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| Author | : Gautam B. Singh |
| Publisher | : Springer |
| Total Pages | : 345 |
| Release | : 2014-09-24 |
| Genre | : Technology & Engineering |
| ISBN | : 3319114034 |
Download Fundamentals of Bioinformatics and Computational Biology Book in PDF, ePub and Kindle
This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolboxTM. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.
| Author | : Basant K. Tiwary |
| Publisher | : Springer Nature |
| Total Pages | : 239 |
| Release | : 2021-11-23 |
| Genre | : Medical |
| ISBN | : 9811642419 |
Download Bioinformatics and Computational Biology Book in PDF, ePub and Kindle
This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences.
| Author | : Dan E. Krane |
| Publisher | : |
| Total Pages | : 314 |
| Release | : 2003 |
| Genre | : Bioinformatics |
| ISBN | : 9780321190222 |
Download Fundamental Concepts of Bioinformatics Book in PDF, ePub and Kindle
Co-authored by a biologist and computer scientist, this book is designed to make bioinformatics useful to undergraduates and prepare them for more advanced work. It covers problems at the end of each chapter, which use real data to help students apply what they have learned from both a statistical and biological point of view.
| Author | : S. Harisha |
| Publisher | : I. K. International Pvt Ltd |
| Total Pages | : 266 |
| Release | : 2013-12-30 |
| Genre | : Bioinformatics |
| ISBN | : 8189866419 |
Download Fundamentals of Bioinformatics Book in PDF, ePub and Kindle
Bioinformatics is an upcoming discipline of Life Sciences. It is an integration of computer science, and mathematical and statistical methods to manage and analyze the biological data. The fundamental issues that directly impact an understanding of life at structural, functional and molecular level, and regulation of gene expression can be studied by using bioinformatics tools. The Fundamentals of Bioinformatics is a comprehensive book for undergraduates, postgraduates and research scholars, who urge to learn about theoretical as well as practical aspects of this upcoming field. This pioneering book provides up-to-date information on bioinformatics and emphasizes recent topics like drug design technology, pharmacogenomics, proteomics and genomics. The present textbook will be an asset to Life sciences and technology institutions, since it has been designed based on the prescribed syllabus of various Indian Universities and aboard, and cover all the important topics on Bioinformatics.
| Author | : Rui Jiang |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 412 |
| Release | : 2013-11-26 |
| Genre | : Computers |
| ISBN | : 3642389511 |
Download Basics of Bioinformatics Book in PDF, ePub and Kindle
This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate Statistical Methods in Bioinformatics Research, Association Analysis for Human Diseases: Methods and Examples, Data Mining and Knowledge Discovery Methods with Case Examples, Applied Bioinformatics Tools, Foundations for the Study of Structure and Function of Proteins, Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine, and Advanced Topics in Bioinformatics and Computational Biology. This book can serve as not only a primer for beginners in bioinformatics, but also a highly summarized yet systematic reference book for researchers in this field. Rui Jiang and Xuegong Zhang are both professors at the Department of Automation, Tsinghua University, China. Professor Michael Q. Zhang works at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
| Author | : Stephen Krawetz |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 623 |
| Release | : 2008-12-11 |
| Genre | : Science |
| ISBN | : 1597454400 |
Download Bioinformatics for Systems Biology Book in PDF, ePub and Kindle
Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.
| Author | : Richard Durbin |
| Publisher | : Cambridge University Press |
| Total Pages | : 372 |
| Release | : 1998-04-23 |
| Genre | : Science |
| ISBN | : 113945739X |
Download Biological Sequence Analysis Book in PDF, ePub and Kindle
Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
| Author | : Scott T. Kelley |
| Publisher | : John Wiley & Sons |
| Total Pages | : 181 |
| Release | : 2018-01-01 |
| Genre | : Science |
| ISBN | : 1683673034 |
Download Computational Biology Book in PDF, ePub and Kindle
This textbook is for anyone who needs to learn the basics of bioinformatics—the use of computational methods to better understand biological systems. Computational Biology covers the principles and applications of the computational methods used to study DNA, RNA, and proteins, including using biological databases such as NCBI and UniProt; performing BLAST, sequence alignments, and structural predictions; and creating phylogenetic trees. It includes a primer that can be used as a jumping off point for learning computer programming for bioinformatics. This text can be used as a self-study guide, as a course focused on computational methods in biology/bioinformatics, or to supplement general courses that touch on topics included within the book. Computational Biology's robust interactive online components “gamify” the study of bioinformatics, allowing the reader to practice randomly generated problems on their own time to build confidence and skill and gain practical real-world experience. The online component also assures that the content being taught is up to date and accurately reflects the ever-changing landscape of bioinformatics web-based programs.
| Author | : Hamid D. Ismail |
| Publisher | : CRC Press |
| Total Pages | : 466 |
| Release | : 2022-03-23 |
| Genre | : Science |
| ISBN | : 1000519074 |
Download Bioinformatics Book in PDF, ePub and Kindle
Bioinformatics: A Practical Guide to NCBI Databases and Sequence Alignments provides the basics of bioinformatics and in-depth coverage of NCBI databases, sequence alignment, and NCBI Sequence Local Alignment Search Tool (BLAST). As bioinformatics has become essential for life sciences, the book has been written specifically to address the need of a large audience including undergraduates, graduates, researchers, healthcare professionals, and bioinformatics professors who need to use the NCBI databases, retrieve data from them, and use BLAST to find evolutionarily related sequences, sequence annotation, construction of phylogenetic tree, and the conservative domain of a protein, to name just a few. Technical details of alignment algorithms are explained with a minimum use of mathematical formulas and with graphical illustrations. Key Features Provides readers with the most-used bioinformatics knowledge of bioinformatics databases and alignments including both theory and application via illustrations and worked examples. Discusses the use of Windows Command Prompt, Linux shell, R, and Python for both Entrez databases and BLAST. The companion website contains tutorials, R and Python codes, instructor materials including slides, exercises, and problems for students. This is the ideal textbook for bioinformatics courses taken by students of life sciences and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.
| Author | : Jeremy Ramsden |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 274 |
| Release | : 2009-04-29 |
| Genre | : Science |
| ISBN | : 1848002572 |
Download Bioinformatics Book in PDF, ePub and Kindle
The field of bioinformatics continues to develop energetically. This second edition covers new findings using the formula of the original text. It is self-contained, bringing together the multiple disciplines necessary for a profound grasp of the field.
