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Recent Advances in Biological Psychiatry

Recent Advances in Biological Psychiatry
Author: Joseph Wortis
Publisher: Springer Science & Business Media
Total Pages: 375
Release: 2012-12-06
Genre: Medical
ISBN: 1468482289

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Qualitative evaluations of buccal smear specimens have indicated an unusually high incidence of triple-X females in a hospitalized schizo phrenic population. Specimens from adult prisoners have also indicated an unusually high incidence of triple-X females. Studies of a population of confined juvenile offenders, on the other hand, have indicated an unusually high incidence of one-X females. No unusual indications were observed in a population of "normal" volunteer females. The data and their implications are discussed in context with previous observations. ACKNOWLEDGMENTS This study was made possible primarily by research grants from the Scottish Rite Committee on Research in Schizophrenia, The National Association for Mental Health, Inc. Additional support was provided by a grant from the National Institutes of Health, GRS-05563. The study has been supported by the State of Ohio, Department of Mental Hygiene and Correction, Division of Mental Hygiene. The author is particularly indebted to Edward N. Hinko, M.D., Regional Director of Research, whose advice and help made the present study possible. Invaluable cooperation and help have been received from the following administrators and their staffs: F. A. Lingl, M.D. (Cleve land Psychiatric Institute); Martha Wheeler (Ohio Reformatory for Women); M. B. McLane (Scioto Village); M. B. Holmes, M. D., and S. Caruso, M. D. (Massillon State Hospital); G. F. Ogram, M. D. (Athens State Hospital); C. Waltner, M. D. (Woodside Receiving Hospital); A. Mako, M. D. (Fairhill Psychiatric Hospital); and W. G. Stover, M. D.


Recent Advances in Biological Psychiatry

Recent Advances in Biological Psychiatry
Author: Joseph Wortis
Publisher: Springer Science & Business Media
Total Pages: 340
Release: 2013-04-17
Genre: Medical
ISBN: 1468490729

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A method of behavioral control which utilizes nutritive sucking as the operant has been evolved in our laboratory. Using this technique we studied the role of arousal and learning in the development of environ mental control over earliest feeding behavior. Few of the infants in our studies were able to coordinate their sucking behavior to arbitrary operant-discrimination schedules, but when the individual pattern of suck ing was taken into consideration, some infants rapidly adapted to the reinforcement schedule. Data from various reinforcement schedules suggest that earliest mothering involves a mutual adaptation in which the nurturing environment approximates and then entrains the infant's feeding behavior by a perceptive manipulation of the infant's state of arousal. Coordination between the infant and its environment sets the stage for associative learning, which develops following maturation of the infant's discriminative and response capacities. The process of behavioral acquisition begins with unconditioned feeding responses, which are transformed into complex learned behavior through the mediation of an appropriately reinforcing environment. The infants studied showed individual differences in susceptibility to environmental control and in response to frustration. The relative importance of arousal and learning as determinants of infant behavior are discussed and a hypothetical model for the earliest mother-infant relationship is proposed.


Personalized Psychiatry

Personalized Psychiatry
Author: Bernhard Baune
Publisher: Academic Press
Total Pages: 604
Release: 2019-10-16
Genre: Medical
ISBN: 0128131772

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Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective


Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness
Author: Anne Harrington
Publisher: W. W. Norton & Company
Total Pages: 384
Release: 2019-04-16
Genre: Psychology
ISBN: 1324001976

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Mind Fixers tells the history of psychiatry’s quest to understand the biological basis of mental illness and asks where we need to go from here. In Mind Fixers, Anne Harrington, author of The Cure Within, explores psychiatry’s repeatedly frustrated struggle to understand mental disorder in biomedical terms. She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds. But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time. Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well. In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones. A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.


The Disordered Mind

The Disordered Mind
Author: George Graham
Publisher: Routledge
Total Pages: 303
Release: 2014-08-07
Genre: Philosophy
ISBN: 1135160147

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"George Graham is contemporary philosophy’s most gifted and humane writer. The Disordered Mind is a wise, deep, and thorough inquiry into the nature of the human mind and the various ‘creaks, cracks, and crevices’ into which it is prone sometimes to wander." Owen Flanagan, Duke University, USA "The book is a success, it is consistently insightful and humane, and conveys a clear understanding not only of relevant philosophical topics, but also of a much more difficult issue, the relevance of those topics to understanding mental illness." Philip Gerrans, University of Adelaide, Australia "The Disordered Mind is a must read for anyone who is a psychiatrist, psychologist, philosopher, neurologist, or mental health worker. Indeed, it is a must read for any thoughtful person who simply desires to understand more deeply and more realistically the workings of their own mind as well as the workings of the human mind in general." Richard Garrett, Bentley University, USA Mental disorder raises profound questions about the nature of the mind. The Disordered Mind: An Introduction to Philosophy of Mind and Mental Illness is the first book to systematically examine and explain, from a philosophical standpoint, what mental disorder is: its reality, causes, consequences, and more. It is also an outstanding introduction to philosophy of mind from the perspective of mental disorder. Each chapter explores a central question or problem about mental disorder, including: What is mental disorder and can it be distinguished from neurological disorder? What roles should reference to psychological, cultural, and social factors play in the medical/scientific understanding of mental disorder? What makes mental disorders undesirable? Are they diseases? Mental disorder and the mind–body problem Is mental disorder a breakdown of rationality? What is a rational mind? Addiction, responsibility and compulsion Ethical dilemmas posed by mental disorder, including questions of dignity and self-respect. Each topic is clearly explained and placed in both a clinical and philosophical context. Mental disorders discussed include clinical depression, dissociative identity disorder, anxiety, religious delusions, and paranoia. Several non-mental neurological disorders that possess psychological symptoms are also examined, including Alzheimer’s disease, Down’s syndrome, and Tourette’s syndrome. Additional features, such as chapter summaries and annotated further reading, provide helpful tools for those coming to the subject for the first time. Throughout, George Graham draws expertly on issues that cut across philosophy, science, and psychiatry. As such, The Disordered Mind is a superb introduction to the philosophy of mental disorder for students of philosophy, psychology, psychiatry, and related mental health professions. PHILOSOPHY/PSYCHOLOGY