Drug Discovery In Africa PDF Download
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Author | : Kelly Chibale |
Publisher | : Springer Science & Business Media |
Total Pages | : 453 |
Release | : 2012-08-09 |
Genre | : Science |
ISBN | : 3642281753 |
Download Drug Discovery in Africa Book in PDF, ePub and Kindle
Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, this book presents the science and strategies of modern drug discovery. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challenges, which are presented when attempting to engage in full-scale drug discovery. Topics addressed are varied; from African medicinal plants to marine bioprospecting, pharmacogenetics and the use of nanotechnology. This book brings together for the first time a collection of strategies and techniques that need to be considered when developing drugs in an African setting. It is an unprecedented and truly international effort, highlighting the remarkable effort made so far in the area of drug discovery research by African scientists, and scientists from other parts of the world working on African health problems.
Author | : Anne Pollock |
Publisher | : University of Chicago Press |
Total Pages | : 198 |
Release | : 2019-05-08 |
Genre | : Medical |
ISBN | : 022662918X |
Download Synthesizing Hope Book in PDF, ePub and Kindle
Synthesizing Hope opens up the material and social world of pharmaceuticals by focusing on an unexpected place: iThemba Pharmaceuticals. Founded in 2009 with a name taken from the Zulu word for hope, the small South African startup with an elite international scientific board was tasked with drug discovery for tuberculosis, HIV, and malaria. Anne Pollock uses this company as an entry point for exploring how the location of scientific knowledge production matters, not only for the raw materials, manufacture, licensing, and distribution of pharmaceuticals but also for the making of basic scientific knowledge. Consideration of this case exposes the limitations of global health frameworks that implicitly posit rich countries as the only sites of knowledge production. Analysis of iThemba identifies the problems inherent in global north/south divides at the same time as it highlights what is at stake in who makes knowledge and where. It also provides a concrete example for consideration of the contexts and practices of postcolonial science, its constraints, and its promise. Synthesizing Hope explores the many legacies that create conditions of possibility for South African drug discovery, especially the specific form of settler colonialism characterized by apartheid and resource extraction. Paying attention to the infrastructures and laboratory processes of drug discovery underscores the materiality of pharmaceuticals from the perspective of their makers, and tracing the intellectual and material infrastructures of South African drug discovery contributes new insights about larger social, political, and economic orders.
Author | : Anne Pollock |
Publisher | : University of Chicago Press |
Total Pages | : 198 |
Release | : 2019-05-08 |
Genre | : Medical |
ISBN | : 022662921X |
Download Synthesizing Hope Book in PDF, ePub and Kindle
Synthesizing Hope opens up the material and social world of pharmaceuticals by focusing on an unexpected place: iThemba Pharmaceuticals. Founded in 2009 with a name taken from the Zulu word for hope, the small South African startup with an elite international scientific board was tasked with drug discovery for tuberculosis, HIV, and malaria. Anne Pollock uses this company as an entry point for exploring how the location of scientific knowledge production matters, not only for the raw materials, manufacture, licensing, and distribution of pharmaceuticals but also for the making of basic scientific knowledge. Consideration of this case exposes the limitations of global health frameworks that implicitly posit rich countries as the only sites of knowledge production. Analysis of iThemba identifies the problems inherent in global north/south divides at the same time as it highlights what is at stake in who makes knowledge and where. It also provides a concrete example for consideration of the contexts and practices of postcolonial science, its constraints, and its promise. Synthesizing Hope explores the many legacies that create conditions of possibility for South African drug discovery, especially the specific form of settler colonialism characterized by apartheid and resource extraction. Paying attention to the infrastructures and laboratory processes of drug discovery underscores the materiality of pharmaceuticals from the perspective of their makers, and tracing the intellectual and material infrastructures of South African drug discovery contributes new insights about larger social, political, and economic orders.
