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| Author | : Pierre Baldi |
| Publisher | : Cambridge University Press |
| Total Pages | : 238 |
| Release | : 2011-04-28 |
| Genre | : Science |
| ISBN | : 9781139437608 |
Download DNA Microarrays and Gene Expression Book in PDF, ePub and Kindle
Massive data acquisition technologies, such as genome sequencing, high-throughput drug screening, and DNA arrays are in the process of revolutionizing biology and medicine. Using the mRNA of a given cell, at a given time, under a given set of conditions, DNA microarrays can provide a snapshot of the level of expression of all the genes in the cell. Such snapshots can be used to study fundamental biological phenomena such as development or evolution, to determine the function of new genes, to infer the role individual genes or groups of genes may play in diseases, and to monitor the effect of drugs and other compounds on gene expression. Originally published in 2002, this inter-disciplinary introduction to DNA arrays will be of value to anyone with an a interest in this powerful technology.
| Author | : B.R. Jordan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 139 |
| Release | : 2013-12-01 |
| Genre | : Medical |
| ISBN | : 3642565174 |
Download DNA Microarrays: Gene Expression Applications Book in PDF, ePub and Kindle
This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book.
| Author | : Mark Schena |
| Publisher | : Scion Publishing Ltd |
| Total Pages | : 289 |
| Release | : 2007-10-01 |
| Genre | : Science |
| ISBN | : 1907904395 |
Download DNA Microarrays Book in PDF, ePub and Kindle
DNA Microarrays: Methods Express covers the very latest in DNA microarray technology, with a clear focus on how these techniques can be used in the lab to gain the very best results. The authors are from some of the leading laboratories in the field and write with real authority on the latest methodology. Every chapter provides detailed step-by-step protocols with valuable hints and tips for success, as well as giving typical experimental results and selected literature citations. This book is a 'must have' manual for researchers in all fields of biology, medicine and agriculture.
| Author | : Helen Causton |
| Publisher | : John Wiley & Sons |
| Total Pages | : 176 |
| Release | : 2009-04-01 |
| Genre | : Science |
| ISBN | : 1444311565 |
Download Microarray Gene Expression Data Analysis Book in PDF, ePub and Kindle
This guide covers aspects of designing microarray experiments and analysing the data generated, including information on some of the tools that are available from non-commercial sources. Concepts and principles underpinning gene expression analysis are emphasised and wherever possible, the mathematics has been simplified. The guide is intended for use by graduates and researchers in bioinformatics and the life sciences and is also suitable for statisticians who are interested in the approaches currently used to study gene expression. Microarrays are an automated way of carrying out thousands of experiments at once, and allows scientists to obtain huge amounts of information very quickly Short, concise text on this difficult topic area Clear illustrations throughout Written by well-known teachers in the subject Provides insight into how to analyse the data produced from microarrays
| Author | : Pierre Baldi |
| Publisher | : |
| Total Pages | : 213 |
| Release | : 2002-09-19 |
| Genre | : Science |
| ISBN | : 9780521800228 |
Download DNA Microarrays and Gene Expression Book in PDF, ePub and Kindle
Concise, 2002 inter-disciplinary introduction to DNA microarray technology, which is revolutionizing biology and medicine.
| Author | : Richard M. Simon |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 205 |
| Release | : 2006-05-09 |
| Genre | : Medical |
| ISBN | : 0387218661 |
Download Design and Analysis of DNA Microarray Investigations Book in PDF, ePub and Kindle
The analysis of gene expression profile data from DNA micorarray studies are discussed in this book. It provides a review of available methods and presents it in a manner that is intelligible to biologists. It offers an understanding of the design and analysis of experiments utilizing microarrays to benefit scientists. It includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is available from the National Cancer Institute.
| Author | : Aidong Zhang |
| Publisher | : World Scientific Publishing Company |
| Total Pages | : 356 |
| Release | : 2006-06-27 |
| Genre | : Science |
| ISBN | : 9813106646 |
Download Advanced Analysis Of Gene Expression Microarray Data Book in PDF, ePub and Kindle
This book focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data.Biomedical researchers will find this book invaluable for learning the cutting-edge methods for analyzing gene expression microarray data. Specifically, the coverage includes the following state-of-the-art methods:• Gene-based analysis: the latest novel clustering algorithms to identify co-expressed genes and coherent patterns in gene expression microarray data sets• Sample-based analysis: supervised and unsupervised methods for the reduction of the gene dimensionality to select significant genes. A series of approaches to disease classification and discovery are also described• Pattern-based analysis: methods for ascertaining the relationship between (subsets of) genes and (subsets of) samples. Various novel pattern-based clustering algorithms to find the coherent patterns embedded in the sub-attribute spaces are discussed• Visualization tools: various methods for gene expression data visualization. The visualization process is intended to transform the gene expression data set from high-dimensional space into a more easily understood two- or three-dimensional space.
| Author | : Ulrike Nuber |
| Publisher | : Garland Science |
| Total Pages | : 299 |
| Release | : 2007-02-08 |
| Genre | : Science |
| ISBN | : 020396733X |
Download DNA Microarrays Book in PDF, ePub and Kindle
DNA Microarrays introduces all up-to-date microarray platforms and their various applications. It is written for scientists who are entering the field of DNA microarrays as well as those already familiar with the technology, but interested in new applications and methods.
| Author | : Mark Schena |
| Publisher | : Practical Approach Series |
| Total Pages | : 236 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : 9780199637768 |
Download DNA Microarrays Book in PDF, ePub and Kindle
DNA Microarrays: A Practical Approach is the first comprehensive overview of an exciting and powerful new technology. DNA microarrays, or biochips, are small glass chips embedded with ordered rows of DNA, providing a massive parallel platform for data gathering and representing a fundamental technical advance in biomedical research. Such biochips gather data at an unprecedented rate by enabling the use of advanced fabrication, detection, and data mining technologies. Written and edited by experts in the field, this book provides fascinating insight into this remarkable advancement. It opens with an introduction to the technology of DNA microarrays, emphasizing the methodological fundamentals of biochips, and continues with descriptions of the use of confocal scanning in microarray detection and techniques for the efficient cloning and screening of differentially expressed genes. The chapters address many topics, among them assay optimization, antisense scanning arrays, the manufacture of molecular arrays, and gene expression analysis. Also addressed are the uses of expression data in bioinformatics, of active microelectronic arrays for DNA hybridization analysis, and of microarray technology in pharmacogenomics. DNA Microarrays: A Practical Approach is ideal for researchers investigating patterns of gene expression (and the relationship with disease), and it is essential for any researcher interested in the use of biochips.
| Author | : Gary Hardiman |
| Publisher | : CRC Press |
| Total Pages | : 362 |
| Release | : 2009-04-02 |
| Genre | : Medical |
| ISBN | : 1420094513 |
Download Microarray Innovations Book in PDF, ePub and Kindle
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr
