Free Radical Toxicology PDF Download
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| Author | : Kendall B Wallace |
| Publisher | : CRC Press |
| Total Pages | : 458 |
| Release | : 1997-06-19 |
| Genre | : Medical |
| ISBN | : 9781439805701 |
Download Free Radical Toxicology Book in PDF, ePub and Kindle
Provides insight into the involvement of free radicals in the pathogenesis of chemical-induced toxic tissue injury. The text addresses the fundamentals of free radical chemistry and the theoretical basis for electron transfer reaction leading to free radical generation. It describes the various subcellular sources of free radicals, the biological reactivity with lipid, protein and nucleic acids, and the physiochemical determinants of free radical-induced cell injury and the various antioxidant defence systems. The book focuses on target organ toxicity, and the concluding section offers an overview of the evidence implicating free radicals in the aetiology of various chemical toxicities, challenging the possibility of misguided use of biomarkers for oxidative damage.
| Author | : Chris J Rhodes |
| Publisher | : CRC Press |
| Total Pages | : 514 |
| Release | : 2000-02-24 |
| Genre | : Science |
| ISBN | : 9780748409167 |
Download Toxicology of the Human Environment Book in PDF, ePub and Kindle
The environment in which human beings live is complex and we may encounter many different potentially toxic chemical substances during the course of our lives. These xenobiotic agents may invade the living system in the form of environmental pollutants, in the diet, as pharmaceutically administered compounds or even as chemical weapons and it is becoming widely recognised that free radicals are often involved in this toxicity. The book covers all aspects of toxic agents in the environment from their detection to their effects. Final year undergraduates and postgraduates studying toxicology, biochemistry, cell biology or environmental science will find this book valuable reading, whilst researchers in academia, the pharmaceutical industry, and public health laboratories will appreciate it as a comprehensive reference.
| Author | : Kavindra Kumar Kesari |
| Publisher | : Springer Nature |
| Total Pages | : 392 |
| Release | : 2022-03-11 |
| Genre | : Medical |
| ISBN | : 3030834468 |
Download Free Radical Biology and Environmental Toxicity Book in PDF, ePub and Kindle
The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of free radical research and environmental toxicity. This book presents various state-of-the-art chapters of recent progress in the field of cellular toxicology and clinical manifestations of various disorders. Topics include cell signaling, various risk factors, the pathophysiology of disease instigation and distribution, mechanistic insights into metal and nanoparticle toxicity, neural toxicity, nongenotoxic carcinogenicity, immune and idiosyncratic toxicity, prevention, biomarkers related to disease progression and therapeutic strategies. In particular, this book provides valuable insight for researchers, pathologists, and clinicians with an interest in toxicological research and cellular impairments with special emphasis on therapeutic advancement.
| Author | : Vinood B. Patel |
| Publisher | : Academic Press |
| Total Pages | : 596 |
| Release | : 2020-11-17 |
| Genre | : Medical |
| ISBN | : 0128190930 |
Download Toxicology Book in PDF, ePub and Kindle
Toxicology: Oxidative Stress and Dietary Antioxidants examines the nature of oxidative stress as a consequence of exposure to toxins and how antioxidant approaches can mitigate the impact of toxicant exposures. Sections covers the basic biology of oxidative stress, from molecular biology, to physiological pathology, mechanisms of action of specific toxicants, metals and other chemicals/drugs, and antioxidant approaches and therapies for toxic exposures. With contributions from an international group of experts, useful summary sections, a dictionary of terms, and applications to other areas of toxicology, this book is an informative, consolidated reference that helps bridge the interrelationship between toxicology, oxidative stress and antioxidants. Provides a novel collection of information linking both sides of redox biology (oxidants and antioxidants) and toxicology Explores the role of free radical mediated damage and toxicology Contains contributions from experts on toxicological science surrounding oxidative stress and on antioxidant approaches for reducing the impact of toxicant exposures
| Author | : Roberfroid |
| Publisher | : CRC Press |
| Total Pages | : 292 |
| Release | : 1994-12-14 |
| Genre | : Medical |
| ISBN | : 9780824795870 |
Download Free Radicals and Oxidation Phenomena in Biological Systems Book in PDF, ePub and Kindle
This work offers an analysis of the biological processes mediated by free radicals, from a toxicological point of view, providing easy access to information in an integrated, coherent presentation. The chemistry and biochemistry of all principal types of radical are explained, and the multiple forms in whch radicals participate in living organisms are investigated.;This work should be of use to biochemists, pharmacologists, pharmaceutical researchers, food scientists and technologists, nutritionists, toxicologists, chemists, biologists and graduate students in these disciplines.
| Author | : Barry Halliwell |
| Publisher | : OUP Oxford |
| Total Pages | : 961 |
| Release | : 2015-08-21 |
| Genre | : Science |
| ISBN | : 0191026980 |
Download Free Radicals in Biology and Medicine Book in PDF, ePub and Kindle
Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.
| Author | : Stephen M. Roberts |
| Publisher | : Humana Press |
| Total Pages | : 496 |
| Release | : 2015-09-30 |
| Genre | : Science |
| ISBN | : 3319190962 |
Download Studies on Experimental Toxicology and Pharmacology Book in PDF, ePub and Kindle
This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections with chapters on toxicological mechanisms, agents that produce toxicity, and special topics including areas such as antioxidant supplements, oxygen toxicity, toxicogenomics, and marine biology. Studies on Experimental Toxicology and Pharmacology promotes the concept of using biomarkers of free radical- and reactive species-induced injury as adjuncts to classical laboratory testing and the ability of antioxidants to provide cellular protection. There is increasing evidence that free radicals and other reactive species are causative, or at least supporting factors, that impact organisms and cause numerous tissue disorders. With contributions from international experts in the field, this volume is a valuable resource for researchers and postgraduate students in toxicology and related fields, as well as clinicians and clinical researchers.
| Author | : Munday |
| Publisher | : Academic Press |
| Total Pages | : |
| Release | : 2018-10 |
| Genre | : |
| ISBN | : 9780128122686 |
Download Free Radical Toxicology: the Harmful and Beneficial Effects of Reactive Oxygen Species Book in PDF, ePub and Kindle
| Author | : C.A. Rice-Evans |
| Publisher | : Elsevier |
| Total Pages | : 409 |
| Release | : 1994-02-09 |
| Genre | : Science |
| ISBN | : 0080860885 |
Download Free Radical Damage and its Control Book in PDF, ePub and Kindle
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
| Author | : Steven Baskin |
| Publisher | : Routledge |
| Total Pages | : 392 |
| Release | : 2017-11-01 |
| Genre | : Medical |
| ISBN | : 1351426222 |
Download Oxidants, Antioxidants And Free Radicals Book in PDF, ePub and Kindle
This volume collates articles investigating antioxidant, oxidant and free radical research. It examines the role of such research in health and disease, particulary with respect to developing greater understanding about the many interactions between oxidants and antioxidants, and how such substances may act as natural protectants and /or natural toxicants.
