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Author | : |
Publisher | : Elsevier |
Total Pages | : 273 |
Release | : 2012-10-16 |
Genre | : Medical |
ISBN | : 0444543007 |
Download Down Syndrome: From Understanding the Neurobiology to Therapy Book in PDF, ePub and Kindle
Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Author | : Kathryn Anne McCullough |
Publisher | : |
Total Pages | : |
Release | : 2016-09-03 |
Genre | : |
ISBN | : 9781939275431 |
Download Ups and Downs Book in PDF, ePub and Kindle
Kathy McCullough learned to fly at the age of sixteen, but her story began much earlier. Her challengers, accomplishments, and indomitable spirit come to life within the pages of Ups and Downs. Becoming the fourth woman pilot hired by Northwest Orient Airlines in 1981 and earning her captain wings in the Boeing 747 a quarter of a century later, was not an easy journey. There is no better way to understand the gender issues in a cockpit than through the eyes of a woman pilot who lived the many challenges. Kathy takes us on the flight of he life with compelling stories of what it took to get into the cockpit of the largest airplane of its time, and what it took to stay there. Now retired, Kathy lives with her husband Kevin on a wheat ranch in eastern Oregon. She shares her experiences with young adults, inspiring them to explore the world. Everyone who has a goal in life will see herself in the pages of this book. Anyone who has had a dream come true will empathize with the struggle it takes to make that dream a reality. And each of us who has a thirst for adventure can take a long drink from these pages. What does it take to become a female pilot? Exactly the same thing it takes for you to achieve your dreams.
Author | : David Wright |
Publisher | : Oxford University Press |
Total Pages | : 254 |
Release | : 2011-08-25 |
Genre | : Language Arts & Disciplines |
ISBN | : 019956793X |
Download Downs Book in PDF, ePub and Kindle
Editorial Advisor, Helen Bynum is a freelancer historian and author. --Book Jacket.
Author | : Donald Alexander Downs |
Publisher | : University of Chicago Press |
Total Pages | : 332 |
Release | : 1998-10 |
Genre | : Family & Relationships |
ISBN | : 9780226161600 |
Download More Than Victims Book in PDF, ePub and Kindle
Donald Downs offers an analysis of the injustices behind the logic of battered woman syndrome, concluding that this very logic harms those it is trying to protect. This work seeks to rethink the criminal justice system.
Author | : Elizabeth Diane Downs |
Publisher | : Danmark Pub |
Total Pages | : 336 |
Release | : 1989-03-01 |
Genre | : Female offenders |
ISBN | : 9780962274503 |
Download Diane Down's Book in PDF, ePub and Kindle
Author | : Hull City Council |
Publisher | : Routledge |
Total Pages | : 50 |
Release | : 2013-01-11 |
Genre | : Education |
ISBN | : 1136757198 |
Download Supporting Children with Down's Syndrome Book in PDF, ePub and Kindle
Off-the-shelf support containing all the vital information practitioners need to know about Down's Syndrome, this book includes * Definition of Down's Syndrome and its educational implications * Teaching strategies to meet different learning styles * Advice on managing staff
Author | : Susan van Duyne |
Publisher | : Springer Science & Business Media |
Total Pages | : 241 |
Release | : 2012-12-06 |
Genre | : Psychology |
ISBN | : 1461396441 |
Download Clinical Perspectives in the Management of Down Syndrome Book in PDF, ePub and Kindle
The management of and attitudes toward children and adults with Down syndrome have undergone considerable changes in the course of the condi tion's long history (Zellweger, 1977, 1981, Zellweger & Patil, 1987). J. E. D. Esquirol (1838) and E. Seguin (1846) were probably the first physicians to witness the condition without using currently accepted diagnostic designa tions. Seguin coined the terms furfuraceus or lowland cretinism in contradis tinction to the goiterous cretinism endemic at that time in the Swiss Alps. Esquirol, as well as Seguin, had a positive attitude toward persons who were mentally ill or mentally subnormal. Esquirol pioneered a more humane treatment in mental institutions and Seguin created the first homes in France, and later in the United States, aimed at educating persons who were mentally subnormal. The term mongolian idiocy was coined by J. H. L. Down in England (1866). The term is misleading in several respects: (1) Down identified the epicanthic folds seen in many children with Down syndrome with the additional skin fold in the upper lid occurring particularly in people of Oriental (Mongolian) descent; and (2) Down also erred by assuming that Down syndrome represented regression to an ethnic variant of lower cultural standing. Such an interpretation might have been understandable at a time when the myth of Anglo-Saxon superiority was widely accepted by the British. Charles Darwin's then highly acclaimed theory of origin of the species may have contributed to such a concept.
Author | : Samuel Benner |
Publisher | : BoD – Books on Demand |
Total Pages | : 138 |
Release | : 2024-05-31 |
Genre | : Fiction |
ISBN | : 338548815X |
Download Benner's Prophecies of Future Ups and Downs in Prices. What Years to Make Money on Pig-iron, Hogs, Corn, and Provisions Book in PDF, ePub and Kindle
Reprint of the original, first published in 1876.
Author | : |
Publisher | : |
Total Pages | : 96 |
Release | : 1928 |
Genre | : |
ISBN | : |
Download Collins v. Searight-Downs Manfg. Co., 245 MICH 41 (1928) Book in PDF, ePub and Kindle
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Author | : Alfred Martin Lucas |
Publisher | : |
Total Pages | : 360 |
Release | : 1972 |
Genre | : Agriculture |
ISBN | : |
Download Avian Anatomy Integument Book in PDF, ePub and Kindle