory chapter reviews methodologies of molecular biology currently used for studying molecular structure and function of membrane channels and specific domains in channel proteins.


Handbook of Ion Channels

Handbook of Ion Channels
Author: Jie Zheng
Publisher: CRC Press
Total Pages: 682
Release: 2015-02-25
Genre: Medical
ISBN: 1466551429

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The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce


Channels, Carriers, and Pumps

Channels, Carriers, and Pumps
Author: Wilfred D. Stein
Publisher: Elsevier
Total Pages: 423
Release: 2014-12-09
Genre: Science
ISBN: 0124165834

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An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building


Ion Channels

Ion Channels
Author: Nikita Gamper
Publisher: Humana Press
Total Pages: 456
Release: 2016-05-01
Genre: Science
ISBN: 9781493960095

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This Methods in Molecular Biology book offers strategies and protocols for studying a large group of proteins that form ionic channels in the plasma membrane and intracellular membranes of cells. Includes step-by-step protocols, materials lists, tips and more."


Handbook of Receptors and Channels

Handbook of Receptors and Channels
Author: R. Alan North
Publisher: CRC Press
Total Pages: 372
Release: 1994-10-25
Genre: Science
ISBN: 9780849383229

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This authoritative and comprehensive volume presents a perspective in the molecular and cellular diversity of membrane ion channels. Written in an accessible format, it depicts the structure and function of each of the known classes of ion channels. Each chapter provides amino acid sequences, including data base accession numbers; views of secondary, tertiary and quaternary channel structure; and evolutionary relationships among channels.


Membrane Handbook

Membrane Handbook
Author: Winston Ho
Publisher: Springer Science & Business Media
Total Pages: 957
Release: 2012-12-06
Genre: Science
ISBN: 1461535484

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Membrane processes have wide industrial ap This handbook reviews the published litera plications covering many existing and emerging ture, presents an in-depth description of com uses in the chemical, petrochemical, petroleum, mercialized membrane processes, and gives a state-of-the-art review of new membrane pro environmental, water treatment, pharmaceutic al, medical, food, dairy, beverage, paper, tex cess concepts under development. It is intended tile, and electronic industries. The existing ap to be a single source of underlying principles, membranes, membrane modules, process de plications include: (1) dialysis for the purifica tion of human blood (the artificial kidney), (2) sign, applications, and cost estimates. It is also electrodialysis for the desalination of brackish a first attempt to bridge the gap between the water to produce potable water, (3) reverse theory and practice. osmosis for the desalination of seawater, (4) There are several groups which may benefit ultrafiltration for the concentration of large pro from this handbook. It can be used as educa tein molecules from cheese, casein whey, and tional material for industrial personnel engaged milk, and (5) microfiltration for the sterilization in membrane separations. For scientists and of pharmaceutical and medical products, beer, engineers active in research and development in wine, and soft drinks. Since membrane pro synthetic membranes, it will serve as a single cesses generally have low capital investment, as source of reference for the entire field.


Ion Channels

Ion Channels
Author: David J. Aidley
Publisher: Cambridge University Press
Total Pages: 324
Release: 1996-08-13
Genre: Medical
ISBN: 9780521498821

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Ion channels are crucial components of living cells. Situated in the cell's membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly.


Membranes, Channels, and Noise

Membranes, Channels, and Noise
Author: Robert S. Eisenberg
Publisher: Springer Science & Business Media
Total Pages: 292
Release: 2012-12-06
Genre: Science
ISBN: 1468448501

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This volume is a collection of papers designed to increase awareness and utilization of fluctuation theory for the description of ionic events at the membrane. The papers are revised and updated versions of presentations made at a workshop entitled "Noise Measurements as a Probe of Ionic Conductance. " As a result of discussions held at that meeting, the participants were asked to provide selected chapters designed to provide detailed descriptions of the theory and its application to a number of membrane channels. Fluctuation theory was developed initially to explain statistical fluctuations of ordinary physical quantities such as random collisions between gas molecules and walls. As knowledge of ionic pores has advanced, it has become apparent that randomized fluctuations could be utilized to characterize pore behavior in excitable and epithelial membranes. Because of the increased awareness of the applicability of fluctuation theory, the workshop participants were invited to contribute papers to this volume to provide them with an opportunity to teach others the essentials of noise measurements. The emphasis of this volume is on the practical steps which must be followed to make and interpret measurements of noise, both noise produced by natural fluctuatjons of the transport system, and noise which is the response to an applied stochastic signal. This collection of papers is meant to emphasize practical limitations as well as practical and theoretical advantages of such measurements.


Ionic Channels of Excitable Membranes

Ionic Channels of Excitable Membranes
Author: Bertil Hille
Publisher: Sinauer Associates, Incorporated
Total Pages: 638
Release: 1992
Genre: Medical
ISBN:

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This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.


Channels, Carriers, and Pumps

Channels, Carriers, and Pumps
Author: Wilfred D. Stein
Publisher: Elsevier
Total Pages: 341
Release: 2012-12-02
Genre: Science
ISBN: 0323138152

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For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport kinetics, function, and regulation. Experimental data are linked with theory. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building