Guide To Signal Pathways In Immune Cells PDF Download
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Author | : E. Nigel Wardle |
Publisher | : Springer Science & Business Media |
Total Pages | : 425 |
Release | : 2009-04-21 |
Genre | : Medical |
ISBN | : 160327538X |
Download Guide to Signal Pathways in Immune Cells Book in PDF, ePub and Kindle
To read current biomedical science, one has to have a working knowledge of how important effector molecules cause transduction of their signal within cells, altering the control of genes. This work aims to provide that basic knowledge for medical readers. Students of immunology or cell biology will note its relevance. One will learn how platelets, macrophages, neutrophils, T and B lymphocytes and natural killer cells perform their functions and how skin, breast, prostate and colon cancers emerge. The associated diagrams and tables are used to obviate extensive text. Appropriate references to articles and reviews by workers in each field are given so that further consideration can easily be undertaken. We are all at differing stages of our appreciation of immunology and of pat- physiology. Some persons will have a profound background in biochemistry or molecular biology. Others will have a reminiscence of lectures received years ago. Since this work is principally for clinical doctors, the sections that can be avoided at first reading are marked with an asterisk (*). Always proceed line by line and think of associations that you know. Do you feel comfortable with the statement, “Interleukin 6 stimulates glucose uptake in renal proximal tubular cells, and that action is associated with Stat3, PI3K/Akt, MAPKs and NF-kB signal pathways”? If not, please read on.
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Release | : 2009 |
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Download Guide to Signal Pathways in Immune Cells Book in PDF, ePub and Kindle
Author | : Kenneth Murphy |
Publisher | : Garland Science |
Total Pages | : |
Release | : 2010-06-22 |
Genre | : Medical |
ISBN | : 9780815344575 |
Download Janeway's Immunobiology Book in PDF, ePub and Kindle
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author | : Isabelle Couillin |
Publisher | : Springer Science & Business Media |
Total Pages | : 233 |
Release | : 2011-07-02 |
Genre | : Medical |
ISBN | : 3034801483 |
Download The Inflammasomes Book in PDF, ePub and Kindle
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Download Molecular Biology of The Cell Book in PDF, ePub and Kindle
Author | : David A. Frank |
Publisher | : Springer Science & Business Media |
Total Pages | : 358 |
Release | : 2002-12-31 |
Genre | : Medical |
ISBN | : 1402073402 |
Download Signal Transduction in Cancer Book in PDF, ePub and Kindle
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Author | : Miyuki Azuma |
Publisher | : Springer Nature |
Total Pages | : 326 |
Release | : 2019-11-22 |
Genre | : Medical |
ISBN | : 9813297174 |
Download Co-signal Molecules in T Cell Activation Book in PDF, ePub and Kindle
This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.
Author | : Lewis C. Cantley |
Publisher | : |
Total Pages | : 452 |
Release | : 2014-05-31 |
Genre | : Science |
ISBN | : 9780879699017 |
Download Signal Transduction Book in PDF, ePub and Kindle
"This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--
Author | : Ernst J. M. Helmreich |
Publisher | : Oxford University Press, USA |
Total Pages | : 372 |
Release | : 2001 |
Genre | : Language Arts & Disciplines |
ISBN | : 9780198508205 |
Download The Biochemistry of Cell Signalling Book in PDF, ePub and Kindle
A comprehensive study of the principles of cell signalling, concentrating on the structural and mechanistic aspects. The book is divided into four parts describing the machinery of signal transduction, the implementation of the signalling cascades focussing on the effect on gene transcription, the globular cellular regulatory programs, and the loss of regulatory control and its consequences with repsect to the molecular basis of cancer. There are well over 200 figures, many in 3-D representations.
Author | : Martin Powell |
Publisher | : eBook Partnership |
Total Pages | : 259 |
Release | : 2015-01-22 |
Genre | : |
ISBN | : 0956689833 |
Download Medicinal Mushrooms - A Clinical Guide Book in PDF, ePub and Kindle
Updated and expanded second edition of the leading reference book on the clinical use of medicinal mushrooms. Written by a biochemist and herbalist with over 20 years' experience of working with medicinal mushrooms, this book provides an in-depth resource for healthcare practitioners. It covers 20 of the most widely used species and contains sections on their use for cancer and other health conditions, as well as discussion of the different formats of mushroom supplement available . 'This really important book is a unique and excellent compilation.' Dr SP Wasser - Editor, International Journal of Medicinal Mushrooms 'This beautifully illustrated book is an invaluable resource on medicinal mushrooms.' Giovanni Maciocia - Author, Foundations of Chinese Medicine 'Easily the most accessible primer on the pharmacology, applications and Chinese medical uses of the top mycological medicinals.' Journal of Chinese Medicine