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| Author | : Nora Y. K. Chew |
| Publisher | : |
| Total Pages | : 378 |
| Release | : 2000 |
| Genre | : Aerosol therapy |
| ISBN | : |
| Author | : Anthony J. Hickey |
| Publisher | : CRC Press |
| Total Pages | : 628 |
| Release | : 2003-09-03 |
| Genre | : Medical |
| ISBN | : 0824756649 |
This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.
| Author | : Anne Haaije de Boer |
| Publisher | : |
| Total Pages | : |
| Release | : 2005 |
| Genre | : |
| ISBN | : 9789036722681 |
| Author | : Brian H. Kaye |
| Publisher | : John Wiley & Sons |
| Total Pages | : 323 |
| Release | : 2008-07-11 |
| Genre | : Science |
| ISBN | : 3527614036 |
Characterization of fine particles is a difficult task! A large number of industries deal with materials in powder form. The properties of these powders depend on their particle size, particle shape and size distributions, surface and porosity. What are the methods? What are the problems? What questions need answering? This new book covers the problems of sampling both powders and aerosols, and discusses calibration standards for different instruments. It takes into account fractionating methods for fine particles, e.g., sieving procedures, sedimentation methods, and the use of cyclones. Image analysis and its use for the measurement of the size and shape of powder grains and light-diffraction techniques for size evaluation are presented. Furthermore, this books covers the most effective methods for measuring surface areas, fractal structures of rough surfaces, and pore structures of porous bodies. Practitioners will find tips for modification of analytical procedures for on-line characterization, and many graphs for comparing data obtained by different methods are presented.
| Author | : Xian Ming Zeng |
| Publisher | : CRC Press |
| Total Pages | : 264 |
| Release | : 2000-10-26 |
| Genre | : Medical |
| ISBN | : 1135729778 |
Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It review some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).
| Author | : Teerapol Srichana |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2017 |
| Genre | : Inhalers |
| ISBN | : 9781536106411 |
This book is a compilation of most works published during 2000-2016 in the area of dry powder inhalers, especially related to the issues with formulation and device design. The dry powder inhalers aim to deliver the medication to the respiratory airways. It is suitable for postgraduate students and researchers who work in the areas of dry powder inhalers. It provides some background knowledge in size characterization, flow properties, forces, and interaction of air and particles. It also ends with in vitro quality control of dry powder inhalers. This book was finished in Hawaii where the author spent his time during April 2016. Thank you to Prince of Songkla University for the financial support. The author had to work very hard for one month without a holiday. Thank you to Professor Aran Pattanothai for overseeing this work to make sure that the researchers were on schedule all the time. Thanks to the authors staff at the Graduate School, Prince of Songkla University who had to work hard and be patient when the author was not in the office. Thanks to the authors wife and son who had to wait for him at home in Thailand. Thanks to Dr Tan Suwandecha and Dr Janwit Dechraksa for their great efforts in copy editing and compiling all the references. The author also thanks Dr Somchai Sawatdee and Dr Dhamodharan Bakkiyaraj for their comments, and Dr Padmavathi Alwar Ramanujam for her proofreading. The greatest help was from Professor Alan Coombes, Professor Pornanong Aramwit, and Dr Brian Hodgeson for their criticisms and comments to make this book readable.
| Author | : Harry G. Brittain |
| Publisher | : CRC Press |
| Total Pages | : 440 |
| Release | : 1995-07-19 |
| Genre | : Medical |
| ISBN | : 9780824793722 |
This unique reference provides the first systematic coverage available in a single-source volume on the application of materials science techniques to the pharmaceutical field-offering a comprehensive program for the physical characterization of raw materials, drug substances, and formulated products.
| Author | : M. Geraldine Venthoye |
| Publisher | : |
| Total Pages | : |
| Release | : 1997 |
| Genre | : |
| ISBN | : |
| Author | : Anthony J. Hickey |
| Publisher | : CRC Press |
| Total Pages | : 548 |
| Release | : 1996-06-07 |
| Genre | : Medical |
| ISBN | : 9781420002256 |
This unique reference integrates the theory and practical use of aerosols in inhalation therapy into a single resource-presenting the physical chemistry of formulation, the physics of aerosol generation, aerodynamic behavior, and therapeutic implications. Offers up-to-date techniques for droplet and particle generation, including air-blast and ultrasonic nebulizers, propellant-driven metered-dose inhalers, dry-powder inhalers, and elecctrospray systems!
| Author | : Warren H. Finlay |
| Publisher | : Academic Press |
| Total Pages | : 328 |
| Release | : 2001-07-06 |
| Genre | : Medical |
| ISBN | : 9780122569715 |
The Mechanics of Inhaled Pharmaceutical Aerosols, An Introduction provides a unique and comprehensive treatment of the mechanics of inhaled pharmaceutical aerosols. The book covers a wide range of topics and many new perspectives are given by drawing on research from a variety of fields. Novel, in-depth expositions of the most common delivery devices are given, including nebulizers, dry powder inhalers and propellant metered dose inhalers. The behaviour of aerosols in the respiratory tract is explained in detail, with complete coverage of the fundamentals of current deposition models. The book begins by providing a comprehensive introduction to aspects of aerosol mechanics that are relevant to inhaled pharmaceutical aerosols. It then gives an exhaustive pedagogical description of the behaviour of evaporating and condensing droplets (both aqueous and propellant-based), an introductory chapter on lung geometry and inhalation patterns, and coverage of relevant aspects of fluid mechanics in the lung. Finally, the book provides invaluable, detailed coverage on the mechanics of common pharmaceutical aerosol delivery systems and deposition in the respiratory tract. Throughout the book are many detailed numerical examples that apply the salient concepts to typical inhaled pharmaceutical aerosols. This book will be of interest to scientists and engineers involved in the research and development of inhaled pharmaceutical aerosol products. Experienced practitioners will find many new perspectives that will greatly enhance their understanding of this complex and rapidly growing field. For those delivering therapeutic agents to the lung, this book is a must-have. Students and academics will find this book an invaluable tool and for newcomers it is a worthy guide to the diverse fields that must be understood to work in the area of inhaled pharmaceutical aerosols.