Author | : M.M. Iwu |
Publisher | : Elsevier |
Total Pages | : 347 |
Release | : 2002-03-01 |
Genre | : Science |
ISBN | : 0080531253 |
Download Ethnomedicine and Drug Discovery Book in PDF, ePub and Kindle
Approx.344 pages
Author | : Andrew G. Mtewa |
Publisher | : John Wiley & Sons |
Total Pages | : 444 |
Release | : 2020-12-22 |
Genre | : Science |
ISBN | : 1119650232 |
Download Poisonous Plants and Phytochemicals in Drug Discovery Book in PDF, ePub and Kindle
Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Author | : Academy of Science of South Africa |
Publisher | : National Academies Press |
Total Pages | : 146 |
Release | : 2011-03-22 |
Genre | : Medical |
ISBN | : 0309211603 |
Download The Emerging Threat of Drug-Resistant Tuberculosis in Southern Africa Book in PDF, ePub and Kindle
Tuberculosis (TB) kills approximately 4,500 people worldwide every day. While most cases of TB can be treated with antibiotics, some strains have developed drug resistance that makes their treatment more expensive, more toxic and less effective for the patient. The IOM Forum on Drug Discovery, Development, and Translation and the Academy of Science of South Africa held a workshop to discuss ways to fight the growing threat of drug-resistant TB.
Author | : Maano Ramutsindela |
Publisher | : Springer |
Total Pages | : 295 |
Release | : 2019-06-13 |
Genre | : Science |
ISBN | : 3030148572 |
Download Africa and the Sustainable Development Goals Book in PDF, ePub and Kindle
The book draws upon the expertise and international research collaborations forged by the Worldwide Universities Network Global Africa Group to critically engage with the intersection, in theory and practice, of the Sustainable Development Goals (SDGs) and Africa’s development agendas and needs. Further, it argues that – and demonstrates how – the SDGs should be understood as an aspirational blueprint for development with multiple meanings that are situated in dynamic and contested terrains. As the SDGs have substantial implications for development policy and resourcing at both the macro and micro levels, their relevance is not only context-specific but should also be assessed in terms of the aspirations and needs of ordinary citizens across the continent. Drawing on analyses and evidence from both the natural and social sciences, the book demonstrates that progress towards the SDGs must meet demands for improving human well-being under diverse and challenging socio-economic, political and environmental conditions. Examples include those from the mining industry, public health, employment and the media. In closing, it highlights how international collaboration in the form of research networks can enhance the production of critical knowledge on and engagement with the SDGs in Africa.
Author | : Abena Dove Osseo-Asare |
Publisher | : University of Chicago Press |
Total Pages | : 309 |
Release | : 2014-01-13 |
Genre | : Science |
ISBN | : 022608616X |
Download Bitter Roots Book in PDF, ePub and Kindle
For over a century, plant specialists worldwide have sought to transform healing plants in African countries into pharmaceuticals. And for equally as long, conflicts over these medicinal plants have endured, from stolen recipes and toxic tonics to unfulfilled promises of laboratory equipment and usurped personal patents. In Bitter Roots, Abena Dove Osseo-Asare draws on publicly available records and extensive interviews with scientists and healers in Ghana, Madagascar, and South Africa to interpret how African scientists and healers, rural communities, and drug companies—including Pfizer, Bristol-Myers Squibb, and Unilever—have sought since the 1880s to develop drugs from Africa’s medicinal plants. Osseo-Asare recalls the efforts to transform six plants into pharmaceuticals: rosy periwinkle, Asiatic pennywort, grains of paradise, Strophanthus, Cryptolepis, and Hoodia. Through the stories of each plant, she shows that herbal medicine and pharmaceutical chemistry have simultaneous and overlapping histories that cross geographic boundaries. At the same time, Osseo-Asare sheds new light on how various interests have tried to manage the rights to these healing plants and probes the challenges associated with assigning ownership to plants and their biochemical components. A fascinating examination of the history of medicine in colonial and postcolonial Africa, Bitter Roots will be indispensable for scholars of Africa; historians interested in medicine, biochemistry, and society; and policy makers concerned with drug access and patent rights.
Author | : Antony D. Buss |
Publisher | : Royal Society of Chemistry |
Total Pages | : 459 |
Release | : 2010 |
Genre | : Medical |
ISBN | : 0854041931 |
Download Natural Product Chemistry for Drug Discovery Book in PDF, ePub and Kindle
This text provides a comprehensive summary of where natural product chemistry is today in drug discovery. It covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 312 |
Release | : 1991-02-01 |
Genre | : Medical |
ISBN | : 9780309045278 |
Download Malaria Book in PDF, ePub and Kindle
Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.